10 Nā Pono Ola Kamahaʻo o Akuamma

ʻO ke Akuamma, i kapa ʻia ʻo Picralima Nitida, hele mai ia mai kahi kumu lāʻau like me nā kumulāʻau (e like ke kiʻekiʻe me nā mea kanu Kratom) e ulu ana ma nā kapa muliwai ma West Africa. ʻO nā alkaloids nui i loaʻa i loko o nā hua Akuamma ʻo Akuammine a me Pericine - ua like lāua me Mitragynine ma Kratom.

No ka mea, ua like loa ke Akuamma ma nā ʻano he nui - ua like loa ka hopena o ka lawe ʻana i ka hua Akuamma me ka ʻai ʻana i nā lau Kratom.

ʻO nā alkaloids koʻikoʻi e hana ana i ka mea kanu i mea ikaika a maikaʻi hoʻi;

• Akuammidine- ʻo ia ka alkaloid nui o nā hua a hana ma ka hoʻoulu ʻana i nā wahi paʻa opioid. Hāʻawi ka alkaloid i nā ʻano analgesic e kōkua i ka hoʻopau ʻana i ka ʻeha a me ka lawelawe ʻana ma ke ʻano he hoʻomaha ʻiʻo.
• ʻO ke Akuammine- ʻoi aku ka pili o kēia alkaloid no nā wahi hoʻopaʻa mu-opioid, ʻaʻole like me ke Akuammidine. Hiki ke kōkua i ka hāʻawi ʻana i nā hopena analgesic, akā naʻe, hiki ke hana i kahi hopena pale i ka neʻe peristaltic o nā ʻōpū inā hoʻohana ʻia i nā koina kiʻekiʻe.
• ʻO ke Akuammicine- ʻo kēia alkaloid, ma kekahi ʻaoʻao, ʻoi aku ka kiʻekiʻe o ka pilina no nā wahi paʻa kappa-opioid.
• Pseudo-Akuammigine- hāʻawi kēia alkaloid i nā hopena anti-inflammatory a me analgesic. Ma muli o ke ʻano, hoʻohauʻoli ka alkaloid, hoʻololi i ka hoʻopaʻa ʻana o ka ʻiʻo iwi, ka hoʻopaʻa ʻana i ka ʻiʻo maʻemaʻe, ka ʻōnaehana nūnū waena, a me ka hanu.
• Akuammigine- ua hōʻike wale kēia i ka hopena anti-adrenergic ma nā kīʻaha koko a me ka puʻuwai.
• ʻO Pericine - ua hōʻike ʻia kēia e hoʻopaʻa i nā mea loaʻa mu-opioid, akā naʻe, hiki ke hoʻoulu i ka convulsion e hopena i ka ʻoki ʻana o nā ʻiʻo.

Manaʻo ʻia ʻo Akuamma i kēia lā he ʻoi aku ka maikaʻi ma mua o nā mea koʻikoʻi ʻē aʻe no ka mea e hōʻoiaʻiʻo ʻia ka hoʻopau ʻana i ka ʻeha. Ua hoʻoikaika hou kēia i ka noiʻi lapaʻau nui e pili ana i ka mea kanu e hoʻomaopopo maikaʻi i ka pono o kāna waiwai olakino. Aia ma waena o nā pono olakino he nui o ke akuamma;

1) Hana Kūʻē i ka Malaria

ʻO ka alkaloid ikaika, ʻo Akuammine ke kuleana no ka hana anti-malarial. ʻO kēia ka mea e lilo ai ke akuamma kekahi o nā lāʻau anti-malarial ikaika loa i hoʻohana ʻia a puni ka honua. Ua hōʻike ʻia nā ʻāpana mai nā ʻanoʻano akuamma, ka ʻili a me ka ʻili o nā huaʻai he hana hoʻopale kūʻē i ka Plasmodium falciparum kūʻē i ka lāʻau lapaʻau no laila ke kākoʻo nei i ka ʻoiaʻiʻo ʻo ka lāʻau he lāʻau anti-malaria.

2) ʻO ka hana trypanocidal

Ua ʻike ʻia ka hopena anti-parasitic o nā hua Akuamma ma luna o nā maʻi maʻi like ʻole ʻo Trypanosoma, he protozoan parasitic e hoʻoulu ai i nā maʻi like ʻole e like me ka maʻi hiamoe ma waena o kekahi. Ua hōʻike ʻia nā haʻawina ʻepekema i ka hopena trypanocidal o nā hua akuamma.

3) Hana Kūʻē Leishmanial

ʻO Picralima Nitida kekahi o nā mea kanu nona nā unuhi i loiloi ʻia no ka hana anti-leishmanial me ka hoʻohana ʻana i kahi microtechnique radiorespirometric i hoʻokumu ʻia a me nā hopena i hoʻopaʻa ʻia e kūʻē iā Leishmania donovani ma 50 a i ʻole ka liʻiliʻi micrograms/ml.

4) Hana Antipyretic

E like me ka preliminary pharmacological study ma ka methanolic extract o akuamma, ua hōʻike nā hualoaʻa i ka potent a me ka dose-pili antipyretic hana me ka kiekie mean pākēneka Antipyrexia (38.7%) hoʻohālikelike i ka aspirin (29.0%). ʻO kēia waiwai lāʻau lapaʻau o kēia lau nahele e hōʻoiaʻiʻo i ke kumu e maʻa mau ai ia ma nā ʻāina he nui ma W. Africa.

5) Hana Analgesic

Ua hōʻike ʻia nā alkaloids i unuhi ʻia mai ke akuamma mai he hana analgesic opioid. I ka wā lōʻihi, ua huli ka poʻe e hoʻohana i ka hua akuamma no ka hoʻopau ʻana i ka ʻeha i hoʻokumu ʻia e nā maʻi e like me ka migraines, fibromyalgia, a me ka maʻi ʻāʻī i waena o nā mea ʻē aʻe.

Ua manaʻo ʻia he ʻoi aku ka maikaʻi o nā opiates e hele mai me nā hopena ʻaoʻao withdrawal a me ka addiction. ʻO nā hua mai kēia mea kanu he kūlohelohe maoli a he liʻiliʻi loa nā hopena ʻaoʻao. Hiki iā ʻoe ke lawe i nā hua no nā ʻiʻo ʻeha e loaʻa koke i ka ʻeha ma hope o 15-30 mau minuke.

6) Hana Kū'ē-Inflammatory

Ua noiʻi ʻia nā ʻāpana alkaloid mai ke akuamma no ka hana anti-inflammatory a ua hōʻike ʻia nā hopena i hōʻemi nui ʻia ka pseudo-Akuammigine i ka mean maximal a me ka pehu piha ma hope o ka lawelawe waha o ka alkaloid.

7) ʻAi ʻAi-Diarrhoeal Activity

Ua hoʻohana nui ʻia ka mea kanu Akuamma ma nā ʻāina W. ʻApelika no ka hoʻōla ʻana i nā maʻi olakino he nui e like me ka dysentery ma waena o nā maʻi ʻōpū ʻē aʻe.

Wahi a kahi noiʻi e hoʻoholo ai i ka hana anti-shigellosis o ka methanol extract o ke akuamma ma Shigella dysenteriae type 1 i hoʻoulu ʻia i ka maʻi ʻiole, ua ʻike ʻia he hopena antimicrobial ka extract i ʻumikūmākahi o nā 17 pathogenic strains i hoʻāʻo ʻia.

Ua hoʻemi nui ka extract i ka pinepine o nā feces i hoʻokuʻu ʻia. Mai kēia mau ʻike, ʻike ʻia he mea maikaʻi loa nā ʻāpana Picralima Nitida i ka hoʻopau ʻana i nā maʻi ʻōpū e like me ka maʻi maʻi.

8) Nā Hana Antioxidant a me Anti-Diabetic

ʻO ka maʻi diabetes Mellitus kahi maʻi metabolic maʻamau e pili pū ana me ke kaumaha oxidative a hōʻike ʻia e ka hyperglycemia mau.

Wahi a nā noiʻi lapaʻau e noiʻi ana i ka antioxidant a me ka ant-diabetic hiki o ka methanol extracts o nā lau a me nā ʻōpala o ka mea kanu akuamma, ua ʻike ʻia ʻo ka methanol lau extract o ka lau nahele i hōʻike i ka hana hypoglycemia kupaianaha me ka 38% o ka hōʻemi glycemia mahalo i ka alkaloid. -akuammicine, ka mea i manaʻo ʻia e hoʻoikaika i ka lawe ʻana o ka glucose i nā cell, no laila e hoʻemi ai i ke kiʻekiʻe o ka glucose i ke kahe koko.

Mai kēia mau ʻike, ua ʻike ʻia he mau antioxidant a me nā waiwai anti-diabetic ka mea kanu akuamma no laila hiki ke hoʻohana ʻia no ka mālama pono ʻana i ka maʻi maʻi mellitus a me ke kumu e hiki ai ke hoʻomohala ʻia nā lāʻau hou a ikaika e kōkua i ka mālama ʻana i ka maʻi diabetes. a me nā kūlana olakino pili.

9) Hana Hoʻomaha

Ua ʻike ʻia nā ʻano hua o kēia lau nahele e hōʻemi i ke kaumaha a me ka hopohopo e hāʻawi i kekahi i kahi hopena hoʻomaha, hoʻomaha, a hoʻomaha maʻamau. Ua hōʻike ʻia hoʻi e kōkua i ke kūʻē ʻana i ka hoʻouka kaua ʻoiai ua noʻonoʻo ʻia ʻo ia no nā kumu sedation e ka poʻe i loaʻa i nā pilikia hiamoe e like me ka insomnia a me nā moeʻuhane.

Loaʻa i nā ʻanoʻano nā mea hoʻomaha maikaʻi no laila e hōʻoiaʻiʻo i ka hiamoe maluhia loa inā lawe ʻia ma mua o ka moe. Ua hōʻike ʻia hoʻi e ʻike koke ʻia nā hopena hoʻomaha o ka lau nahele e ʻae iā ʻoe e hauʻoli i kahi hoʻomaha maikaʻi me ka ʻole o ka ʻeha, ke kaumaha a me ka hopohopo.

10) Hana Anai-Ulcer

Ua hōʻike ʻia kahi haʻawina e loiloi ana i ka hana anti-ulcer o ka methanol extract, methanol fractions a me ka chloroform o nā hua akuamma i nā hakina a me nā extracts o ka lau nahele i hoʻoemi kupaianaha i ka helu ʻai maʻi a me ka nui o ka acidity a me ka hana pepsin.

Akā, ua hoʻokumu ʻia ka hoʻonui ʻana i ka parameter Mucoprotective. ʻO ka waiwai o kēia mea kanu lāʻau e hoʻohui i nā pono olakino he nui i ʻike ʻia no ka mea kanu.