Noopept: Ihe niile I Kwesịrị Ịma

Na-eme ka ọrụ ọgụgụ isi dịkwuo mma

Otu nnukwu ihe akaebe ụlọ ọgwụ na-akwado uru nke Noopept na mpaghara dị iche iche nke ọrụ ọgụgụ isi dị ka ebe nchekwa, mmụta, na ikike iche echiche:

• N'ime ndị ọrịa nwere nsogbu uche nke traumas ma ọ bụ ọrịa ụbụrụ vaskụla kpatara, Noopept kwalitere ọrụ ụbụrụ dị ka egosipụtara site na mmụba alfa na beta-rhythms na electroencephalogram (EEG).
• Nlekọta nke Noopept na dose nke 20 mg kwa ụbọchị maka ọnwa 2 kwalitere ọrụ ọgụgụ isi na ndị ọrịa nwere ọrịa strok ma nwee nnukwu nchekwa.
• N'ọtụtụ ụdị anụmanụ nke ọrịa Alzheimer (AD), Noopept chebere mkpụrụ ndụ ụbụrụ oke megide amyloid beta toxicity (ihe na-akpata AD) site na igbochi mmebi oxidative, igbochi oke calcium, na igbochi apoptosis (ọnwụ cell emebere).
• Nlekọta ọnụ ugboro ugboro nke Noopept na oke na-eme ka mmụta dịkwuo mma ma e jiri ya tụnyere otu dose.
• Na ụdị oke nke ọrịa strok, Noopept gosipụtara ma cognition-eweghachite na akụrụngwa neuroprotective.
• Na nkịtị na Down's syndrome ụbụrụ ụbụrụ mmadụ neurons, Noopept gbochiri oxidative mmebi na apoptosis.
• Na oke mara mma, nchịkwa Noopept mụbara ọrụ ụbụrụ na EEG.
• Noopept nwere ikike ịbawanye ọkwa nke uto uto akwara na ụbụrụ Neurotrophic Factor, nke ejikọtara na mmelite na-adịghị ala ala na ebe nchekwa.
• Noopept nwere ike inye aka melite ọrụ ọgụgụ isi site na ịkwalite akara eletrik n'etiti neurons.
• Noopept na nha 1:1 ma ọ bụ okpukpu iri ka ukwuu pụtara na-ebelata ọkwa Lewy (protein clumps na-akpata ọrịa Parkinson) n'ụbụrụ.
• N'ime ụmụ oke nwere nsogbu mgbakasị ahụ, nchịkwa na-adịghị ala ala nke Noopept mụbara ịdị irè nke ọgwụ anticonvulsant valproate.
• Otu nnyocha kọrọ na Noopept na-arụ ọrụ ya neuroprotective mmetụta site na ya antioxidant na mgbochi mkpali Njirimara.
• N'ime oke, Noopept kwalitere nnyefe nke mgbaàmà akwara na ụbụrụ.
• N'ime ụmụ oke, Noopept gbochiri egbochi mmepe nke nsogbu ọgụgụ isi nke scopolamine kpatara.
• N'ime oke, Noopept tụgharịrị nrụrụ aka site n'ịbawanye ọkwa nke ụbụrụ neurotrophic kpatara (BDNF).
• N'ụdị òké nke ọrịa Alzheimer, Noopept gbochiri ebe nchekwa njọ.
• Nnyocha e mere na-akọ na Noopept nwere ike inye aka gbochie ọrịa Alzheimer site na igbochi nhazi nke protein na-adịghị mma na ụbụrụ yana ibelata ọrụ nke protein kinase-activated mitogen-activated (MAPK).
• N'ime ụmụ oke, ịgba ọgwụ Noopept nkeji 5 tupu ịmụ ihe na-eme ka ebe nchekwa dị ogologo oge dịkwuo mma.
• Na oke nwere ọrịa strok, ọgwụgwọ Noopept belatara mpaghara infarction (anụ ahụ nwụrụ anwụ) na ụbụrụ.
• N'ime oke, nchịkwa Noopept na 5 mg / kg site na injections na-emepụta mmetụta na-eme ka ọgụgụ isi.
• Nlekọta nke 0.5-10 mg / kg nke Noopept na oke kpalitere mmụta otu nnọkọ mgbe otu nchịkwa gasịrị, ebe nchịkwa ugboro ugboro mụbara ikike mmụta nke oke ndị dara ọzụzụ mbụ na ọrụ nkwụsị nke na-agafe agafe (nnwale na-enyocha mmụta na ebe nchekwa) .
• Noopept (GVS-111, N-phenylacetyl-L-prolylglycine ethyl ester) nchịkwa na dose nke 0.5 mg/kg nkeji 15 tupu mmalite nke Morris maze butere ọganihu dị ukwuu na ebe nchekwa ogologo oge.
• N'ime oke nwere mkpakọ nke ụbụrụ ụbụrụ na-akpata, nchịkwa Noopept site na injections na ụzọ ọnụ na-eme ka iweghachite nzaghachi na-adịghị mma.
• Nnyocha cell chọpụtara na Noopept gbochiri neurodegeneration nke glutamate na nrụgide oxidative kpatara.
• N'ime oke ndị nwere nkwarụ ọgụgụ isi n'ihi lobectomy, usoro nke gụnyere iwepụ akụkụ ụbụrụ dum nke ụbụrụ, Noopept kwalitere mweghachi nke mmụta na ebe nchekwa.
• A cell ọmụmụ kọrọ na Noopept kwalite nnyefe nke mgbaàmà n'etiti ụbụrụ mkpụrụ ndụ.

Na-alụso Nchegbu ọgụ

• Ikike na-eme ka ọgụgụ isi nke Noopept na-emepụtakwa mmetụta mgbochi nchegbu dịka ọmụmụ si kwuo:
• Nlekọta Noopept n'ime ndị ọrịa nwere nhụsianya dị nro na-ebelata ike ọgwụgwụ, nchekasị, na mgbakasị ahụ.
• N'ime ndị ọrịa nwere ụkwara nta ume iku ume ọhụrụ, ọgwụgwọ Noopept belatara ngosipụta nke nchegbu.
• N'ime oke, nchịkwa Noopept jikọtara ya na mmụba nke ọrụ locomotor na ule elu plus-maze, na-atụ aro mmetụta mgbochi nchegbu.
• Ọchịchị Noopept gbakwara omume nyocha nke oke na-anwale ule oghere, nke na-egosi mbelata nchekasị.
• N'ime ụmụ oke, nchịkwa nke Noopept mepụtara mgbanwe nke ọkwa nchegbu.
• N'ime oke, Noopept belatara omume enweghị enyemaka mmụta.
• N'ime ụmụ oke sitere na ụdị dị iche iche, Noopept belatara ọkwa nrụgide dịka ọ na-egosipụta site na mmụba nke mmeghachi omume na-ezere na nyocha nke na-akpata nchekasị.
• N'ime oke ndị dị afọ 4 ụbọchị, Noopept tụgharịrị ihe ịrịba ama nke nrụgide nke corticotropin na-ahapụ hormone (CRH).
• N'ime ụdị oke oke agbakwunyere, nchịkwa Noopept na 1 mg kwa kilogram kwa ụbọchị na-emepụta mmetụta mgbochi nchegbu na ụbọchị 7th.

Na-eme ka ọnọdụ

Noopept nwekwara ike inye aka melite ọnọdụ, na-eme ka ọ bụrụ nhọrọ ọgwụgwọ maka ụfọdụ nsogbu ahụike uche:

• Ọchịchị Noopept ogologo oge (ụbọchị 21) kpochapụrụ ihe ngosi nke enweghị enyemaka mmụta ma e jiri ya tụnyere ọgwụ mgbochi nchegbu Afobazol.
• Ọchịchị na-adịghị ala ala (ụbọchị 28, 0.5 mg / ụbọchị site na injections) nke Noopept na-eme ka omume dịkwuo mma site n'ịbelata ọrụ nke kinases na-akpata nchekasị (tinye aka na nsogbu uche) na ịba ụba nke BDNF.

Na nchịkọta, Noopept bụ onyinye na-ekwe nkwa nke nwere uru maka ọrụ ọgụgụ isi, nchekasị, na ọnọdụ. Aogubio bụ ebe a tụkwasịrị obi nke Noopept dị elu na ihe ndị ọzọ na-arụ ọrụ ọgwụ, na-eme ka ndị ahịa nwee ike ịnweta ngwọta a pụrụ ịdabere na ya, dị irè maka mkpa ahụike na ahụike ha. Ma ejiri ya na mgbakwunye, ọgwụ ọgwụ, ma ọ bụ ngwa ndị ọzọ, Noopept nwere ikike ime mgbanwe bara uru na ndụ ndị ọrụ. Ka ọchịchọ nke ndị na-emewanye ihe nlebara anya na-aga n'ihu, AoguBio nọgidere na-agba mbọ ịnye ngwaahịa ọhụrụ iji gboo mkpa na-agbanwe agbanwe nke ndị ahịa anyị.

Ederede edemede:Miranda Zhang