Ectoine A na-akpọkwa tetrahydromethylpyrimidinecarboxylic acid. Ectoin na-echebe nje bacteria halophilic pụọ na mmerụ ahụ. Ọ nwere ọrụ abụọ bụ isi: 1) Moisturizing: Ọ bụ ihe dị mkpa maka idowe nguzozi nrụgide osmotic. Ọdịdị molekụla ya pụrụ iche nwere ikike mgbagwoju anya nke molekul mmiri, nke nwere ike ime ka mkpụrụ ndụ ahụ na-edozi mmiri na-enweghị ihe ọ bụla ma bụrụ ihe magburu onwe ya. 2) Mmezi: Ectoin nwere ike iguzogide mmebi nke ụzarị ultraviolet na akpụkpọ ahụ ma rụkwaa mmebi DNA cell nke ụzarị ultraviolet kpatara.
Usoro kemịkalụ nke Ectoine bụ 2-methyl-1,4,5,6,-ectoine-4-carboxylic acid, nke a makwaara dị ka ectoine, nke bụ ụdị peptide ọhụrụ nwere soluble mmiri nke achọpụtara na 1985. Zwitterionic amino acid derivatives. Na 1985, Galinski bu ụzọ chọpụta ma kewapụ ectoine dịpụrụ adịpụ site na nje bacteria halophilic site na resonance magnetik na spectrometry mass. N'okpuru nnukwu nnu nnu, Ectoine na-arụ ọrụ dị ka nrụgide osmotic na-akwụ ụgwọ solute ma na-akwakọba n'ọtụtụ buru ibu na ụfọdụ nje bacteria halophilic iji guzogide mgbanwe na nrụgide osmotic dị elu nke gburugburu ebe obibi.
Ịrụ ọrụ na ọrụ
Ectoine bụ ihe okike na nke dị irè ihe ịchọ mma na-arụ ọrụ. N'ihi na ọ nwere ọtụtụ ọrụ nchebe cell, enwere ike iji ya na ihe ịchọ mma dị iche iche nwere ọrụ dị iche iche. Ectoine nwere moisturizing, antioxidant, photoaging, nchebe anyanwụ na ọrụ ndị ọzọ. Ezigbo ihe na-edozi ahụ: Iji Ectoine na-edozi akpụkpọ ahụ nwere ike ibelata mmebi akpụkpọ ahụ nke akpịrị ịkpọ nkụ kpatara; Otu molekul Ectoine nwere ike gbakwụnye mmiri anọ ma ọ bụ ise ma hazie mmiri efu dị n'ime mkpụrụ ndụ. E jiri ya tụnyere glycerin, ectoine na-eme ka akpụkpọ ahụ dịkwuo mma. Ihe data dị mkpa na-egosi na Ectoine nwere ike na-aga n'ihu na-emeziwanye moisturize anụ ahụ na ike ijide mmiri n'oge oge ngwa.
Ike ijide mmiri nke akpụkpọ ahụ agaghị ebelata ozugbo ọ kwụsịrị iji ya. Mgbe otu izu kwụsịrị, ikike ijide mmiri nke akpụkpọ ahụ ka dị elu karịa nke otu njikwa. Ịdị irè Antioxidant: Nnwale ụlọ ọgwụ egosila na ectoin nwere ike igbochi ike ọgwụgwụ nke ikike antioxidant nke mkpụrụ ndụ na afọ ma nwee ụfọdụ ikike antioxidant. Data nnwale na-egosi na ngwakọta agwakọta nke 0.1mMEctoine, ọgwụ 0.5mM na 1.5mM mannitol nwere ike belata nkwụsịtụ nke DNA glial cell DNA n'okpuru isi iyi ọkụ 400-800nm, belata ike nke mmeghachi omume oxidation ROS, si otú ahụ belata oxidation ọkụ. akpụkpọ ahụ. imerụ. Nchekwa usoro mgbochi mkpụrụ ndụ Langerhans dị na epidermis na-arụ ọrụ dị mkpa n'ime usoro ahụ ji alụso ọrịa ọgụ akpụkpọ ahụ, mana ha na-enwe mmetụta dị ukwuu na nrụgide ultraviolet.
Ectoine nwere ike igbochi ọnụ ọgụgụ nke mkpụrụ ndụ Langerhans site na radieshon ultraviolet belata, na-ekwe ka usoro ahụ ji alụso ọrịa ọgụ nọgide na-arụ ọrụ nke ọma. Nchedo site na fotoaging na anwụ na-echebe ịka nká akpụkpọ ahụ abụghị nanị ihe si na njedebe nke oge, ma otu n'ime ihe ndị dị mkpa dị na mpụga bụ ụzarị ultraviolet, karịsịa UVA (320-400nm). N'ime band ultraviolet dum, UVA nwere ogologo wavele ogologo na ume kacha ala. Agbanyeghị, n'adịghị ka UVB, mgbanwe nke ọdịnaya UVA na ìhè anyanwụ na-emetụta obere oge site na latitude, oge, ihu igwe na oge.
Ya mere, ndị UVA ikpughe kwa ụbọchị na kwa afọ Doses na-fọrọ nke nta ka ofu na-anọgide na-agbakọta na nnukwu ichekwa ná ndụ anyị niile.
Ojiji:
Ecdoine nwere moisturize na ịrụzi ọrụ ma na-eji ọtụtụ ebe na ubi nke anụ ahụ ngwaahịa na-emeziwanye ụda akpụkpọ.
Usoro nkwadebe
Ka ọ dị ugbu a, a na-ewepụta Ectoine n'ụzọ bụ isi site na ụdị halophile. Emebela teknụzụ ụlọ ọrụ nke iji halobacteria na-emepụta ectoine. Nkà na ụzụ a na-eji nnukwu mkpokọta glycerol dị ka isi iyi carbon ma jiri usoro a na-akpọ "mmiri ara ehi nje". Usoro "mmiri mmiri ara nke nje" bụ na ụdị nje nje halophilic na-eto ma na-amụba n'ime mmiri omenala nnu dị elu (dị ka 100g/L). Ectoine na-eje ozi dị ka solute nkwụghachi ụgwọ nrụgide osmotic ma na-akwakọba n'ọtụtụ buru ibu na ụfọdụ nje bacteria halophilic iji guzogide gburugburu mpụga.
Mgbanwe na nrụgide osmotic dị elu; mgbe ntinye uche nke cell rutere n'ogo kachasị elu, ntinye nnu na-adaba na mberede site na nnukwu ntinye uche (dị ka 100g / L) na obere ntinye uche (dị ka 20g / L). Mgbe hypotonicity kpaliri, nje bacteria nwere ike ozugbo Ectoine kwakọbara n'ime sel na-ahapụ ya na mpụga ụwa iji zere mgbasawanye cell ma ọ bụ mmebi n'ihi mbelata nrụgide osmotic gburugburu ebe obibi. N'ikpeazụ, enwere ike sachaa Ectoine site na nzacha, crystallization na teknụzụ ndị ọzọ iji nweta Ectoine. Edemede na-egosi na iji usoro a dị n'elu, enwere ike nweta ihe dịka 2g Ectoine kwa liter nke mmiri ọdịnala kwa ụbọchị. Bioactive Ectoine bụ ihe na-echebe mkpụrụ ndụ sitere n'okike, ihe nrụpụta amino acid nke nje bacteria bi na ọnọdụ gburugburu ebe obibi siri ike na-emepụta. A na-eji Ectoine dị ka ihe ndakọrịta osmoregulation solute iji mee ka hydration dịkwuo elu n'elu anụ ahụ ma mee ka oyi akwa lipid guzosie ike, a na-ejikwa ya na nlekọta anụ ahụ. Ectoine nwere ezigbo profaịlụ nchekwa yana enwere ike iji ya mụọ rhinitis nfụkasị ahụ.
Kedu ihe ndị ọzọ Ectoin na-arụ ọrụ nke ọma?
Tụlee ectoin dị ka UN nke ihe nlekọta anụ ahụ-ọ na-egwuri egwu nke ọma na ihe fọrọ nke nta ka ọ bụrụ ndị ọzọ niile na-arụ ọrụ. "Ọ dị mma ijikọta ya na ihe ndị nwere ike ịkpasu iwe dị ka retinoids na hydroxy acids," ka Dr. King na-ekwu, dị ka ectoin si hydrating na mmetụta nchebe pụrụ inye aka ịlụso ọgụ na ibelata ohere nke iwe ma ọ bụ ọbara ọbara ọ bụla.2 "Uru nke ectoin nwekwara ike ịbawanye uru site na ihe ndị nwere ihe na-eme ka ahụ dị nro, dị ka hyaluronic acid na glycerin, ma ọ bụ ihe ndị na-enye aka na-ewusi ihe mgbochi akpụkpọ ahụ ike, dị ka ceramides na peptides. Ndị a na-arụkọ ọrụ nke ọma iji chebe akpụkpọ ahụ na ịkwalite hydration," Dr. Palm na-agbakwụnye.
Kedu onye kwesịrị ịtụle iji Ectoin?
Nke a bụ ụfọdụ akụkọ na-akpali akpali-ma ndị dọkịta dermatologists anyị na-egosi na eziokwu ahụ bụ na ọ fọrọ nke nta ka ọ bụrụ onye ọ bụla na onye ọ bụla na-anabata ectoin nke ọma, n'agbanyeghị ụdị akpụkpọ ahụ gị, n'ihi ya, ị gaghị echegbu onwe gị banyere mmetụta ndị dị n'akụkụ (n'agbanyeghị na ọ kacha mma). ma ọ bụrụ na ị na-alụ ọgụ akọrọ na/ma ọ bụ akpụkpọ ahụ mgbakasị ahụ). Nke a na-ekwu, ihe nfụkasị ahụ na ihe ahụ ka nwere ike ime, ya mere ọ kacha mma iji ngwaahịa nlekọta anụ ahụ ọhụrụ mee ule patch.
Pls kpọtụrụ Alisa site nasales02@imaherb.commaka ọnụahịa na nkọwa COA
Oge nzipu: Mar-29-2024
