N-Acetylcysteine: Njira Yachilengedwe Yothetsera Thupi
Kuchotsa poizoni kwakhala nkhani yotchuka kwambiri m'zaka zaposachedwa, pamene anthu amafunafuna njira zochotsera poizoni m'thupi mwawo ndikuwongolera thanzi lawo lonse. Ngakhale pali njira zambiri ndi mankhwala omwe alipo pamsika, mankhwala amodzi achilengedwe omwe apeza chidwi ndi N-Acetylcysteine (NAC). Gululi, lochokera ku amino acid L-cysteine, latamandidwa chifukwa cha mphamvu zake zochotsa poizoni komanso mapindu ambiri azaumoyo.
NAC ndi antioxidant wamphamvu yemwe amathandizira kuletsa ma radicals aulere m'thupi, kuteteza kuwonongeka kwa ma cell ndi kupsinjika kwa okosijeni. Pochita izi, imathandizira ntchito ya chiwindi, yomwe ndi yofunika kwambiri kuti iwonongeke. Chiwindi chimagwira ntchito yofunika kwambiri pochotsa poizoni, kuzisefa kuchokera m'magazi ndikuzisintha kukhala zinthu zosavulaza zomwe zimatha kuchotsedwa kudzera mkodzo kapena bile. NAC imathandizira izi popititsa patsogolo kupanga glutathione, antioxidant wofunikira komanso detoxifier yomwe imagwira ntchito yofunika kwambiri pakuchotsa chiwindi.
Kuphatikiza apo, NAC yawonetsa zotsatira zabwino poteteza ku kuwonongeka kwa chiwindi chifukwa cha poizoni monga mowa, zitsulo zolemera, ndi mankhwala ena. Kafukufuku wapeza kuti zingathandize kupewa kuvulala kwa chiwindi ndikulimbikitsa kusinthika kwa maselo owonongeka a chiwindi. Izi zimapangitsa NAC kukhala wothandizana nawo wofunikira pakusunga thanzi lachiwindi ndikuthandizira njira zachilengedwe zochotseratu poizoni m'thupi.
Kuphatikiza pa zotsatira zake zowonongeka, NAC imaperekanso maubwino ena azaumoyo. Zapezeka kuti zimathandizira thanzi la kupuma mwa kupatulira ndi kumasula ntchofu, zomwe zimapangitsa kuti zikhale zosavuta kuchotsa mpweya. Izi zimapangitsa kuti NAC ikhale yopindulitsa makamaka kwa anthu omwe ali ndi vuto lopumira, monga matenda osachiritsika a m'mapapo (COPD) ndi mphumu.
Kuphatikiza apo, NAC yawonetsa zotsatira zabwino zamaganizidwe komanso magwiridwe antchito anzeru. Itha kulimbikitsa ma neurotransmitters ofunikira monga glutamate ndi dopamine, omwe amalumikizidwa ndi kuwongolera kwamalingaliro ndi magwiridwe antchito anzeru. Kafukufuku wambiri wasonyeza kuti NAC ikhoza kukhala yothandiza poyang'anira mikhalidwe monga kuvutika maganizo, bipolar disorder, ndi schizophrenia. Kuphatikiza apo, NAC yapezeka kuti imateteza ku kuwonongeka kwa ubongo komwe kumachitika chifukwa cha kupsinjika kwa okosijeni, ndikupangitsa kuti ikhale yochizira matenda a neurodegenerative monga Alzheimer's ndi Parkinson's.
Ngakhale zili ndi zabwino zambiri, ndikofunikira kudziwa kuti NAC iyenera kugwiritsidwa ntchito motsogozedwa ndi akatswiri azachipatala. Ngakhale kuti nthawi zambiri zimakhala zotetezeka kwa anthu ambiri, zimatha kuyanjana ndi mankhwala ena ndipo zingayambitse zotsatira zake monga nseru, kutsegula m'mimba, kapena kupweteka kwa mutu pamene agwiritsidwa ntchito mopitirira muyeso kapena mlingo waukulu.
Pomaliza, N-Acetylcysteine ndi mankhwala achilengedwe omwe amapereka mphamvu zochotseratu poizoni pamodzi ndi miyandamiyanda yazaumoyo. Pothandizira kugwira ntchito kwa chiwindi, kulimbikitsa chitetezo cha mthupi, komanso kulimbikitsa kuchotsa poizoni woopsa, NAC ikhoza kuthandiza anthu kukhala ndi thanzi labwino komanso thanzi. Komabe, ndikofunikira kukaonana ndi katswiri wazachipatala musanaphatikizepo NAC muzochita zanu kuti muwonetsetse kuti ikugwiritsidwa ntchito moyenera komanso moyenera. Monga momwe zilili ndi zakudya zina zilizonse, ndi bwino kumangotengera thanzi lanu ndikusankha zochita mwanzeru.
Mafotokozedwe Akatundu
N-acetyl cysteine (NAC) imachokera ku amino acid L-cysteine. Ma amino acid ndizomwe zimamanga mapuloteni. NAC ili ndi ntchito zambiri ndipo ndi mankhwala ovomerezeka a FDA.
N-acetyl cysteine ndi antioxidant yomwe ingathandize kupewa khansa. Monga mankhwala, amagwiritsidwa ntchito ndi othandizira azachipatala pochiza poizoni wa acetaminophen (Tylenol). Zimagwira ntchito pomanga mitundu yapoizoni ya acetaminophen yomwe imapangidwa m'chiwindi.
Anthu nthawi zambiri amagwiritsa ntchito N-acetyl cysteine kutsokomola ndi matenda ena am'mapapo. Amagwiritsidwanso ntchito pa chimfine, diso louma, ndi zina zambiri, koma palibe umboni wabwino wa sayansi wochirikiza zambiri mwa izi. Palibenso umboni wabwino wochirikiza kugwiritsa ntchito N-acetyl cysteine pa COVID-19.
N-Acetyl-L-Cysteine ndi amino acid, akhoza kusandulika kuchokera ku thupi la methionine, cystine akhoza kusandulika wina ndi mzake. N-Acetyl-l-cysteine ingagwiritsidwe ntchito ngati mucilagenic wothandizira. Ndi oyenera kupuma kutsekeka chifukwa cha kuchuluka kwa phlegm kutsekeka. Kuphatikiza apo, itha kugwiritsidwanso ntchito pochotsa poizoni wa acetaminophen.
Ntchito
N-Acetyl-L-Cysteine ndi amino acid, akhoza kusandulika kuchokera ku thupi la methionine, cystine akhoza kusandulika wina ndi mzake. N-Acetyl-l-cysteine ingagwiritsidwe ntchito ngati mucilagenic wothandizira. Ndi oyenera kupuma kutsekeka chifukwa cha kuchuluka kwa phlegm kutsekeka. Kuphatikiza apo, itha kugwiritsidwanso ntchito pochotsa poizoni wa acetaminophen.
