Aogubio nisosiyete kabuhariwe mu gukora no gukwirakwiza ibintu bikora ibya farumasi, ibikoresho fatizo, ibimera bivamo ibimera nintungamubiri kugirango habeho inyongeramusaruro zabantu. Ibicuruzwa byacu bikoreshwa mu bya farumasi n’imiti, ibiryo, intungamubiri n’amavuta yo kwisiga. Kimwe mubicuruzwa byacu bizwi cyane niCDP-Choline , bizwi kandi nka CITICOLINE. CDP-Choline ni ifumbire ya nootropique ikora nka prodrug ya choline na uridine, igaha umubiri iyi molekile ya ngombwa iyo ifashwe mu kanwa.
CDP-Choline ni iki?
Citicoline, izwi kandi nka CDP-choline cyangwa cytidine diphosphate-choline, ishyirwa mu rwego rwa nootropique kubera ingaruka zayo zo kongera ubwenge.
Nibibanziriza choline na cytidine.
Choline na cytidine byombi birakenewe muguhuza ibice byingenzi bigize selile, cyane cyane mubwonko.
Inyungu 10 zemejwe na Citoline (CDP-Choline)
Ubushakashatsi bwinshi bwerekanye ko CDP-choline ikora neza kuruta fosifatiidiloline (PC) mu gukumira ubumuga bwo kwibuka. Byongeye kandi, byagaragaye ko byongera synthesis ya PC mu bwonko, bityo bikagira uruhare mu ngaruka zayo. Mugihe CDP-Choline igereranywa mubikorwa na Alpha-GPC, itanga inyungu zuzuye kubikorwa byubwenge.
- Citoline Yongera Kwibuka
Citicoline yerekanwe kunoza kwibuka.
Ibi biterwa ahanini nuruhare rwarwo mu kongera urugero rwa acetylcholine, neurotransmitter ya ngombwa mu kwibuka no kwiga.
Ubushakashatsi bwinshi bwerekanye ingaruka zongera kwibuka Citicoline.
Mu bushakashatsi bumwe, abantu bakuze bafite ubumuga bwo kwibuka butajyanye n'imyaka bafashe Citicoline mu byumweru 12.
Abitabiriye ubushakashatsi bakiriye mg 1000 cyangwa mg 500 za Citicoline buri munsi.
Babonye iterambere mubyibuka nyuma yo kubifata.
Abashakashatsi basuzumye kandi ingaruka za Citicoline ku bagore bakuze bafite ubuzima bwiza.
Abagore bafashe mg 250 cyangwa 500 mg buri munsi ya Citicoline muminsi 28.
Byatumye habaho iterambere ryinshi mumikorere yubwenge, harimo no kwibuka.
Ubwanyuma, itsinda ryabashakashatsi ryasesenguye ubushakashatsi butandukanye ku ngaruka za Citicoline ku gukira indwara yimitsi.
Bashoje bavuga ko abarwayi bakiriye Citicoline bagaragaje iterambere mu kwibuka no mu mikorere.
Ubu bushakashatsi, hamwe nibindi, butanga ibimenyetso bifatika byingaruka zongera kwibuka Citicoline.
- Citicoline itezimbere kwibanda no kwitabwaho
Citicoline ishyigikira synthesis yingirakamaro ya neurotransmitter, nka acetylcholine na dopamine, bigira uruhare runini mubitekerezo no kwibanda.
Mugukomeza kuboneka kwa neurotransmitter, Citicoline ifasha kunoza ibitekerezo no kwibanda.
Ubushakashatsi bwasanze ibi ari ukuri.
Ubushakashatsi bwinshi bwerekanye ko inyongera ya Citoline ishobora gufasha kongera ibitekerezo, kwibanda, no kwibanda.
Mu bushakashatsi bumwe, abagore bakuze bafite ubuzima bwiza bafashe mg 250-500 mg buri munsi ya Citicoline muminsi 28.
Abashakashatsi basanze abo bagore bagize iterambere ryinshi mubikorwa byo kwitabwaho.
Mu bundi bushakashatsi, abashakashatsi basanze abantu bakuru bafite ubuzima bwiza bafashe Citicoline mu byumweru bitandatu bagize iterambere mu kwitabwaho no mu mikorere y’ubwenge.
Hanyuma, ubushakashatsi bwateganijwe, buhumye-buhumyi, ubushakashatsi bugenzurwa na platbo bwarebye ingaruka za Citicoline ku mikorere yubwenge mu bakorerabushake bafite ubuzima bwiza.
Abashakashatsi basanze abitabiriye kwakira Citicoline bagaragaje iterambere ryinshi mu kwitabwaho, kwibuka mu kazi, no kumenya guhinduka.
Urebye ubu bushakashatsi bwose, biragaragara neza ko Citicoline ishobora kugirira akamaro cyane abanyeshuri, abanyamwuga, cyangwa umuntu wese ushaka kunoza ibitekerezo byabo hamwe nibikorwa rusange byubwenge.
- Citicoline Ni Neuroprotective
Citicoline izwiho kuba neuroprotective.
Irinda ingirabuzimafatizo zo mu bwonko kwangirika no kwangirika.
Irabikora ikomeza ubusugire bwimikorere ya selile, kugabanya stress ya okiside, no kugabanya umuriro mubwonko
Izi ngaruka zigira uruhare mubuzima bwubwonko muri rusange. Barashobora kandi kurinda kugabanuka kwubwenge hamwe nubuzima bwa neurodegenerative.
Ubushakashatsi bwinshi bwerekanye ingaruka za neuroprotective ya Citicoline, cyane cyane mugihe cyubwonko bwa ischemic, gukomeretsa ubwonko, no kugabanuka kwubwenge.
Abashakashatsi basanze Citicoline ishobora gufasha kugabanya urugero rwa glutamate, neurotransmitter ishimishije. Glutamate irashobora kwangiza ubwonko iyo ihari kubwinshi.
- Citicoline ifasha mugukiza indwara yubwonko
Ubushakashatsi bwerekanye ko Citicoline ishobora gufasha mugikorwa cyo gukira nyuma yubwonko.
Irabikora mukuzamura ubwonko bwa plastike, guteza imbere imikurire mishya mishya, no kugabanya gucana no kwangiza imitsi.
Nkigisubizo, gikunze gukoreshwa nkubuvuzi bujyanye no kuvura indwara zisanzwe.
Citoline isa nkaho ifasha cyane cyane abarwayi barwaye indwara yubwonko.
Ischemic stroke ibaho mugihe amaraso atembera mubwonko ahagaritswe, bigatuma habura ogisijeni nintungamubiri. Ibi birashobora noneho gutera urupfu no kwangirika kwimitsi.
Isesengura ryakozwe ku bigeragezo by’amavuriro ryarebye ingaruka za Citicoline mu bwonko bukabije.
Abashakashatsi basanze abarwayi bakiriye Citicoline bagize uburambe mu mikorere no mu bwenge.
Ubundi bushakashatsi bwakozwe bwerekanye uruhare rwa Citicoline muri neuroprotection na neurorepair muri stroke ischemic.
Abanditsi banzuye bavuga ko muri rusange Citicoline yihanganirwa kandi ko ishobora kuzamura imikorere n’imikorere y’abarwayi ba stroke. Ibi byari ukuri cyane mugihe byatanzwe hakiri kare mugikorwa cyo kuvura.
- Citicoline Itezimbere Imyitwarire no Gutera Imbere
Citicoline yahujwe no kwiyongera kwa dopamine, neurotransmitter ijyanye no gushishikara, kwishimira, no guhemba.
Ingaruka zirashobora gufasha kunoza imyumvire, gushishikara, no kumererwa neza muri rusange.
Kubera iyo mpamvu, ubushakashatsi bumwe bwerekanye ko Citicoline igira ingaruka zisa na antidepressant.
Mu bushakashatsi bumwe, abashakashatsi bakoze ubushakashatsi ku ngaruka ziterwa na Citicoline ku myumvire n'imbaraga zo mu mutwe.
Ikigeragezo cyarimo abantu 60 bitabiriye ubuzima bwiza. Bakiriye Citicoline (250 mg / kumunsi cyangwa 500 mg / kumunsi) cyangwa umwanya wibyumweru bitandatu.
Abitabiriye amahugurwa bakiriye Citicoline bavuze ko bateye imbere mu myumvire yabo n'imbaraga zo mu mutwe.
- Citoline itezimbere imyigire
Citoline yerekanwe kunoza imyigire.
Irabikora iteza imbere ibintu bitandukanye byimikorere yubwenge, harimo kwibuka, kwitondera, na neuroplastique.
Mu bushakashatsi bumwe, abashakashatsi bakoze ubushakashatsi ku ngaruka za Citicoline ku myigire no kwibuka ku bantu bakuru.
Uru rubanza rwarimo abantu bakuru 60 bafite ubuzima bwiza. Bakiriye Citicoline (250 mg / kumunsi cyangwa 500 mg / kumunsi) cyangwa umwanya wa 28.
Abashakashatsi basanze abitabiriye kwakira Citicoline bagaragaje imikorere inoze mu mirimo itandukanye yo kumenya, harimo n’ibijyanye no kwiga.
- Citicoline Yongera Acetylcholine mu bwonko
Acetylcholine ningirakamaro ya neurotransmitter igira uruhare mubintu bitandukanye byimikorere yubwenge, harimo kwiga, kwibuka, no kwitaho.
Iyo Citicoline yinjiye kandi igahinduka, igabanywamo choline.
Choline irashobora noneho kurenga inzitizi yubwonko bwamaraso ikinjira mubwonko.
Iyo choline imaze kwinjira mu bwonko, ikoreshwa mu guhuza acetyloline.
Kubera iyo mpamvu, Citicoline yerekanwe kongera urugero rwa choline na acetyloline mu bwonko. Ibi noneho bigira uruhare mugutezimbere imikorere yubwenge.
Ubushakashatsi bwinshi bwerekanye ko inyongera ya Citicoline ishobora gutuma acetyloline yiyongera mu bwonko.
Mu bushakashatsi bumwe, abashakashatsi bakoze ubushakashatsi ku ngaruka za Citicoline kuri cholinergic neurotransmission.
Ibisubizo byerekanye ko Citicoline yongereye irekurwa rya acetyloline muri hippocampus, akaba ari agace k’ubwonko gakomeye mu kwiga no kwibuka.
Ubundi bushakashatsi bwarebye ingaruka za Citicoline ku kwerekana ibimenyetso bya plastike yo mu bwonko.
Abanditsi basanze Citicoline yatumye ubwonko bwa acetyloline bwiyongera mu bwonko.
Ubu ni bubiri gusa mubushakashatsi bwinshi bwerekana ko inyongera ya Citicoline ishobora kongera urugero rwa acetyloline mu bwonko.
- Citicoline igabanya gucana mubwonko
Gutwika bigira uruhare runini mu iterambere no gutera imbere kwindwara zitandukanye zifata ubwonko. Ibi birimo indwara ya Alzheimer, indwara ya Parkinson, na stroke.
Ariko Citicoline yerekanwe ko ifite imiti igabanya ubukana, kandi irashobora gufasha kugabanya ubwonko mu bwonko.
Kurugero, Citicoline igabanya cyane umusaruro wa cytokine itera umuriro mubwonko.
Mu bushakashatsi bumwe, abashakashatsi basuzumye ingaruka za Citicoline ku ihungabana rya okiside no gutwikwa mu buryo bwimbeba y’indwara ya Alzheimer.
Abanditsi basanze Citicoline yagabanije guhagarika umutima no gutwika mu bwonko. Uku kugabanuka kwumuriro byajyanye no kunoza imikorere yubwenge mumbeba.
Mugabanye ubwonko bwubwonko, Citicoline irashobora gufasha kubungabunga ubuzima bwubwonko, kandi igafasha kwirinda indwara zifata ubwonko.
- Citicoline Yongera Ubwonko Bwubwonko
Ubwonko bwubwonko nubushobozi bwubwonko bwo guhinduka no guhuza nibisubizo bishya.
Ubwonko bwa plastike bwubwonko bugira uruhare runini mugushinga amasano mashya hagati ya neuron (synaptogenezi) no gukura kwa neuron nshya (neurogenezi).
Synaptogenezi na neurogenezi byombi ni ngombwa mu kwiga, kwibuka, no gukira ibikomere byo mu bwonko.
Citicoline yerekanwe mu kongera ubwonko bwa plastike, synaptogenezi na neurogenezi.
Mu bushakashatsi bumwe, abashakashatsi bakoze ubushakashatsi ku ngaruka za Citicoline ku kwerekana ibimenyetso bya plastike yo mu bwonko mu buryo bw'imbeba y'imitsi.
Ibisubizo byerekanye ko Citicoline yatumye habaho kwiyongera kwa poroteyine zijyanye na plastike hamwe n’ibintu bikura, nka BDNF na NGF.
Ubundi bushakashatsi bwerekanye ko Citicoline yongerera ubwonko ubwonko kandi igatera gukira nyuma yubwonko.
- Citicoline Ifasha Kugabanuka Kumenya, Ubumuga bworoheje bwubwenge, nindwara ya Alzheimer
Kugabanuka kwubwenge kurangwa no kugabanuka gahoro gahoro mumikorere yo mumutwe, harimo kwibuka, kwitondera, hamwe nubushobozi bwo gukemura ibibazo.
Citicoline yagaragaye ko idindiza igabanuka ry’ubwenge, cyane cyane ku bantu bageze mu za bukuru ndetse n’ababa barwaye indwara zifata ubwonko nk’indwara ya Alzheimer
Ubushakashatsi bwinshi bwerekanye ibyiza bya Citicoline mugutinda kugabanuka kwubwenge.
Ubushakashatsi bumwe bwarebye ingaruka ndende za Citicoline ku barwayi bageze mu zabukuru bafite ubumuga buke bwo kumenya.
Abashakashatsi basanze amezi 9 y’inyongera ya Citicoline yazamuye imikorere y’ubwenge muri aba barwayi.
Ubundi bushakashatsi bwakoze ubushakashatsi ku ngaruka za Citicoline ku kugabanuka kwubwenge ku barwayi barwaye Alzheimer.
Ikigeragezo cyerekanye ko abarwayi bakiriye Citicoline amezi 12 bahuye n’igabanuka ryihuse ryimikorere yubwenge.
Hanyuma, isuzuma rifatika ryasuzumye imikorere ya Citicoline mu kuvura imvururu zishingiye ku myumvire no mu myitwarire ku barwayi bageze mu zabukuru.
Abanditsi banzuye bavuga ko Citicoline yerekanye inyungu zimwe na zimwe mu kuzamura ibimenyetso by’ubwenge n’imyitwarire muri aba barwayi.
Ubushobozi bwa Citicoline bwo kugabanya umuvuduko wubwenge bushobora guterwa nuburyo bwinshi. Irashobora kongera umusaruro wa neurotransmitter, igashyigikira ubwonko bwa selile ubwonko, kongera ubwonko bwubwonko, no kugabanya uburibwe.
IwacuCDP Choline inyongera ziraboneka muburyo butandukanye, harimo capsules na powder, bituma abakiriya bacu bahitamo uburyo bworoshye kubyo bakeneye. Waba uri umuguzi ushaka inyongera yizewe yubwenge, cyangwa ubucuruzi bwimiti cyangwa intungamubiri zishaka ibikoresho fatizo byiza, CDP-Choline ya Aogubio niyo ihitamo neza.
Nibihe biribwa nshobora kubona choline?
Ushobora kuba umaze kurya ibiryo byinshi birimo choline. Choline irashobora kuboneka mubiribwa bitandukanye harimo:
- Ibirayi.
- Ibishyimbo, imbuto n'imbuto.
- Ibinyampeke.
- Inyama, inkoko n'amafi.
- Amata n'amagi.
- Imboga nka broccoli na kawuseri.
Muri make, CITICOLINE ya Aogubio ninyongera ikomeye kandi ifatika yo gushyigikira ubuzima bwimikorere nibikorwa. Hamwe na hamwe yihariye ya choline na uridine, itanga inyungu zuzuye zo kwibuka, kwiga, hamwe nubuzima bwubwonko muri rusange. Waba ushaka kuzamura imikorere yawe yo kumenya cyangwa ukaba ushaka ibikoresho byiza byo mu rwego rwo hejuru kubicuruzwa byawe, ibya AoguBioCDP-Choline ni igisubizo cyiza kuri wewe. Inararibonye imbaraga za CITICOLINE hanyuma ujyane ubuzima bwawe bwubwenge kurwego rukurikira hamwe na Aogubio.
Kwandika ingingo: Miranda Zhnag
Igihe cyo kohereza: Mutarama-17-2024
