N-acetylneuraminic asidhi , inozivikanwawo se sialic acid, ndeyekungoitika carbohydrate molecule inowanikwa mune dzakasiyana siyana biological system. Inotamba zvakakosha mumabasa emasero uye ine akati wandei maapplication mundima dzakasiyana.
Sialic asidhi ipfumbamwe-kabhoni shuga asidhi uye yakabva kune neuraminic acid. Inowanzo kuwanikwa kumagumo ekunze eglycans (oligosaccharide maketani) akasungirirwa kumapuroteni kana lipids pamasero. Aya ma glycans, anozivikanwawo sealylated glycans, anobatanidzwa mune akakosha maseru maitiro sekuzivikanwa kwesero-sero, kusaina, uye mhinduro dzemuviri.
Ndeapi Mabasa eN-acetylneuraminic Acid?
- Kuzivikanwa kweSerura: Sialic acid-ine glycans inoita semacherechedzo ekucherechedzwa pane esero. Ivo vanobatanidzwa mumaitiro akasiyana-siyana senge sero adhesion, immune cell kuzivikanwa, uye kusiyanisa.
- Immune Mhinduro: Sialic acid inoita basa rakakosha mukugadzirisa maitiro ezvirwere zvemuviri. Inogona kuita sechinhu chinogamuchira utachiona, ichibatsira kutanga maitiro ekudzivirira zvirwere kubva kune ma microorganisms anopinda. Pamusoro pezvo, sialic acid shanduko pamasoja ekudzivirira chirwere anobatsira pakuita kwavo mukudzivirira kwekudzivirira.
- Serura Masaini:Sialic acid inogona kutora chikamu mumasero ekusaina nzira uye kudzora akakosha maserura maitiro akadai sekuwedzera kwesero, kusiyanisa, uye apoptosis.
- Kudzivirirwa uye Lubrication: Sialic acid inobatsira kuchengetedza masero kubva kune zvinokuvadza nekuita sechivharo chemuviri. Inobatsirawo pakuzora kwenzvimbo dzemucosal, dzakadai sedziri mumaturakiti ekufema uye emudumbu.
Ndeapi maApplication eN-acetylneuraminic Acid?
- Indasitiri yemishonga: Sialic acid-based compounds ine mishonga inogona. Semuyenzaniso, sialic acid derivatives yakatariswa kune yavo antiviral properties uye sezvingangoita inhibitors yehutachiona hwehutachiona. Pamusoro pezvo, sialidase inhibitors, iyo inodzivirira kubviswa kweasilic acid masara kubva kumaglycans, iri kuongororwa nekuda kwekushandisa kwavo kurapa.
- Glycobiology Research: Sialic acid uye sialylated glycans inodzidzwa zvakanyanya mumunda weglycobiology. Ongororo yavo inogona kupa ruzivo rwemaitiro echirwere, mashandiro emasero, uye kuwanikwa kwebiomarker.
- Diagnostic Tools: Sialic acid mazinga, shanduko, uye gadziridzo dzinoshandiswa sebiomarkers muzvirwere zvakasiyana sekenza, chirwere chemoyo, uye genetic kusagadzikana. Kuona uye kuongororwa kweasilic acid kunogona kupa ruzivo rwakakosha rwekuongorora.
- Indasitiri yeChikafu neKunovaka muviri: Sialic acid inowanikwa mune zvimwe zvekudya, semukaka nemazai. Dzimwe nguva inowedzerwa kumishonga yevacheche sekuwedzera kwekudya kune vacheche vasina kuyamwisa.
Kunyorwa kwechinyorwa:Coco Zhang
Nguva yekutumira: Jan-12-2024
