Aogubio ke k'hamphani e ikhethileng tlhahisong le kabong ea lintho tse sebetsang ka mokhoa oa pharmacologically, lisebelisoa tse tala, li-extracts tsa limela le limatlafatsi bakeng sa tlhahiso ea li-supplement tsa batho. Lihlahisoa tsa rona li sebelisoa indastering ea meriana le ea meriana, ea lijo, ea phepo e nepahetseng le ea litlolo. E 'ngoe ea lihlahisoa tsa rona tse tsebahalang haholo keCDP-Choline , e tsejoang hape e le CITICOLINE. CDP-Choline ke motsoako oa nootropic o sebetsang e le prodrug bakeng sa choline le uridine, ho fana ka 'mele ka limolek'hule tsena tsa bohlokoa ha li nkoa ka molomo.
CDP-Choline ke eng?
Citicoline, e tsejoang hape e le CDP-choline kapa cytidine diphosphate-choline, e khetholloa e le ntho ea nootropic ka lebaka la liphello tsa eona tse matlafatsang tsebo.
Ke selelekela sa choline le cytidine.
Choline le cytidine ka bobeli lia hlokahala bakeng sa ho kopanya likarolo tsa bohlokoa tsa lisele, haholo bokong.
Melemo e 10 e netefalitsoeng ea Citicoline (CDP-Choline)
Liphuputso tse ngata li bontšitse hore CDP-choline e sebetsa ho feta phosphatidylcholine (PC) ho thibela ho senyeha ha mohopolo. Ho phaella moo, ho bontšitsoe ho eketsa motsoako oa PC bokong, kahoo e tlatsetsa liphellong tsa eona tsa neuroprotective. Leha CDP-Choline e bapisoa ka katleho le Alpha-GPC, e fana ka melemo e felletseng bakeng sa ts'ebetso ea kelello.
- Citicoline e ntlafatsa mohopolo
Citicoline e bontšitsoe ho ntlafatsa mohopolo.
Sena se bakoa ke karolo ea eona ea ho eketsa maemo a acetylcholine, neurotransmitter ea bohlokoa bakeng sa mohopolo le ho ithuta.
Liphuputso tse ngata li bontšitse liphello tse matlafatsang mohopolo tsa Citicoline.
Phuputsong e 'ngoe, batho ba baholo ba nang le bothata ba ho hopola lintho tse amanang le lilemo ba ile ba nka Citicoline libeke tse 12.
Batsayakarolo ba thutopatlisiso ba ne ba amogela 1,000 mg kgotsa 500 mg ya Citicoline letsatsi le letsatsi.
Ba bile le ntlafatso ea mohopolo ka mor'a ho e nka.
Bafuputsi le bona ba hlahlobile litlamorao tsa Citicoline ho basali ba baholo ba phetseng hantle.
Basali ba ile ba nka 250 mg kapa 500 mg ea letsatsi le letsatsi ea Citicoline ka matsatsi a 28.
E lebisitse ntlafatsong e khōlō ea tšebetso ea kelello, ho akarelletsa le mohopolo .
Qetellong, sehlopha sa bafuputsi se ile sa hlahloba lithuto tse fapa-fapaneng ka liphello tsa Citicoline mabapi le ho hlaphoheloa ke stroke.
Ba fihletse qeto ea hore bakuli ba amohetseng Citicoline ba bontšitse ntlafatso ea mohopolo le ts'ebetso ea kelello.
Lithuto tsena, har'a tse ling, li fana ka bopaki bo matla bakeng sa liphello tse matlafatsang mohopolo tsa Citicoline.
- Citicoline e Ntlafatsa Tsepamiso le Tlhokomelo
Citicoline e ts'ehetsa motsoako oa li-neurotransmitters tsa bohlokoa, joalo ka acetylcholine le dopamine, tse bapalang likarolo tsa bohlokoa tlhokomelong le ho tsepamisa maikutlo.
Ka ho eketsa boteng ba li-neurotransmitters tsena, Citicoline e thusa ho ntlafatsa tlhokomelo le ho tsepamisa maikutlo.
Lipatlisiso li fumane hore sena ke ’nete.
Liphuputso tse 'maloa li bontšitse hore tlatsetso ea Citicoline e ka thusa ho ntlafatsa tlhokomelo, ho tsepamisa maikutlo le ho tsepamisa mohopolo.
Phuputsong e 'ngoe, basali ba baholo ba phetseng hantle ba ile ba nka 250-500 mg letsatsi le leng le le leng la Citicoline ka matsatsi a 28.
Bafuputsi ba fumane hore basali ba bile le ntlafatso e kholo ts'ebetsong ea tlhokomelo.
Phuputsong e 'ngoe, bafuputsi ba fumane hore batho ba baholo ba phetseng hantle ba nkileng Citicoline libeke tse tšeletseng ba bile le ntlafatso ea tlhokomelo le ts'ebetso ea kelello.
'Me joale thuto e laoloang ka mokhoa o sa reroang, e sa boneng habeli, e laoloang ke placebo e shebile liphello tsa Citicoline mabapi le ts'ebetso ea kelello ho baithaopi ba banna ba phetseng hantle.
Bafuputsi ba fumane hore barupeluoa ba amohetseng Citicoline ba bontšitse ntlafatso e kholo tlhokomelong, mohopolong oa ho sebetsa, le ho tenyetseha ha kelello.
Ha ho nahanoa ka lipatlisiso tsena kaofela, ho hlakile hore Citicoline e ka ba molemo haholo ho baithuti, litsebi, kapa mang kapa mang ea batlang ho ntlafatsa tsepamiso ea bona le ts'ebetso ea bona ea kelello ka kakaretso.
- Citicoline ke Neuroprotective
Citicoline e tsejoa e le neuroprotective.
E sireletsa lisele tsa boko ho senyeha le ho senyeha.
E etsa sena ka ho boloka botšepehi ba lisele tsa lisele, ho fokotsa khatello ea oxidative, le ho fokotsa ho ruruha bokong.
Liphello tsena li kenya letsoho ho bophelo bo botle ba boko. Li ka boela tsa sireletsa khahlanong le ho fokotseha ha kelello le maemo a neurodegenerative.
Liphuputso tse 'maloa li bontšitse liphello tsa neuroprotective tsa Citicoline, haholo-holo maemong a ischemic stroke, kotsi e bohloko ea boko, le ho fokotseha ha kelello.
Bafuputsi ba fumane hore Citicoline e ka thusa ho laola maemo a glutamate, neurotransmitter e thabisang. Glutamate e ka baka tšenyo ea methapo ha e le teng ka bongata bo feteletseng.
- Citicoline e thusa ka ho hlaphoheloa ha stroke
Liphuputso li bontšitse hore Citicoline e ka thusa ts'ebetsong ea ho hlaphoheloa ka mor'a ho otloa ke stroke.
E etsa sena ka ho ntlafatsa polasetiki ea boko, ho khothaletsa kholo ea likhokahano tse ncha tsa methapo ea kutlo, le ho fokotsa ho ruruha le tšenyo ea methapo.
Ka lebaka leo, hangata e sebelisoa e le pheko ea tlatsetso hammoho le liphekolo tse tloaelehileng tsa stroke.
Citicoline e bonahala e thusa haholo-holo ho bakuli ba tšoeroeng ke lefu la ischemic.
Ischemic stroke e etsahala ha phallo ea mali e eang bokong e koetsoe, e lebisang khaellong ea oksijene le limatlafatsi. Sena se ka baka lefu la lisele le tšenyo ea methapo.
Tlhahlobo e kopaneng ea liteko tsa tleliniki e ile ea sheba litlamorao tsa Citicoline ka lefu la ischemic stroke.
Bafuputsi ba fumane hore bakuli ba amohetseng Citicoline ba bile le liphello tse ntlafetseng tsa ts'ebetso le tsebo ea kelello.
Tlhahlobo e 'ngoe ea lipatlisiso e hlahlobile karolo ea Citicoline ho neuroprotection le neurorepair ho ischemic stroke.
Bangoli ba ile ba etsa qeto ea hore Citicoline e ne e mamelloa hantle ka kakaretso 'me e ka ntlafatsa liphello tse sebetsang le tsa kelello ho bakuli ba stroke. Sena e ne e le 'nete haholo ha e ne e sebelisoa qalong ea phekolo .
- Citicoline e Ntlafatsa Boikutlo le Tšusumetso
Citicoline e 'nile ea amahanngoa le maemo a eketsehileng a dopamine, neurotransmitter e amanang le tšusumetso, thabo le moputso.
Phello ena e ka thusa ho ntlafatsa maikutlo, tšusumetso, le bophelo bo botle ka kakaretso.
Ka lebaka leo, liphuputso tse ling li khothalelitse hore Citicoline e na le litlamorao tse kang antidepressant.
Phuputsong e 'ngoe, bafuputsi ba ile ba batlisisa liphello tsa Citicoline supplementation ka maikutlo le matla a kelello.
Teko e kenyelelitse bankakarolo ba baholo ba 60 ba phetseng hantle. Ba fumane Citicoline (250 mg / letsatsi kapa 500 mg / letsatsi) kapa placebo bakeng sa libeke tse tšeletseng.
Barupeluoa ba amohetseng Citicoline ba tlalehile ntlafatso ea maikutlo le matla a bona a kelello .
- Citicoline e Ntlafatsa ho Ithuta
Citicoline e bontšitsoe ho ntlafatsa ho ithuta.
E etsa sena ka ho khothaletsa likarolo tse fapaneng tsa ts'ebetso ea kelello, ho kenyelletsa mohopolo, tlhokomelo, le neuroplasticity.
Phuputsong e 'ngoe, bafuputsi ba ile ba batlisisa liphello tsa Citicoline ho ithuta le ho hopola batho ba baholo.
Teko ena e ne e kenyelletsa batho ba baholo ba 60 ba phetseng hantle. Ba fumane Citicoline (250 mg / letsatsi kapa 500 mg / letsatsi) kapa placebo ka matsatsi a 28.
Bafuputsi ba fumane hore barupeluoa ba amohetseng Citicoline ba bonts'itse ts'ebetso e ntlafetseng mesebetsing e fapaneng ea kelello, ho kenyeletsa le e amanang le ho ithuta.
- Citicoline E Eketsa Acetylcholine Bokong
Acetylcholine ke neurotransmitter ea bohlokoa e amehang likarolong tse fapaneng tsa ts'ebetso ea kelello, ho kenyelletsa ho ithuta, mohopolo le tlhokomelo.
Ha Citicoline e kenngoa 'me e etsoa ka metabolized, e robehile ka choline.
Joale choline e ka tšela mokoallo oa mali-boko 'me ea kena bokong.
Hang ha e le bokong, choline e sebelisoa ho kopanya acetylcholine.
Ka lebaka leo, Citicoline e bontšitsoe ho eketsa maemo a choline le acetylcholine bokong. Joale sena se kenya letsoho ntlafatsong ea ts'ebetso ea kelello.
Liphuputso tse 'maloa li bontšitse hore tlatsetso ea Citicoline e ka lebisa ho eketseha ha maemo a acetylcholine bokong.
Phuputsong e 'ngoe, bafuputsi ba ile ba batlisisa liphello tsa Citicoline ho cholinergic neurotransmission.
Liphetho li bontšitse hore Citicoline e ekelitse ho lokolloa ha acetylcholine hippocampus, e leng sebaka sa boko se bohlokoa bakeng sa ho ithuta le ho hopola.
Boithuto bo bong bo ile ba sheba litlamorao tsa Citicoline polelong ea matšoao a polasetiki ea boko.
Bangoli ba fumane hore Citicoline e lebisitse ho eketseha ha maemo a acetylcholine bokong.
Ena ke lithuto tse peli feela ho tse ngata tse bontšang hore Citicoline supplementation e ka eketsa maemo a acetylcholine bokong.
- Citicoline E Fokotsa Ho ruruha Bokong
Ho ruruha ho phetha karolo ea bohlokoa ho nts'etsopele le tsoelo-pele ea mafu a fapaneng a methapo ea kutlo. Sena se kenyelletsa lefu la Alzheimer, lefu la Parkinson le stroke.
Empa Citicoline e bonts'itsoe e na le thepa e thibelang ho ruruha, 'me e ka thusa ho fokotsa ho ruruha bokong.
Ka mohlala, Citicoline e fokotsa haholo tlhahiso ea li-cytokine tse thibelang ho ruruha bokong .
Phuputsong e 'ngoe, bafuputsi ba ile ba hlahloba liphello tsa Citicoline ka khatello ea oxidative le ho ruruha ka mokhoa oa mouse oa lefu la Alzheimer.
Bangoli ba fumane hore Citicoline e fokolitse khatello ea oxidative le ho ruruha bokong. Phokotso ena ea ho ruruha e ile ea amahanngoa le ts'ebetso e ntlafetseng ea kelello ho litoeba.
Ka ho fokotsa ho ruruha ha boko, Citicoline e ka thusa ho boloka bophelo bo botle ba boko, le ho thusa ho thibela nts'etsopele ea mafu a neurodegenerative.
- Citicoline e Ntlafatsa Boko ba Plasticity
Boko ba polasetiki ke bokhoni ba boko ba ho fetoha le ho ikamahanya le maemo ho latela liphihlelo tse ncha.
Polasetiki ea boko e bapala karolo ea bohlokoa ho thehoeng ha likhokahano tse ncha lipakeng tsa methapo ea kutlo (synaptogenesis) le kholo ea methapo e mecha (neurogenesis).
Ka bobeli synaptogenesis le neurogenesis li bohlokoa bakeng sa ho ithuta, ho hopola le ho hlaphoheloa likotsing tsa boko.
Citicoline e bontšitsoe ho ntlafatsa polasetiki ea boko, synaptogenesis le neurogenesis.
Phuputsong e 'ngoe, bafuputsi ba ile ba batlisisa litlamorao tsa Citicoline polelong ea matšoao a polasetiki ea boko ka mohlala oa rat ea stroke.
Liphello li bontšitse hore Citicoline e entse hore ho be le polelo e eketsehileng ea liprotheine tse amanang le polasetiki le lintlha tsa ho hōla, tse kang BDNF le NGF.
Phuputso e 'ngoe e fumane hore Citicoline e ntlafatsa polasetiki ea boko 'me e khothalletsa ho hlaphoheloa ka mor'a stroke.
- Citicoline e thusa ka ho fokotseha ha kelello, ho se sebetse hantle ha kelello, le lefu la Alzheimer's.
Ho fokotseha ha kelello ho khetholloa ke ho fokotseha butle-butle mesebetsing ea kelello, ho kopanyelletsa le mohopolo, tlhokomelo, le bokhoni ba ho rarolla mathata.
Citicoline e bonts'itsoe hore e liehisa ho fokotseha ha kelello, haholo ho batho ba tsofetseng le ba nang le mafu a neurodegenerative joalo ka lefu la Alzheimer's.
Liphuputso tse 'maloa li bontšitse melemo ea Citicoline ho fokotsa ho fokotseha ha kelello.
Phuputso e 'ngoe e ile ea sheba liphello tsa nako e telele tsa Citicoline ho bakuli ba hōlileng ba nang le bokooa bo fokolang ba kelello.
Bafuputsi ba fumane hore likhoeli tsa 9 tsa tlatsetso ea Citicoline li ntlafalitse haholo ts'ebetso ea kelello ho bakuli bana.
Phuputso e 'ngoe e ile ea batlisisa liphello tsa Citicoline mabapi le ho fokotseha ha kelello ho bakuli ba nang le lefu la Alzheimer's.
Teko e fumane hore bakuli ba amohetseng Citicoline ka likhoeli tse 12 ba ile ba fokotseha butle butle mosebetsing oa kelello.
'Me joale tlhahlobo e hlophisitsoeng e ile ea hlahloba katleho ea Citicoline ho phekola tšitiso ea kelello le ea boitšoaro ho bakuli ba tsofetseng.
Bangoli ba ile ba etsa qeto ea hore Citicoline e bontšitse melemo e meng ea ho ntlafatsa matšoao a kelello le a boitšoaro ho bakuli bana.
Bokhoni ba Citicoline ba ho fokotsa ho fokotseha ha kelello bo ka bakoa ke mekhoa e mengata. E ka ntlafatsa tlhahiso ea li-neurotransmitter, ea ts'ehetsa botšepehi ba membrane ea boko, ea eketsa polasetiki ea boko, 'me ea fokotsa ho ruruha.
Ea ronaCDP Choline li-supplement li fumaneha ka mefuta e sa tšoaneng, ho kenyelletsa le li-capsules le phofo, ho lumella bareki ba rona ho khetha khetho e loketseng ka ho fetisisa bakeng sa litlhoko tsa bona. Hore na o moreki ea batlang tlatsetso e tšepahalang ea ts'ehetso ea kelello, kapa khoebo ea indasteri ea meriana kapa ea phepo e batlang lisebelisoa tsa boleng bo holimo, CDP-Choline ea Aogubio ke khetho e phethahetseng.
Ke lijo life tseo nka fumanang choline ho tsona?
Mohlomong u se u ntse u ja lijo tse ngata tse nang le choline. Choline e ka fumanoa mefuteng ea lijo tse kenyeletsang:
- Litapole.
- Linaoa, linate le peo.
- Lithollo tse felletseng.
- Nama, likhoho le tlhapi.
- Lebese le mahe.
- Meroho e kang broccoli le cauliflower.
Ka kakaretso, CITICOLINE ea Aogubio ke tlatsetso e matla le e sebetsang ho ts'ehetsa bophelo bo botle ba kelello le ts'ebetso. Ka motsoako oa eona o ikhethang oa choline le uridine, e fana ka melemo e felletseng bakeng sa mohopolo, ho ithuta le bophelo bo botle ba boko ka kakaretso. Hore na o batla ho ntlafatsa ts'ebetso ea hau ea kelello kapa o batla lisebelisoa tsa boleng bo holimo bakeng sa lihlahisoa tsa hau, AoguBio'sCDP-Choline ke tharollo e phethahetseng bakeng sa hau. Eba le matla a CITICOLINE 'me u nke bophelo ba hau ba kelello boemong bo latelang ka Aogubio.
Ho ngola sengoloa: Miranda Zhnag
Nako ea poso: Jan-17-2024
