Izinzuzo ezingaziwa ze-CDP-Choline:

Izinzuzo Ezifakazelwe eziyi-10 ze-Citicoline (I-CDP-Choline)

Ucwaningo oluningi luye lwabonisa ukuthi i-CDP-choline iphumelela kakhulu kune-phosphatidylcholine (PC) ekuvimbeleni ukukhubazeka kwememori. Ukwengeza, kuye kwaboniswa ukwandisa ukuhlanganiswa kwe-PC ebuchosheni, ngaleyo ndlela kube nomthelela emiphumeleni yayo ye-neuroprotective. Nakuba i-CDP-Choline iqhathaniswa ngokusebenza ngempumelelo ne-Alpha-GPC, inikeza izinzuzo ezibanzi kakhulu zomsebenzi wokuqonda.

• I-Citicoline Ithuthukisa Inkumbulo

I-Citicoline iboniswe ukuthuthukisa inkumbulo.

Lokhu kubangelwa ingxenye yayo ekwandiseni amazinga e-acetylcholine, i-neurotransmitter ebalulekile ekukhumbuleni nokufunda.

Ucwaningo oluningi luye lwabonisa imiphumela yokuthuthukisa inkumbulo ye-Citicoline.

Kokunye ukuhlola, abantu abadala asebekhulile abanokukhubazeka kwenkumbulo okuhlobene neminyaka bathatha i-Citicoline amasonto angu-12.

Ababambiqhaza bocwaningo bathole u-1,000 mg noma u-500 mg we-Citicoline nsuku zonke.

Babona ukuthuthuka kwenkumbulo ngemuva kokuyithatha.

Abacwaningi baphinde bahlola imiphumela ye-Citicoline kwabesifazane abadala abanempilo.

Abesifazane bathatha 250 mg noma 500 mg imithamo nsuku zonke ye-Citicoline izinsuku ezingu-28.

Kuholele ekuthuthukisweni okuphawulekayo ekusebenzeni kwengqondo, okuhlanganisa inkumbulo .

Okokugcina, ithimba labacwaningi lihlaziye izifundo ezihlukahlukene ngemiphumela ye-Citicoline ekubuyiseleni isifo sohlangothi.

Baphetha ngokuthi iziguli ezathola i-Citicoline zibonise ukuthuthukiswa kwenkumbulo nokusebenza kwengqondo.

Lezi zifundo, phakathi kokunye, zinikeza ubufakazi obuqinile bemiphumela yokuthuthukisa inkumbulo ye-Citicoline.

• I-Citicoline Ithuthukisa Ukugxila Nokunaka

I-Citicoline isekela ukuhlanganiswa kwama-neurotransmitters abalulekile, njenge-acetylcholine ne-dopamine, adlala indima ebalulekile ekunakeni nasekugxilweni.

Ngokwandisa ukutholakala kwalawa ma-neurotransmitters, i-Citicoline isiza ukuthuthukisa ukunaka nokugxila.

Ucwaningo luthole ukuthi lokhu kuyiqiniso.

Ucwaningo oluningana lubonise ukuthi i-Citicoline supplementation ingasiza ekuthuthukiseni ukunaka, ukugxila, nokugxila.

Kolunye ucwaningo, abesifazane abadala abanempilo bathatha 250-500 mg imithamo yansuku zonke ye-Citicoline izinsuku ezingama-28.

Abacwaningi bathola ukuthi abesifazane bathole ukuthuthuka okukhulu ekusebenzeni kokunaka .

Kolunye ucwaningo, abacwaningi bathola ukuthi abantu abadala abaphile kahle abathathe i-Citicoline amasonto ayisithupha bathole ukuthuthuka ekunakeni nasekusebenzeni kwengqondo .

Bese kuthi ucwaningo olungahleliwe, olungaboni kabili, olulawulwa yi-placebo lubheke imiphumela ye-Citicoline ekusebenzeni kwengqondo kumavolontiya wesilisa anempilo.

Abacwaningi bathola ukuthi ababambiqhaza abathole i-Citicoline babonise ukuthuthukiswa okuphawulekayo ekunakeni, inkumbulo yokusebenza, nokuguquguquka kwengqondo.

Uma kucatshangelwa lonke lolu cwaningo, kucace kakhulu ukuthi i-Citicoline ingaba yinzuzo ikakhulukazi kubafundi, ochwepheshe, nanoma ubani ofuna ukuthuthukisa ukugxila kwabo kanye nokusebenza kwengqondo kukonke.

• I-Citicoline iyi-Neuroprotective

I-Citicoline yaziwa njenge-neuroprotective.

Ivikela amangqamuzana obuchopho ekulimaleni nasekuwohlokeni.

Lokhu ikwenza ngokugcina ubuqotho bolwelwesi lwamangqamuzana, ukwehlisa ukucindezeleka kwe-oxidative, nokunciphisa ukuvuvukala ebuchosheni.

Le miphumela inomthelela empilweni yobuchopho jikelele. Bangakwazi futhi ukuvikela ekunciphiseni kwengqondo kanye nezimo ze-neurodeergenerative.

Ucwaningo oluningana lubonise imiphumela ye-neuroprotective ye-Citicoline, ikakhulukazi ezimeni ze-ischemic stroke, ukulimala kobuchopho okubuhlungu, nokuncipha kwengqondo.

Abacwaningi bathola ukuthi i-Citicoline ingasiza ekulawuleni amazinga e-glutamate, i-neurotransmitter ejabulisayo. I-Glutamate ingabangela ukulimala kwe-neuronal uma ikhona ngamanani eqile .

• I-Citicoline Isiza Ngokululama Kwesifo Sohlangothi

Ucwaningo luye lwabonisa ukuthi i-Citicoline ingasiza enqubweni yokutakula ngemva kokushaywa yisifo sohlangothi.

Lokhu ikwenza ngokuthuthukisa ipulasitiki yobuchopho, ikhuthaze ukukhula kokuxhumana okusha kwemizwa, nokunciphisa ukuvuvukala nokulimala kwe-neuronal.

Ngenxa yalokho, ngokuvamile isetshenziswa njengokwelashwa okuhambisanayo kanye nokwelashwa okujwayelekile kokushaywa unhlangothi.

I-Citicoline ibonakala iwusizo ikakhulukazi ezigulini eziye zahlushwa yi-ischemic stroke.

I-Ischemic stroke yenzeka lapho ukugeleza kwegazi ukuya ebuchosheni kuvinjiwe, okuholela ekuntulekeni komoyampilo kanye nezakhamzimba. Lokhu kungabangela ukufa kwamangqamuzana nokulimala kwemizwa.

Ukuhlaziywa okuhlanganisiwe kokuhlolwa komtholampilo kubheke imiphumela ye-Citicoline ku-acute ischemic stroke.

Abacwaningi bathola ukuthi iziguli ezithole i-Citicoline zithole imiphumela ethuthukisiwe yokusebenza neyokuqonda .

Okunye ukubuyekezwa kocwaningo kuhlole indima ye-Citicoline ku-neuroprotection kanye ne-neurorepair ku-stroke ye-ischemic.

Abalobi baphetha ngokuthi i-Citicoline yayivame ukubekezelelwa kahle futhi ingathuthukisa imiphumela esebenzayo neyokuqonda ezigulini ze-stroke. Lokhu bekuyiqiniso ikakhulukazi lapho kunikezwa ekuqaleni kwenqubo yokwelapha .

• I-Citicoline Ithuthukisa Isimo Senhliziyo Nogqozi

I-Citicoline iye yaxhunyaniswa namazinga anda e-dopamine, i-neurotransmitter ehlotshaniswa nogqozi, injabulo, nomvuzo.

Lo mphumela ungasiza ukuthuthukisa isimo sengqondo, ugqozi, kanye nokuphila kahle.

Ngenxa yalokho, ezinye izifundo ziye zaphakamisa ukuthi i-Citicoline inemiphumela efana ne-antidepressant.

Kwesinye isifundo, abacwaningi baphenye imiphumela ye-Citicoline supplementation kuma-mood namandla engqondo.

Uhlolo lwalubandakanya ababambiqhaza abadala abanempilo engama-60. Bathola i-Citicoline (250 mg/day noma 500 mg/day) noma i-placebo amasonto ayisithupha.

Abahlanganyeli abathole i-Citicoline babike ukuthuthuka kwemizwa yabo namandla engqondo .

• I-Citicoline Ithuthukisa Ukufunda

I-Citicoline ikhonjiswe ukuthuthukisa ukufunda.

Lokhu ikwenza ngokukhuthaza izici ezihlukahlukene zokusebenza kwengqondo, okuhlanganisa inkumbulo, ukunaka, kanye ne-neuroplasticity.

Kwesinye isifundo, abacwaningi baphenye imiphumela ye-Citicoline ekufundeni nasekukhumbuleni kubantu abadala.

Lolu cwaningo lwaluhlanganisa abantu abadala abanempilo enempilo engama-60. Bathola i-Citicoline (250 mg/day noma 500 mg/day) noma i-placebo izinsuku ezingama-28.

Abacwaningi bathola ukuthi ababambiqhaza abathole i-Citicoline babonise ukusebenza okuthuthukisiwe emisebenzini ehlukahlukene yengqondo, kuhlanganise naleyo ehlobene nokufunda.

• I-Citicoline Yandisa I-Acetylcholine ebuchosheni

I-Acetylcholine iyi-neurotransmitter ebalulekile ehilelekile ezicini ezihlukahlukene zokusebenza kwengqondo, okuhlanganisa ukufunda, inkumbulo, nokunaka.

Lapho i-Citicoline idliwe futhi ifakwe i-metabolized, ihlehliswa ibe yi-choline.

I-choline ingabe isiwela umgoqo wegazi nobuchopho futhi ingene ebuchosheni.

Uma isisebuchosheni, i-choline isetshenziselwa ukuhlanganisa i-acetylcholine.

Ngenxa yalokho, i-Citicoline iboniswe ukwandisa amazinga e-choline ne-acetylcholine ebuchosheni. Lokhu bese kuba nomthelela ekusebenzeni okuthuthukisiwe kwengqondo.

Ucwaningo oluningana luye lwabonisa ukuthi ukwesekwa kwe-Citicoline kungaholela ekwandeni kwamazinga e-acetylcholine ebuchosheni.

Kwesinye isifundo, abacwaningi baphenye imiphumela ye-Citicoline ku-cholinergic neurotransmission.

Imiphumela yabonisa ukuthi i-Citicoline yandisa ukukhululwa kwe-acetylcholine ku-hippocampus, okuyindawo yobuchopho ebalulekile ekufundeni nasekukhumbuleni.

Olunye ucwaningo lubheke imiphumela ye-Citicoline ekuvezeni izimpawu ze-plasticity yobuchopho.

Ababhali bathola ukuthi iCiticoline iholele ekwandeni kwamazinga e-acetylcholine ebuchosheni.

Lokhu kuyizifundo ezimbili nje kweziningi ezibonisa ukuthi i-Citicoline supplementation ingakhuphula amazinga e-acetylcholine ebuchosheni.

• I-Citicoline Yehlisa Ukuvuvukala Engqondweni

Ukuvuvukala kudlala indima ebalulekile ekuthuthukiseni nasekuqhubekeleni phambili kwezifo ezihlukahlukene zezinzwa. Lokhu kuhlanganisa isifo i-Alzheimer's, isifo sikaParkinson, nesifo sohlangothi.

Kodwa i-Citicoline ikhonjiswe ukuthi inezindawo zokulwa nokuvuvukala, futhi ingasiza ekwehliseni ukuvuvukala ebuchosheni.

Ngokwesibonelo, i-Citicoline inciphisa kakhulu ukukhiqizwa kwama-cytokine abangela ukuvuvukala ebuchosheni .

Kolunye ucwaningo, abacwaningi bahlola imiphumela ye-Citicoline ekucindezelekeni kwe-oxidative nokuvuvukala kumodeli yegundane yesifo i-Alzheimer's.

Ababhali bathola ukuthi i-Citicoline yehlisa ukucindezeleka kwe-oxidative nokuvuvukala ebuchosheni. Lokhu kuncipha kokuvuvukala kwabe sekuhlotshaniswa nokusebenza okuthuthukisiwe kwengqondo kumagundane.

Ngokunciphisa ukuvuvukala kobuchopho, i-Citicoline ingasiza ekugcineni impilo yobuchopho, futhi isize ukuvimbela ukuthuthukiswa kwezifo ze-neurodeergenerative.

• I-Citicoline Ithuthukisa I-Brain Plasticity

Ipulasitiki yobuchopho yikhono lobuchopho lokushintsha nokuzivumelanisa nezimo ekuphenduleni okuhlangenwe nakho okusha.

Ipulasitiki yobuchopho idlala indima ebalulekile ekwakhekeni kokuxhumana okusha phakathi kwama-neurons (synaptogenesis) kanye nokukhula kwama-neuron amasha (neurogenesis).

Kokubili i-synaptogenesis ne-neurogenesis ibalulekile ekufundeni, ekukhumbuleni, nasekululameni ekulimaleni kobuchopho.

I-Citicoline ikhonjiswe ukuthuthukisa ipulasitiki yobuchopho, i-synaptogenesis kanye ne-neurogenesis.

Kolunye ucwaningo, abacwaningi baphenye imiphumela ye-Citicoline ekuboniseni izimpawu ze-plasticity yobuchopho kumodeli yegundane ye-stroke.

Imiphumela yabonisa ukuthi i-Citicoline iholele ekwandiseni ukubonakaliswa kwamaprotheni ahlobene ne-plasticity kanye nezici zokukhula, njenge-BDNF ne-NGF.

Olunye ucwaningo lwathola ukuthi i-Citicoline ithuthukisa i-plasticity yobuchopho futhi ikhuthaze ukululama ngemva kokushaywa unhlangothi.

• I-Citicoline Isiza Ngokuncipha Kwengqondo, Ukukhubazeka Kwengqondo Okumaphakathi, kanye Nesifo I-Alzheimer's

Ukuncipha kwengqondo kubonakala ngokuncipha kancane kancane kwemisebenzi yengqondo, okuhlanganisa inkumbulo, ukunaka, namakhono okuxazulula izinkinga.

I-Citicoline ikhonjiswe ukuthi yehlisa ijubane ukwehla kwengqondo, ikakhulukazi kubantu asebekhulile nalabo abahlushwa izifo ze-neurodeergenerative ezifana nesifo i-Alzheimer's.

Ucwaningo oluningana lubonise izinzuzo ze-Citicoline ekwehliseni ijubane lokuncipha kwengqondo.

Ucwaningo olulodwa lwabheka imiphumela yesikhathi eside ye-Citicoline ezigulini esezikhulile ezinokukhubazeka okuncane kwengqondo.

Abacwaningi bathola ukuthi izinyanga ezingu-9 ze-Citicoline supplementation zithuthukise kakhulu ukusebenza kwengqondo kulezi ziguli.

Olunye ucwaningo lwaphenya imiphumela ye-Citicoline ekunciphiseni kwengqondo ezigulini ezinesifo i-Alzheimer's.

Uhlolo lwathola ukuthi iziguli ezithole i-Citicoline izinyanga ezingu-12 zibe nokwehla kancane komsebenzi wokuqonda .

Futhi-ke ukubuyekezwa okuhlelekile kwahlola ukusebenza kahle kwe-Citicoline ekwelapheni ukuphazamiseka kwengqondo nokuziphatha ezigulini esezikhulile.

Ababhali baphethe ngokuthi i-Citicoline ibonise izinzuzo ezithile ekuthuthukiseni izimpawu zokuqonda nokuziphatha kulezi ziguli.

Ikhono le-Citicoline lokwehlisa ijubane lokuncipha kwengqondo lingabangelwa izindlela ezimbalwa. Ingathuthukisa ukukhiqizwa kwe-neurotransmitter, isekele ubuqotho be-membrane yamangqamuzana obuchopho, ikhulise ipulasitiki yobuchopho, futhi yehlise ukuvuvukala.