Chitosan ni iki, kandi ikora ite?
Urashaka inzira karemano yo gushyigikira kugabanuka no kugabanya cholesterol? Chitosan nigisubizo cyawe.Chitosan , ikomoka kuri chitine (ifumbire ya fibrous iboneka cyane cyane muri exoskeletons ikomeye ya crustaceans no mu rukuta rw'utugingo ngengabuzima tumwe na tumwe), ni inyongera ikomeye ishobora gufasha kugera kuri izo ntego z'ubuzima. Muri AOGU Bio, tuzobereye mu gukora no gukwirakwiza ibintu bikoreshwa mu bya farumasi n’ibikoresho fatizo, harimo na chitosani, kugira ngo bikoreshwe mu nyongeramusaruro z’abantu, ku bicuruzwa bya farumasi, no mu bya farumasi, ibiryo, intungamubiri n’amavuta yo kwisiga.
Chitosan ikorwa binyuze mumikorere ya enzymatique ikora ifishi ikwiranye ninyongera. Ibi bivuze ko byoroshye kwinjizwa numubiri, bigatuma bigira akamaro mukuzamura ibiro no kugabanya urugero rwa cholesterol. Kwibanda kwa Aogubio kumasoko karemano kandi arambye yemeza ko chitosan yacu ifite ubuziranenge kandi ntarimo inyongeramusaruro cyangwa imiti yangiza.
Inyungu zaChitosanInyongera
Binyuze mu bushakashatsi bwa siyansi, chitosan yasanze ifite mikorobe, antioxydants, anti-inflammatory, nibindi bintu. Iyi miterere yibinyabuzima irashobora kuba ingirakamaro mubuzima butandukanye.
Ubushakashatsi bukomeje kwigaragaza mugihe abashakashatsi biga byinshi kuri polysaccharide nibishobora gukoreshwa. Bimwe mubishoboka gukoresha chitosan byerekanwe hano hepfo.
- Gicurasi Kugabanya Isukari Yamaraso Yinshi
Chitosan yasabwe nk'ubuvuzi bwuzuzanya bw'isukari nyinshi mu maraso, ikimenyetso rusange cya syndrome de metabolike (itsinda ry'imiterere ishobora gutera indwara z'umutima, diyabete, na stroke) na diyabete yo mu bwoko bwa 2.
Ubushakashatsi bw’inyamaswa na laboratoire bwerekanye isano iri hagati ya chitosani no kunoza isukari mu maraso binyuze mu kugabanuka kwa insuline (iyo imitsi, umwijima, hamwe n’ibinure bititabira neza insuline kandi ntibishobora gufata glucose mu maraso, bigatuma hakenerwa pancreas to kora insuline nyinshi) no kongera isukari mu maraso gufata tissue. Izi nyungu zageragejwe mubigeragezo bitandukanye byamavuriro.
Isesengura ryakozwe na test 10 yubuvuzi ryagaragaje ibisubizo bivuguruzanya bijyanye ningaruka za chitosani mukugabanya isukari yamaraso. Mugihe chitosan yasaga nkigabanya isukari yamaraso yisonzesha hamwe na hemoglobine A1c (HbA1c), ikizamini cyamaraso kugirango isuzume igipimo cyisukari cyamaraso mugihe cyamezi atatu, ntabwo cyagize ingaruka zikomeye kurwego rwa insuline.
Abashakashatsi bagaragaje ko ibisubizo byiza byagaragaye igihe chitosani yakoreshwaga ku kigero cya garama 1,6 kugeza kuri 3 (g) ku munsi kandi byibura ibyumweru 13.
Ubushakashatsi bumwe bwerekanye ko chitosan ishobora no kugira uruhare mu kwirinda diyabete. Mu bushakashatsi, abitabiriye diyabete ya prediabete (iyo glucose yamaraso iri hejuru ariko itari hejuru bihagije ku buryo byafatwa nka diyabete) bahisemo gufata ikibanza (ikintu kidafite inyungu) cyangwa inyongera ya chitosani mu byumweru 12. Ugereranije na placebo, chitosan yazamuye umuriro, HbA1c, hamwe nisukari yamaraso.
Muri rusange, ibigeragezo byabantu kuri chitosan yo kugenzura isukari yamaraso ntibibura mubunini bwubushakashatsi. Ubushakashatsi bwiyongereye burakenewe muriki gice.
- Ashobora kugabanya umuvuduko ukabije wamaraso
Umubare muto wibigereranyo byamavuriro byagaragaje isano iri hagati ya chitosan numuvuduko wamaraso. By'umwihariko, chitosan yabonetse igabanya umuvuduko ukabije wamaraso mubushakashatsi buke bwabantu. Nyamara, ibisubizo bimwe byubushakashatsi byavanze.
Chitosan yatekereje kugabanya umuvuduko wamaraso muguhuza amavuta no kuyanyuza mumyanya yumubiri kugirango ikorwe umwanda.
Kwiyongera kw'ibinure byatuma amavuta agabanuka mu maraso, bikaba bishobora gutera umuvuduko ukabije w'amaraso.
Isuzuma ry’ubushakashatsi umunani ryanzuye ko chitosan ishobora kugabanya umuvuduko wamaraso ariko ntibigaragara. Ibisubizo byiza byaje mugihe chitosan yakoreshejwe mukigero kinini ariko mugihe gito. Umuvuduko wamaraso wa diastolique (ariko ntabwo umuvuduko wamaraso wa systolique) wagabanutse cyane mugihe chitosan yafashwe mugihe kitarenze ibyumweru 12 kumupanga urenze cyangwa uhwanye na 2,4 g kumunsi.
Nubwo ibisubizo bishobora kugaragara nkibyemeza, ntabwo aribimenyetso bifatika byerekana ko inyongera ya chitosani igabanya umuvuduko wamaraso. Ubushakashatsi bwinshi burakenewe kugirango turusheho gucukumbura isano iri hagati ya chitosan n'umuvuduko w'amaraso.
- Turashobora Gufasha Mugutakaza ibiro
Birashoboka ko ubuzima bukunzwe cyane na chitosan nuko bushobora gufasha kugabanya ibiro. Mugihe hari ibimenyetso bimwe byemeza iki kirego, ni ngombwa kwibuka ko gukoresha inyongera zimirire nkigipimo cyonyine cyo kugabanya ibiro ntabwo byemewe.
Chitosan bikomoka ku bihumyo byakoreshejwe mu igeragezwa rimwe ry’amavuriro ryitabiriwe n’abantu 96 bakuze bashyizwe mu rwego rwo hejuru cyangwa bafite umubyibuho ukabije. Abitabiriye amahugurwa bahawe capsules zirimo umwanya wa 500 cyangwa mg 500 za chitosani basabwa kuzifata inshuro eshanu kumunsi iminsi 90.
Ugereranije na placebo, ibisubizo byerekanaga ko chitosan yagabanije cyane uburemere bwumubiri, indangagaciro zumubiri (BMI), hamwe nipima antropometrike (maraso, imitsi, hamwe n’ibipimo byamavuta) mubitabiriye ubushakashatsi.
Mu bushakashatsi butandukanye, chitosan yagereranijwe na placebo mu bana 61 bashyizwe mubyibushye cyane cyangwa bafite umubyibuho ukabije. Nyuma yibyumweru 12, gukoresha chitosani byatumye kugabanuka k'uburemere bw'umubiri, kuzenguruka mu rukenyerero, BMI, lipide zose, no kwiyiriza isukari mu maraso mu rubyiruko rwitabiriye. Ibisubizo bikekwa ko biterwa nubushobozi bwa chitosan bwo gukuramo ibinure mumitsi yigifu kugirango bisohoke.
Nubwo ibyo bisubizo, ibigeragezo binini byabantu bigomba gukorwa mbere yuko chitosan ishobora gusabwa neza kugabanya ibiro.
- Irashobora Guteza Imbere Gukiza Ibikomere
Bitewe na mikorobe ya mikorobe n'imiterere, hari inyungu zo gukoresha chitosani yibanze mugukiza ibikomere.
Ubushakashatsi bwerekana ko chitosan ifasha mugukiza ibikomere. Chitosan yasanze ifite ingaruka za antibacterial, zingirakamaro mugukiza ibikomere. Byagaragaye kandi ko byongera umuvuduko wo gukwirakwiza uruhu (gukora uruhu rushya).
Vuba aha, abashakashatsi barebye hydrogels ya chitosan, irimo amazi kandi irashobora gukoreshwa kimwe na bande. Hydrogels ya Chitosan irashobora kugabanya ibyago byo kwandura bishobora gufata ibikomere bimwe.
Ikigeragezo giherutse cyagerageje kwambara igikomere cya chitosan kubantu bafite umuriro wo mu rwego rwa kabiri. Kwambara chitosan byagabanije ububabare ndetse nigihe byatwaye kugirango ibikomere bikire. Chitosan kandi wasangaga igabanya ibibazo byanduye.
Mu bundi bushakashatsi buto, imyambarire ya chitosan yakoreshejwe ku bikomere bya diyabete kandi ugereranije n'indi myenda yakomeretse ikozwe mu bice bya nanosilver. Imikorere yimyambarire ya chitosan wasangaga isa ugereranije no kwambara nanosilver. Imyambarire yombi yatumye gukira buhoro buhoro ibikomere bya diyabete kandi birinda n'indwara.
Igipimo: NangaheChitosanNkwiye gufata?
Kugeza ubu, nta mabwiriza ya dosiye yinyongera ya chitosan.
Mu bigeragezo bivura, kunywa chitosan kuva kuri 0.3 g kumunsi kugeza kuri 3,4 g kumunsi kubantu bakuru. Chitosan nayo yakoreshejwe mubyumweru 12 kugeza 13 mubigeragezo.
Birasabwa ko ukurikiza icyerekezo cya dosiye nkuko bigaragara kumurango wongeyeho. Urashobora kandi kubona ibyifuzo bya dosiye kubashinzwe ubuzima.
Kuri AoguBio, twumva akamaro ko gutanga ibisubizo karemano kandi bifatika kubuzima bwiza. Chitosan yacu irageragezwa cyane kugirango isukure kandi ifite imbaraga, iha abakiriya bacu amahoro yo mumutima bazi ko bakoresha ibicuruzwa byizewe kandi byizewe. Hamwe no kwiyemeza kutajegajega kubuziranenge, duharanira kugeza chitosan yacu kubantu bose bashobora kungukirwa numutungo udasanzwe.
Waba ushaka gushyigikira urugendo rwo kugabanya ibiro cyangwa kuzamura ubuzima bwumutima, chitosan itanga igisubizo gisanzwe kandi cyiza. Hamwe nubwitange bwa Aogubio kubwiza nubuziranenge, urashobora kwizera ko inyongera za chitosan zizatanga ibisubizo wifuza. Ongeramo chitosan mubikorwa byawe bya buri munsi kandi wibonere inyungu zidasanzwe. Aogubio yishimiye gutanga ibicuruzwa bidasanzwe kugirango ashyigikire intego zubuzima bwiza.
Kwandika ingingo: Miranda Zhang
Igihe cyo kohereza: Werurwe-01-2024
