Yintoni iChitosan, kwaye isebenza njani?
Ngaba ujonge indlela yendalo yokuxhasa ukunciphisa umzimba kunye namanqanaba asezantsi e-cholesterol? Chitosan yimpendulo yakho.Chitosan , ephuma kwi-chitin (i-fibrous compound efunyenwe ngokuyinhloko kwi-exoskeletons enzima ye-crustaceans kunye nakwiindonga zeeseli ze-fungi ethile), i-supplement enamandla enokunceda ukufezekisa ezi njongo zempilo. Kwi-AOGU Bio, sisebenza ngokukhethekileyo kwimveliso kunye nokusasazwa kwezinto ezisebenza nge-pharmacologically kunye nemathiriyeli ekrwada, kubandakanywa i-chitosan, ukuze isetyenziswe kwizongezelelo zabantu, iimveliso zekhemesti, kunye namayeza, ukutya, i-nutraceutical kunye nemizi mveliso yokuthambisa.
I-Chitosan iveliswa nge-enzymatic reaction eyenza ifom ifaneleke ngakumbi ukuxhaswa. Oku kuthetha ukuba ifunxwa lula ngumzimba, iyenza isebenze ekukhuthazeni ukwehla kobunzima kunye nokunciphisa amanqanaba e-cholesterol. Ingqwalasela ye-Aogubio kwimithombo yendalo kunye nezinzileyo iqinisekisa ukuba i-chitosan yethu ikumgangatho ophezulu kwaye ayinazo izongezo eziyingozi okanye iikhemikhali.
Iinzuzo zeChitosanizongezo
Ngophando lwezenzululwazi, i-chitosan ifunyenwe ine-antimicrobial, i-antioxidant, i-anti-inflammatory, kunye nezinye iipropathi. Ezi zakhiwo zebhayoloji zinokuba luncedo kwiimeko zempilo ezahlukeneyo.
Izifundo ziyaqhubeka nokuvela njengoko abaphandi befunda ngakumbi malunga ne-polysaccharide kunye nokusetyenziswa kwayo okunokwenzeka. Ezinye zeendlela ezinokuthi zisetyenziswe i-chitosan zichazwe ngezantsi.
- Ngamana Yehlisa iSwekile yegazi ePhezulu
I-Chitosan iphakanyiswe njengonyango olongezelelweyo lweshukela ephezulu yegazi, uphawu oluqhelekileyo lwe-syndrome ye-metabolic syndrome (iqela leemeko ezidibeneyo zingakhokelela kwisifo senhliziyo, isifo sikashukela, kunye ne-stroke) kunye nohlobo lwe-2 yeswekile.
Uphononongo lwezilwanyana kunye nelabhoratri lufumene unxibelelwano phakathi kwe-chitosan kunye nokuphuculwa kolawulo lweswekile yegazi ngokuncipha kokunganyangeki kwe-insulin (xa izihlunu, isibindi, kunye neeseli ezinamafutha zingaphenduli kakuhle kwi-insulin kwaye zingenako ukuthatha iswekile egazini, idala imfuno yokuba i-pancreas ikwazi ukumelana ne-insulin. yenza i-insulin eninzi) kunye nokunyuswa kweswekile yegazi ngamathishu. Ezi zibonelelo ziye zavavanywa kwiimvavanyo ezahlukeneyo zonyango.
Uhlalutyo lwe-meta lwezilingo zekliniki ezili-10 zifumene iziphumo eziphikisanayo malunga nokusebenza kwe-chitosan ekwehliseni iswekile yegazi. Ngelixa i-chitosan ibonakala inciphisa iswekile yegazi kunye ne-hemoglobin A1c (HbA1c), uvavanyo lwegazi ukujonga umyinge weswekile yegazi kwiinyanga ezintathu, ayizange ibe nempembelelo ebalulekileyo kumanqanaba e-insulin.
Abaphandi babonisa ukuba iziphumo ezilungileyo zibonwe xa i-chitosan isetyenziswe kwi-dose ye-1.6 ukuya kwi-3 grams (g) ngosuku kwaye ubuncinane kwiiveki ze-13.
Olunye uphando lufumene ukuba i-chitosan inokudlala indima ekuthinteleni isifo seswekile. Kuphononongo, abathathi-nxaxheba abane-prediabetes (xa amanqanaba e-glucose yegazi ephezulu kodwa engekho phezulu ngokwaneleyo ukuba athathwe njengesifo sikashukela) ayenziwa ngokungaqhelekanga ukuba athathe indawo ye-placebo (into engenanzuzo) okanye i-chitosan yokuncedisa iiveki ze-12. Xa kuthelekiswa ne-placebo, i-chitosan iphucule ukudumba, i-HbA1c, kunye namanqanaba eswekile yegazi.
Lilonke, izilingo zabantu kwi-chitosan zolawulo lweswekile yegazi ziyasilela kubungakanani bokufunda kunye noyilo. Uphando olongezelelweyo luyafuneka kule ndawo.
- Isenokwehlisa uxinzelelo lwegazi oluphezulu
Inani elilinganiselweyo lezilingo zeklinikhi libonise ubudlelwane phakathi kwe-chitosan kunye noxinzelelo lwegazi. Ngokukodwa ngakumbi, i-chitosan ifunyenwe yokunciphisa uxinzelelo lwegazi kwizifundo ezincinci zabantu. Nangona kunjalo, ezinye iziphumo zophando ziye zaxutywa.
I-Chitosan kucingelwa ukuba inciphisa uxinzelelo lwegazi ngokuzibophelela ngamafutha kwaye iwathwale ngomgudu wokwetyisa ukuze wenziwe ilindle.
Ukunyuswa kwamafutha amaninzi kuya kukhokelela ekunciphiseni amanqanaba amafutha egazini, umngcipheko woxinzelelo lwegazi oluphezulu.
Uphononongo lwezifundo ezisibhozo lugqibe kwelokuba i-chitosan inokwehlisa uxinzelelo lwegazi kodwa hayi kakhulu. Ezona ziphumo zibalaseleyo zeza xa i-chitosan isetyenziswe kwidosi ephezulu kodwa ngamaxesha amafutshane. Uxinzelelo lwegazi lwe-diastolic (kodwa hayi uxinzelelo lwegazi lwe-systolic) lwehla kakhulu xa i-chitosan ithathwa ngaphantsi kweeveki ze-12 kwiidosi ezinkulu okanye ezilingana ne-2.4 g ngosuku.
Nangona ezi ziphumo zinokubonakala zikholisa, azikho ubungqina obucacileyo bokuba i-chitosan supplementation yehlisa uxinzelelo lwegazi. Uphando olongezelelweyo luyimfuneko ukuphonononga ngakumbi ubudlelwane phakathi kwe-chitosan kunye noxinzelelo lwegazi.
- Ngamana iNceda ngeLohleko lobunzima
Mhlawumbi elona bango lezempilo lidumileyo le-chitosan kukuba linokunceda ekunciphiseni ubunzima. Nangona kukho ubungqina bokuxhasa eli bango, kubalulekile ukukhumbula ukuba ukusebenzisa izongezo zokutya njengomlinganiselo owodwa wokunciphisa umzimba akukhuthazwa.
Chitosan ephuma kwifungi isetyenziswe kulingo lwezonyango olubandakanya abantu abadala abangama-96 abathathwa njengabatyebe kakhulu okanye batyebe kakhulu. Abathathi-nxaxheba banikwa ii-capsules eziqulethe i-placebo okanye i-500 mg ye-chitosan kwaye bacelwa ukuba bathathe amaxesha amahlanu ngosuku ngeentsuku ze-90.
Xa kuthelekiswa ne-placebo, iziphumo zibonise ukuba i-chitosan yanciphisa kakhulu ubunzima bomzimba, i-index mass body (BMI), kunye nemilinganiselo ye-anthropometric (igazi, imisipha kunye nemilinganiselo yamafutha) kubathathi-nxaxheba bophando.
Kuphononongo olwahlukileyo, i-chitosan yafaniswa ne-placebo kubantwana abangama-61 abachazwe njengobunzima okanye ukutyeba. Emva kweeveki ze-12, ukusetyenziswa kwe-chitosan kubangele ukunciphisa ubunzima bomzimba, umjikelezo wesinqe, i-BMI, i-lipids iyonke, kunye nokuzila iswekile yegazi kubathathi-nxaxheba abancinci. Ezi ziphumo kucingelwa ukuba zibangelwe kukukwazi kwe-chitosan ukususa amanqatha kwindlela yokwetyisa ukuze akhuphe.
Ngaphandle kwezi ziphumo, izilingo ezinkulu zabantu kufuneka zenziwe ngaphambi kokuba i-chitosan ikhuthazwe ngokukhuselekileyo ekulahlekeni kobunzima.
- Ngamana Ukukhuthaza ukuPhiliswa kwenxeba
Ngenxa yeempawu zayo zokulwa neentsholongwane kunye nezakhiwo, kukho umdla wokusebenzisa i-chitosan ye-topical ukuphilisa amanxeba.
Uphando lubonisa ukuba i-chitosan inceda kwinkqubo yokuphulukisa isilonda. I-Chitosan ifunyaniswe ineempembelelo zokulwa ne-antibacterial, ezibalulekileyo ekuphulukiseni amanxeba. Ikwafunyaniswe ukuba yonyusa izinga lokukhula kolusu (ukwenziwa kolusu olutsha).
Kungekudala, abaphandi baye bajonga i-chitosan hydrogels, equkethe amanzi kwaye ingasetyenziselwa ngokufanayo kwi-bandages. IChitosan hydrogels inokunciphisa umngcipheko wosulelo olunokuchaphazela amanxeba athile.
Ulingo lwakutsha nje luvavanye ukunxitywa kwenxeba le-chitosan kubantu abatshileyo ngokwenqanaba lesibini. Ukunxitywa kwe-chitosan kwehlisa zombini iintlungu kunye nexesha elithathiweyo ukuba amanxeba aphole. I-Chitosan nayo yafunyanwa ukunciphisa iziganeko zosulelo lwenxeba.
Kwesinye isifundo esincinci, ukunxitywa kwe-chitosan kwasetyenziswa kumanxeba eswekile kwaye kuthelekiswa nesinye isinxibo senxeba esenziwe ngamasuntswana e-nanosilver. Ukusebenza kwe-chitosan yokugqoka kwafunyaniswa kufana xa kuthelekiswa nokugqoka i-nanosilver. Zombini izinxibo zakhokelela ekunyangeni ngokuthe ngcembe amanxeba esifo seswekile kwaye zathintela nosulelo.
Dosage: YimaliniChitosanNdithathe?
Okwangoku, akukho zikhokelo zedosi yezongezo ze-chitosan.
Kwizilingo zeklinikhi, i-chitosan dosing yayisuka kwi-0.3 g ngosuku ukuya kwi-3.4 g ngosuku kubantu abadala. I-Chitosan yayisetyenziswa ngokuqhelekileyo kwi-12 ukuya kwiiveki ze-13 kwizilingo.
Kucetyiswa ukuba ulandele imiyalelo yedosi njengoko kubonisiwe kwileyibhile yokongeza. Unokufumana iingcebiso zedosi kumboneleli wezempilo.
Kwi-AoguBio, siyakuqonda ukubaluleka kokubonelela ngezisombululo zendalo kunye nezisebenzayo kwimpilo kunye nokuba sempilweni. I-chitosan yethu ivavanywa ngokungqongqo ukuqinisekisa ukucoceka kwayo kunye namandla, ukunika abathengi bethu uxolo lwengqondo besazi ukuba basebenzisa imveliso ethembekileyo nethembekileyo. Ngokuzibophelela okungagungqiyo kumgangatho, sizama ukwenza i-chitosan yethu ifumaneke kuye wonke umntu onokuxhamla kwiipropathi zayo ezikhethekileyo.
Nokuba ufuna ukuxhasa uhambo lwakho lokulahleka kobunzima okanye ukuphucula impilo yentliziyo yakho, i-chitosan ibonelela ngesisombululo sendalo nesisebenzayo. Ngokuzinikezela kuka-Aogubio kumgangatho kunye nobunyulu, unokuthemba ukuba izongezo zethu ze-chitosan ziya kuzisa iziphumo ozifunayo. Yongeza i-chitosan kwindlela yakho yemihla ngemihla kwaye ufumane izibonelelo ezimangalisayo ngokwakho. I-Aogubio inebhongo ngokunikezela ngale mveliso ikhethekileyo ukuxhasa impilo yakho kunye neenjongo zempilo.
Ukubhalwa kwenqaku:UMiranda Zhang
Ixesha lokuposa: Mar-01-2024
