I-Apigenin, i-bioflavonoid efumaneka kwiintlobo ngeentlobo zezityalo, ifumene ingqalelo eninzi kwiinzuzo zayo ezininzi zempilo. Ukusuka ekuthinteleni umhlaza ukuya ekudambiseni ixhala, le khompawundi yendalo inoluhlu lweenzuzo zokukhuthaza impilo yonke. Kweli nqaku, sihlola amandla amangalisayo e-apigenin, sifunda ngeempawu zayo, imithombo yendalo, kunye nendima yayo ekuthinteleni izifo.
Kwi-Aogubio, inkampani ekhethekileyo ekuveliseni nasekuhanjisweni kwezinto ezisebenzayo ze-pharmacologically, izinto eziluhlaza kunye nezityalo zezityalo, siyaqaphela ukubaluleka kwe-apigenin kunye nefuthe layo kwimpilo yabantu. Injongo yethu kukubonelela ngeemveliso kwimveliso yamayeza, ukutya, i-nutraceutical kunye ne-cosmetic edibanisa amandla e-apigenin ukuxhasa indlela yokuphila enempilo.
I-Apigenin ihlelwa njenge-bioactive flavonoid kunye noluhlu lweenzuzo zempilo. Enye yeempawu zayo eziphambili yimpembelelo yayo ye-antioxidant, enceda ukulwa noxinzelelo lwe-oxidative kunye nokukhusela iiseli emonakalweni. Ngokunciphisa imiphumo eyingozi ye-radicals yamahhala, i-apigenin ikhuthaza impilo yonke kwaye igcina impilo yezitho ezibalulekileyo.
Ngaphezu koko, i-apigenin ineepropati ezichasayo, iyenza ibe yongezelelo oluxabisekileyo kuyo nayiphi na indlela yempilo yendalo. Ngokunciphisa ukuvuvukala emzimbeni, i-apigenin inokunceda ukukhulula iimpawu ezinxulumene nokuvuvukala okungapheliyo kunye nokuxhasa amajoni omzimba aphilileyo.
Uphononongo lwakutsha nje lufumene ubungqina obubambekayo obudibanisa i-apigenin kuthintelo lomhlaza. Le khompawundi enamandla ibonise ipropathi ethembisayo yomhlaza, inqanda ukukhula kweeseli zomhlaza kunye nokunciphisa umngcipheko wokwakheka kwethumba. Ngokudibanisa ukutya okutyebileyo kwe-apigenin kwisidlo sakho, unokuthatha inyathelo elibalulekileyo eliya kwimpilo egqibeleleyo kwaye unciphise umngcipheko weentlobo ezahlukeneyo zomhlaza.
Ukongeza, i-apigenin ifunyenwe ineziphumo ze-anxiolytic, ezinokuthi zithobe ukuxhalaba kunye nokukhuthaza impilo yengqondo engcono. Le khompawundi yendalo inamandla okulawula amahomoni kwaye ichaphazele i-neurotransmitters, inceda abantu ukuba balwe neempawu zokuphazamiseka kokuxhalaba kunye nokuphucula impilo yabo yonke.
Xa ufaka i-apigenin kwisidlo sakho, kukho imithombo emininzi yendalo ekufuneka uyiqwalasele. Iti ye-Chamomile, eyaziwayo ngeempawu zayo zokuzola, iqulethe ixabiso eliphezulu le-apigenin. Eminye imifuno nemifuno, njengeparsley, icelery, nethyme, nazo zineapigenin yaye zongezelelekileyo ekutyeni okusempilweni okutyebileyo kwiapigenin.
Kuyafaneleka ukuba uqaphele ukuba ngelixa i-apigenin izinzile xa idliwe njengenxalenye yokutya, inokungazinzi xa ihlukaniswe kwimithombo. Ke ngoko, ukudibanisa ukutya okupheleleyo kunye nemithombo yendalo ye-apigenin yeyona ndlela ilungileyo yokuvuna ngempumelelo izibonelelo zayo.
Kwi-Aogubio, injongo yethu kukusebenzisa amandla e-apigenin ngokubonelela ngezondlo ezikumgangatho ophezulu kunye nezongezelelo. Iimveliso zethu ziqulunqwe ngononophelo ukuze kuqinisekiswe idosi echanekileyo kunye nokuhanjiswa kwe-apigenin, ukwandisa inzuzo yayo yezempilo kubathengi bethu.
Imiphumo ye-apigenin kwimpilo yengqondo yenye inkalo ekufanele ihlolwe. Ikhono layo lokunciphisa uxhalaba kunye nokuchaphazela impilo ye-immune inokudlala indima ebalulekileyo ekukhuthazeni impilo yonke kunye nokusebenza kwengqondo. Ngokufaka i-apigenin kubomi bakho bemihla ngemihla, unokuxhasa impilo yengqondo kunye nokuphucula ukusebenza kwengqondo.
Amagqabantshintshi eenzuzo zezempilo ze-apigenin:
- UkuNcitshiswa kokuNcitshiswa
- Umngcipheko wokuNcitshiswa koMhlaza
- Amanqanaba e-NAD aphuculweyo
- Iimvakalelo Ezincitshisiweyo Zokuxhalaba
- Iimvakalelo eziNcitshisiweyo zoxinzelelo
- ICholesterol esezantsi kunye noThintelo lokutyeba
- Ukukhuselwa kwi-Oxidative Stress
- Isiqabu kwi-Rheumatoid Arthritis
- Unyango lweZifo eziziSebenzayo
- Ukuthintelwa kweSifo se-Neurodeergenerative
- Unyango lweMigraines
- Ukuphucula Ukulala
Isebenza njani i-apigenin?
Izifundo zezilwanyana zibonisa ukuba i-apigenin inokuthintela ukuguqulwa kofuzo okwenzekayo kwiiseli ezivezwe kwi-toxins kunye neebhaktheriya.I-Apigenin inokuphinda idlale indima ethe ngqo ekususweni kwee-radicals zamahhala, ukuvinjelwa kwe-enzymes yokukhula kwe-tumor, kunye nokungeniswa kwe-enzymes ye-detoxification efana ne-glutathione. Isakhono se-Apigenin sokuchasa ukudumba sinokuchaza iziphumo zayo kwimpilo yengqondo, ukusebenza kwengqondo, kunye nempendulo ye-immunological, nangona ezinye izifundo ezinkulu zoqwalaselo zingasixhasi esi sigqibo malunga neemeko zemetabolism.
Khumbula ukuba uhlale udibana nengcali yezempilo ngaphambi kokuba wenze naluphi na utshintsho olukhulu kwisidlo sakho okanye uqalise irejimeni entsha yokuncedisa. Banokubonelela ngesikhokelo esixabisekileyo ngokusekelwe kwiimfuno zakho ezithile kunye neenjongo zempilo.
Phakathi kwemikhombandlela emininzi yeziphumo ze-apigenin, kukho iindawo ezine eziphambili eziza kwahlulwa:
Umsebenzi we-Neuroprotective
I-apigenin efumanekayo yokutya inokuthintela ukusebenza kwe-microglia kwaye ibonise umphumo wokukhusela okanye ukulibazisa ukuqala kwe-Alzheimer's disease. Impembelelo ye-neuroprotective ye-apigenin ibonakaliswe kwizifundo ezininzi kwiigundane. Ukongezwa kunye ne-apigenin kwimodeli yegundane yesifo, kuvelise ukuphuculwa kwememori kunye nokufunda kunye nokunciphisa idiphozithi ye-fibrillar amyloid kunye namanqanaba ancitshisiweyo e-peptide ye-beta-amyloid enganyibilikiyo, ekucingelwa ukuba ibalulekile ekuqaliseni nasekuqhubeleni phambili kwe-Alzheimer's disease. Ukongezelela, kwaboniswa ukuba i-apigenin yabangela ukubuyiselwa kwendlela ye-ERK / CREB / BDNF, ebandakanyekayo ekusebenzeni kwememori kwaye ichaphazeleka ngokukodwa yi-Alzheimer's disease. Kwesinye isifundo kwiimpuku ezine-amnesia, i-apigenin iphucule inkumbulo kunye nokusebenza kokufunda kwendawo.
Umsebenzi we-Antitumor
Kwiimvavanyo zezilwanyana, kwaphawulwa ukuba ukusetyenziswa kwe-apigenin ngaphambi nangexesha lokuvezwa kwe-carcinogens, kunciphisa umngcipheko wokuba nomhlaza xa kuthelekiswa neqela elilawulayo apho ukuvezwa kwe-carcinogens akuzange kuhambisane nokusetyenziswa kwe-apigenin. Ukunyuswa okukhethiweyo kwe-tumor cell apoptosis kunye nokuvinjwa kwe-metastasis nako kwabonwa. Iindlela zesenzo esijongene nale nto zifana nezinye ze-flavonoids eziqhelekileyo, ezibizwa ngokuba yi-antioxidation, inhibition of inflammation and cell cycle progression, kunye nenkxaso ye-hepatic detoxification.
Ukongeza, i-apigenin iphucula i-autophagy - inkqubo yendalo yomzimba yokubuyisela "iibhloko zokwakha" kwinqanaba leeselula "ngokuhlaziya" iiseli ezikhutshelwe ngokungachanekanga (ezinokuguqula umhlaza).
Anti-ukuguga umsebenzi
Ngeempembelelo zayo ezichasayo, i-apigenin yi-inhibitor (ikhemikhali ebangela ukuhla kwesantya sokuphendula kweekhemikhali) yeprotheni ye-CD38 - ukuveliswa kwayo (ukwanda kweminyaka) kunxulunyaniswa nokuphendula komzimba ekudumbeni, kunye nokwanda kobukho bakhe. ikhupha unikezelo lomzimba lwe-NAD+-isixhobo esiyimfuneko esifunekayo kuhlaziyo oluchanekileyo lwe-DNA kunye neeseli (amanqanaba azo ehla ngokuguga) - okukhokelela ekugugeni okukhawulezileyo.
Umsebenzi olawulayo kunye ne-anabolic
I-Apigenin ilungisa kakuhle i-GABA (A) i-receptors [1], ekhokelela kwisiphumo sokuzola kunye nokuzola. Ikwathoba i-basal cortisol (igalelo eliphambili kuxinzelelo olungapheliyo)
Ixesha lokuposa: Aug-01-2023
