Ikhutshwe kwintyatyambo ye-Sophora japonica, i-quercetin yi-flavonoid (kunye ngakumbi ngakumbi i-flavonol), i-pigment yombala weentyatyambo, iziqhamo kunye nemifuno. Kuxelwe kuyo inceda ukuvuselela ukusabela komzimba kunye nokulawula ukudumba okugqithisileyo. Isebenza nakwinqanaba le-mitochondrial.
I-Quercetin yi-flavonol esinokuyifumana kwizityalo, kwaye yeyeqela le-flavonoid le-polyphenols. Singayifumana le flavonol kwiziqhamo ezininzi, imifuno, amagqabi, imbewu, kunye neenkozo. Ngokomzekelo, i-capers, i-radish amaqabunga, i-anyanisi ebomvu kunye ne-kale yimithombo yokutya eqhelekileyo equka isixa esixabisiweyo se-quercetin. Le nto inencasa ekrakrayo kwaye iluncedo kwizongezo zokutya, iziselo, kunye nokutya njengesithako.
Ifomula yekhemikhali ye-quercetin yi-C15H10O7. Ngoko ke, sinokubala ubunzima be-molar yale khompawundi njenge-302.23 g / mol. Ngokuqhelekileyo kwenzeka njengomgubo wekristale ophuzi. Ngokuqhelekileyo, lo mgubo awunyibiliki emanzini. Kodwa iyanyibilika kwizisombululo zealkaline.
I-Quercetin dihydrate yi-chemical compound ene-chemical formula C15H14O9. Le nto idla ngokufumaneka kwizongezo zequercetin. Ineyona bioavailability ephezulu phakathi kwezinye izithako. Le nto iphinda iqinisekise ukufunxwa ngcono kwesongezo. Nangona kunjalo, kubiza ngaphezu kwezinye iifom zokuncedisa ngenxa yolu mgangatho wokufunxa okuphezulu. Ukongeza, sinokuthenga i-quercetin dihydrate powder ecocekileyo njengoko sifuna. Iifom ezinomgubo zifanelekile ukuba sikhetha ukusela i-smoothie ngaphezu kweepilisi zokugwinya okanye ukuze sigweme ukugaywa kwempahla ye-cellulose capsule. Ifomu yomgubo we-quercetin dihydrate ibonakala kumbala oqaqambileyo otyheli.
Uninzi lwezithako ze-quercetin kwiimarike zikwifom ye-quercetin dihydrate. I-Quercetin anhydrous kunye ne-dihydrate iyahluka ngobungakanani bamanzi aqulethwe. I-Quercetin anhydrous iqulethe kuphela i-1% ukuya kwi-4% yomswakama kunye neemolekyuli zeswekile ezifakwe kwi-quercetin kwimo yazo yendalo zikhutshwe. Oku kuguqulela kwi-13% ngaphezulu kwe-quercetin ngegram ye-quercetin anhydrous vs quercetin dihydrate. Kubenzi befomula, oku kuthetha ukuba kukho
Uphando lunxulumanise iipropathi ze-quercetin ze-antioxidant kwiinzuzo ezahlukeneyo zempilo ezinokubakho.
Nazi ezinye zeenzuzo zayo eziphezulu ezisekwe kwisayensi:
- Isenokuba neziphumo zomhlaza
Ngenxa yokuba i-quercetin inezixhobo zokulwa nomhlaza, inokuba neempawu zokulwa nomhlaza.
Kuphononongo lwetyhubhu yovavanyo kunye nezifundo zezilwanyana, i-quercetin yafunyanwa icinezela ukukhula kweeseli kwaye ibangele ukufa kweeseli kwiiseli zomhlaza wedlala lesinyi.
Olunye uvavanyo lwetyhubhu kunye nophononongo lwezilwanyana lwaqaphela ukuba ikhompawundi ineziphumo ezifanayo kwisibindi, imiphunga, ibele, isinyi, igazi, ikholoni, i-ovarian, i-lymphoid, kunye neeseli zomhlaza we-adrenal.
Nangona ezi ziphumo zithembisa, izifundo zabantu ziyafuneka phambi kokuba i-quercetin inconywe njengonyango olulolunye lomhlaza.
- Inokunciphisa ukuvuvukala
Iiradicals zasimahla zinokwenza okungakumbi kunokonakalisa nje iiseli zakho.
Uphando lubonisa ukuba amanqanaba aphezulu eeradicals zasimahla anokunceda ukwenza iijene ezikhuthaza ukudumba. Ke, amanqanaba aphezulu eeradicals zasimahla anokukhokelela ekwandeni kwempendulo yokuvuvukala.
Nangona ukudumba okuncinane kuyimfuneko ukuze uncede umzimba wakho uphile kwaye ulwe nosulelo, ukudumba okuzingileyo kunxulunyaniswa neengxaki zempilo, kuquka umhlaza othile, kunye nesifo sentliziyo nezintso .
Uphononongo lubonisa ukuba i-quercetin inokunceda ukunciphisa ukuvuvukala.
Kwizifundo zovavanyo-ityhubhu, i-quercetin yanciphisa iimpawu zokuvuvukala kwiiseli zomntu, kuquka i-molecule ye-tumor necrosis factor alpha (TNFα) kunye ne-interleukin-6 (IL-6).
Uphononongo lweeveki ezisi-8 kubafazi abangama-50 abane-rheumatoid arthritis baphawule ukuba abathathi-nxaxheba abathathe i-500 mg yequercetin bafumana ubunzima obukhulu kwasekuseni, iintlungu zasekuseni, kunye neentlungu zasemva komsebenzi.
Kwakhona baye banciphisa iimpawu zokuvuvukala, ezifana ne-TNFα, xa kuthelekiswa nalabo bafumana indawo ye-placebo.
Ngelixa ezi zinto zifunyanisiweyo zithembisa, uphando oluninzi lwabantu luyafuneka ukuze kuqondwe iipropathi ezinokuthi zibe kho zokuchasa ukudumba.
- Isenokwenza lula iimpawu zokwaliwa
Iipropathi zeQuercetin ezinokuthi zichase ukudumba zinokubonelela ngesiqabu seempawu zokungalungelani nokwaliwa.
Uvavanyo lwetyhubhu kunye nezifundo zezilwanyana zifumanise ukuba zinokuvala ii-enzymes ezibandakanyekayo ekudumbeni kwaye zicinezele iikhemikhali ezikhuthaza ukudumba, njenge-histamine.
Ngokomzekelo, uphando oluthile lubonise ukuba ukuthatha izongezo ze-quercetin kucinezele ukusabela kwe-anaphylactic ezinxulumene ne-peanut kwiimpuku.
Kusenjalo, akucaci ukuba ikhompawundi inefuthe elifanayo kwi-allergies ebantwini, ngoko ke uphando oluninzi luyafuneka phambi kokuba lunokucetyiswa njengolunye unyango.
- Usenokuthoba umngcipheko wokuphazamiseka kwengqondo okungapheliyo
Uphando lucebisa ukuba iipropathi ze-quercetin ze-antioxidant zinokunceda ukukhusela ukuphazamiseka kwengqondo okuwohlokayo, njengesifo sika-Alzheimer kunye nesifo sengqondo esiyingozi.
Kolunye uphononongo, iimpuku ezinesifo se-Alzheimer zafumana inaliti ye-quercetin rhoqo ngeentsuku ezi-2 kwiinyanga ezi-3.
Ekupheleni kophononongo, iinaliti zazizitshintshile iimpawu ezininzi ze-Alzheimer's, kwaye iimpuku zenze ngcono kakhulu kwiimvavanyo zokufunda.
Kwesinye isifundo, ukutya okutyebileyo kwe-quercetin kunciphise iimpawu zesifo se-Alzheimer kunye nokuphucula ukusebenza kwengqondo kwiimpuku kwinqanaba eliphakathi lemeko.
Nangona kunjalo, ukutya kwakunempembelelo encinci kwizilwanyana ezine-Alzheimer's isigaba esiphakathi.
Ikofu sisiselo esithandwayo esidityaniswe nengozi ephantsi yesifo i-Alzheimer's.
Enyanisweni, uphando lubonisa ukuba iquercetin, ingeyiyo icaffeine, yeyona nto iphambili kwikofu enoxanduva lokuzikhusela kwesi sigulo .
Nangona ezi ziphumo zithembisa, uphando olungakumbi ebantwini luyafuneka.
- Inokunciphisa uxinzelelo lwegazi
Uxinzelelo lwegazi oluphezulu luchaphazela i-1 kwi-3 yabantu abadala baseMelika. Iphakamisa umngcipheko wakho wesifo senhliziyo - eyona nto ibangela ukufa e-United States (24).
Uphando lubonisa ukuba i-quercetin inokunceda ukunciphisa amanqanaba oxinzelelo lwegazi. Kuphononongo lwetyhubhu yovavanyo, ikhompawundi ibonakala inefuthe lokuphumla kwimithambo yegazi.
Xa iimpuku ezinoxinzelelo lwegazi oluphezulu zinikwa i-quercetin imihla ngemihla kwiiveki ze-5, ixabiso labo le-systolic kunye ne-diastolic yegazi (amanani aphezulu nangaphantsi) ancipha ngomlinganiselo we-18% kunye ne-23%, ngokulandelanayo.
Ngokufanayo, ukuphononongwa kwezifundo ze-9 zabantu kwi-580 abantu bafumanisa ukuba ukuthatha ngaphezu kwe-500 mg ye-quercetin kwifom yokuncedisa imihla ngemihla kunciphisa uxinzelelo lwegazi lwe-systolic kunye ne-diastolic ngomlinganiselo we-5.8 mm Hg kunye ne-2.6 mm Hg, ngokulandelanayo.
Nangona ezi zinto zifunyanisiweyo zithembisa, uphando oluninzi lwabantu luyafuneka ukumisela ukuba ikhompawundi inokuba lolunye unyango kumanqanaba aphezulu oxinzelelo lwegazi.
Unokuthenga i-quercetin njengesongezelelo sokutya kwi-intanethi nakwiivenkile zokutya okunempilo. Ifumaneka ngeendlela ezininzi, kuquka iipilisi kunye nomgubo.
Iidosi eziqhelekileyo zivela kwi-500-1,000 mg ngosuku
Ukuba unomdla, nceda uzive ukhululekile ukuqhagamshelana ne-XI'AN AOGU BIOTECH !
Ixesha lokuposa: Mar-07-2023
