I-OEM ODM Healthcare Supplements Choline Glycerophosphate Alpha-GPC Alpha GPC Capsule
Iyini i-Alpha GPC?
I-Alpha-GPC iyilungu lomndeni we-phospholipid, njengenye yezinto eziphuma ku-phosphatidylcholine, edlala indima ebalulekile empilweni ye-membrane yeseli.
Umsebenzi oyinhloko we-physiological we-Alpha-GPC ukuwela umgoqo wegazi nobuchopho futhi unikeze i-choline edingekayo ye-biosynthesis ye-acetylcholine ne-phosphatidylcholine.
I-Alpha-GPC yaziwa ngemiphumela yayo empilweni yobuchopho, ukunaka, ukugxilisa ingqondo, nokwenza inkumbulo.
Sethula umkhiqizo wethu wezempilo oguquguqukayo i-Glyceryl Phosphatidylcholine. Kubalulekile ukuqaphela ukuthi lo mkhiqizo awuhloselwe ukuthatha indawo yemithi yesifo, kodwa ungasiza ngokuqinisekile ukuthuthukisa izimpawu ezihlukahlukene. Isithako sayo esiyinhloko, i-lecithin, sinamandla amangalisayo.
I-Lecithin, eyaziwa nangokuthi i-lecithin, iyinto enamafutha aphuzi ansundu etholakala ezicutshini zezilwane nezitshalo kanye nesikhuphashi seqanda. Iqukethe i-phosphoric acid, i-choline, i-fatty acids, i-glycerol, i-glycolipids, i-triglycerides ne-phospholipids. Lezi zingxenye zidlala indima ebalulekile emizimbeni yethu, njengokwenza ulwelwesi lwamaseli, ukusekela i-alveolar surfactant, ama-lipoprotein ne-bile. I-Lecithin inomthwalo wemfanelo wokukhiqiza izithunywa ze-lipid ezifana ne-lysophosphatidylcholine, i-phosphatidic acid, i-diglycerides, i-lysophosphatidic acid, ne-arachidonic acid.
Lesi sengezo sezempilo esimangalisayo siqukethe i-L-alpha Glycerophosphorylcholine, eyaziwa nangokuthi i-Alpha-GPC noma i-Alphosphocholine. Kuyinhlanganisela yemvelo ye-choline eningi ebuchosheni. Esinye sezici zayo eziphawuleka kakhulu ikhono layo lokusebenza njengesandulela se-acetylcholine, i-neurotransmitter edlala indima ebalulekile ekusebenzeni kwengqondo.
Okwenza umkhiqizo wethu uhluke yikhono lawo eliyingqayizivele lokuletha ngokushesha i-choline ngaphesheya komgoqo wegazi nobuchopho. Lokhu kubalulekile empilweni nasekusebenzeni kobuchopho okuphelele. I-Alpha-GPC iyisandulela se-biosynthetic ye-acetylcholine, okusho ukuthi isiza ukukhiqiza le neurotransmitter ebalulekile. Ngokwenza kanjalo, isekela inkumbulo, ukugxilisa ingqondo, nokusebenza kwengqondo okuphelele.
Nakuba kubalulekile ukuqonda ukuthi umkhiqizo wethu awuthathi indawo yemithi elapha lesi sifo, uyindlela yokwelapha ewusizo. I-Glycerophosphatidylcholine iqukethe i-lecithin enamandla ethuthukisa ukuphuma kwe-cholesterol ku-bile. Lokhu kusiza inqubo ye-lipoprotein metabolism futhi kufinyelele umphumela wokuqedwa omangalisayo. Ngakho-ke, ingathuthukisa izimpawu ezibangelwa i-atherosclerosis, isifo esibonakala ngokuqina nokuncipha kwemithambo.
Ngaphezu kwalokho, imikhiqizo yethu ingasiza futhi ukukhulula izimpawu ezibangelwa isibindi esinamafutha. Isibindi esinamafutha yisifo lapho amafutha anqwabelana khona emangqamuzaneni esibindi, okuholela ekungasebenzi kahle kwesibindi kanye nezinkinga. Ngokusebenzisa i-Glycerophosphatidylcholine, izimpawu zomuntu zilindeleke ukuba zithuthuke ngenxa yezinzuzo ezinikezwa i-lecithin.
Ngokuphawulekayo, sinikeza i-α-GPC powder kanye namaphilisi e-α-GPC ukuze kube lula kuwe. Khetha ifomethi evumelana kangcono nezintandokazi zakho nezidingo zakho, kodwa qiniseka ukuthi zombili izinketho zinikeza izinzuzo ezifanayo ezimangalisayo.
Sengiphetha, i-Glyceryl Phosphatidylcholine ingumkhiqizo wezempilo ophumelelayo ohlanganisa amandla e-lecithin nezinto ezimangalisayo ze-alpha-GPC. Nakuba ingeyona indawo yemithi, ingasiza ekuthuthukiseni izimpawu ezihlukahlukene ezihambisana nesifo sokuqina kwemithambo yegazi nesibindi esinamafutha. Ngekhono layo elimangalisayo lokuletha i-choline ebuchosheni, isekela ukusebenza kwengqondo, inkumbulo nokugxila. Izwa izinzuzo ezinikezwa yilo mkhiqizo omuhle futhi uthathe isinyathelo esiholela ekuthuthukiseni impilo yakho iyonke.
kungani sikhetha i-Alpha-GPC, hhayi i-Beta-GPC?
I-Beta-glycerylphosphocholine(Beta-GPC) iyilungu le-phosphocholines.
I-Beta-GPC inikela kancane kakhulu kungqikithi ye-GPC(~1%), kuyilapho i-Alpha-GPC i-hydrolyzed ku-phosphorylcholine futhi inikela ekuhlinzekweni kwe-choline edingwa isibindi ne-choline edingekayo ukuze kuhlanganiswe i-myelin.
Isebenza kanjani i-Alpha GPC?
Lapho umzimba womuntu uthatha i-Alpha-GPC, ubola ube yi-choline ne-glycerophosphate ngaphansi kwesenzo sama-enzyme emzimbeni. Phakathi kwabo, i-choline ibamba iqhaza ku-biosynthesis ye-acetylcholine, okuwuhlobo lwe-neurotransmitter; I-glycerophosphate i-lecithin Derivatives, ebandakanyeka ekuhlanganiseni i-lecithin.
Imiphumela eyinhloko ye-pharmacological ye-Alpha-GPC ihlanganisa ukuvikela umzimba we-choline; ukuqinisekisa ukuhlanganiswa kwe-acetylcholine ne-lecithin kulwelwesi lwezinzwa, ukuthuthukisa ukujikeleza kwegazi; ukuthuthukisa izimpendulo zengqondo nezokuziphatha ezigulini ezinama-capillaries obuchopho ahlukumezekile.
I-Alpha-GPC VS CDP Choline(Citicoline) VS Phosphatidylserine
Kusuka emthonjeni, i-Alpha-GPC ingatholakala ngokwemvelo ku-lecithin kabhontshisi wesoya, noma ingenziwa ngomzila wokwenziwa; I-CDP Choline ngokuyinhloko iwumzila wokwenziwa; I-phosphatidylserine (PS) ingatholakala ku-lecithin kabhontshisi wesoya, i-sunflower lecithin, njll.
Ngokusebenza ngempumelelo, i-CDP Choline isetshenziswa ngokuyinhloko njenge-metabolism yobuchopho kanye ne-neuroactivator, engakhuthaza ukuphefumula kwamangqamuzana obuchopho, ithuthukise ukusebenza kobuchopho, ithuthukise umsebenzi wesistimu yokuqalisa yesakhiwo esikhuphukayo se-reticular, ikhuthaze ukutakula, futhi inciphise ukumelana ne-cerebrovascular; I-Phosphatidylserine futhi Ibizwa nge-compound nervonic acid, okuyingxenye esebenzayo ye-membrane yeseli. Umphumela wawo uwukuthuthukisa ukusebenza kwamangqamuzana ezinzwa, ukulawula ukuqhutshwa kwemizwa yezinzwa, nokuthuthukisa ukusebenza kwenkumbulo yobuchopho. Ngenxa ye-lipophilicity yayo eqinile, ingangena ngokushesha ebuchosheni ngomgoqo wegazi nobuchopho ngemva kokumuncwa, ithobe amangqamuzana emisipha abushelelezi emithambo futhi andise ukuhlinzekwa kwegazi ebuchosheni.
Izinto ezintathu ezishiwo ngenhla zaziwa ngezinzuzo zazo zokuqonda njengokusekela inkumbulo, ukusebenza kwengqondo, nokugxila.
Imininingwane yethu ye-Alpha-GPC
- I-Alpha GPC 50 powder 25kg/Drum
- I-Alpha GPC 50% granule 25kg/Drum
- I-Alpha GPC liquid 85% 25kg/Drum
- I-Alpha GPC powder 99% 1kg/Isikhwama 25kg/Isigubhu
- I-Alpha-GPC softgel/Alpha-GPC capsule/Alpha-GPC tablet
Yiziphi Izinzuzo zokuthatha i-Alpha GPC?
I-Alpha-GPC iyisengezo se-nootropic esisetshenziswa kabanzi, izinzuzo eziyinhloko zifaka:
Vikela impilo yobuchopho
Sonke siyazi ukuthi i-Alpha GPC iyisandulela se-acetylcholine, esithuthukisa ukudluliswa kwe-cholinergic ebuchosheni. Ikakhulukazi ngokusebenzisa indlela yesenzo i-Alpha GPC ikhulisa ngokuqondile ukuhlanganiswa kanye nokukhishwa kwe-acetylcholine, kangcono kunanoma iyiphi enye inhlanganisela ehlobene ne-choline, ethinta ukugxila kwe-choline ohlelweni lonke nasebuchosheni.
I-Alpha GPC ingamelana nokuguga kobuchopho ngokwandisa amasayithi e-cholinergic receptor, ukubuyisela i-bioavailability ye-acetylcholine, ukwandisa ama-receptor factor factor ebuchosheni, kanye nokunciphisa izinguquko ezingathandeki zesakhiwo ebuchosheni.
I-Alpha GPC iphinde isebenzele ukuthuthukisa ukusebenza kwengqondo nokuthuthukisa inkumbulo nokufunda ngokulwisana nokulahlekelwa okuhlobene neminyaka kwamaseli ezinzwa nemicu ebuchosheni.
Imithamo ephezulu (1200 mg) ye-Alpha-GPC iyasebenza esifweni se-Alzheimer's esimaphakathi kuya kwesimaphakathi futhi isebenza kahle ngokwelashwa okujwayelekile (i-acetylcholinesterase inhibitors).
Khulisa ukusebenza kwemisipha nokugijima
Obunye ubufakazi bokuqala bubonisa ukuthi i-Alpha GPC inamandla okusekela ukusebenza kobuchopho obunempilo kanye nokukhululwa kwe-somatotrophin (hGH). futhi iyakwazi ukuthuthukisa ukukhiqizwa kwe-hormone yokukhula okunamandla kanye nokukhishwa kwamandla ngesikhathi sokuzivocavoca. Ukwanda kokukhiqizwa kwe-hormone yokukhula namandla okukhipha amandla kungakhuphula imisipha futhi kuthuthukise umsebenzi we-metabolic jikelele, ngaleyo ndlela kuthuthukise ukusebenza kwemisipha nokusebenza kwezemidlalo.
Ucwaningo luphinde lubike ukuthi imithamo eyodwa ephakeme kancane ye-600mg-800mg ingase ibe nenzuzo enkulu uma i-Alpha GPC ithathwa ngaphambi kokuzivocavoca (njengesithasiselo sangaphambi kokujima).
Kafushane, i-Alpha-GPC inemisebenzi emibili eyinhloko:
- Umphumela ophakathi: ngcono ukuwohloka komqondo; ukuthuthukisa ikhono lokufunda; vimbela ukukhiqizwa kwamahomoni okucindezeleka
- Umphumela we-peripheral: khuthaza ukukhiqizwa kwe-hormone yokukhula; ngcono ukusebenza kwesibindi; ukungatheleleki kanye nekhono lokulungisa ngesikhathi sokulimala.
Izicelo ze-Alpha-GPC:
Emkhakheni wezokwelapha, amalungiselelo e-Alpha-GPC ikakhulukazi amalungiselelo omlomo (amaphilisi, amaphilisi). Ngokwezibalo, usayizi wemakethe yokulungiselela i-GPC yomhlaba wonke ngo-2020 cishe uyizigidi ezingama-347 zamadola aseMelika. Izinkampani ezifana ne-DAEWOONG, CHONG KUN DANG, ITALFARMACO, njll
Emkhakheni wemikhiqizo yezempilo, ikakhulukazi izithasiselo zokudla. Ngokwezibalo, usayizi wemakethe yomhlaba wonke wemikhiqizo yezempilo equkethe i-Alpha-GPC ngo-2020 icishe ibe yizigidi eziyi-105 zamadola aseMelika, izinhlobo ezidumile ezifana neDokotela Elingcono Kakhulu, Ukudla Kwamanje, njll.
Imithetho Yamazwe Ayinhloko ye-Alpha-GPC:
USA GRASS
I-Alpha-GPC inesimo 'Sokuqashelwa Ngokujwayelekile Njengephephile' (i-GRAS) njengesithako esiphuzweni nasekudleni uma kusetshenziswa ezingeni elingeqile ku-196.2 mg/umuntu/usuku.
E-Europe, i-Alpha GPC umuthi ohlanganisiwe wamandla kadokotela onikezwa iziguli ze-Alzheimer ngemithamo engu-1,200 mg.
E-Korea, i-Alpha GPC(Choline alfoscerate) ifakiwe ku-Korean Pharmacopoeia (KPC).
Umthamo onconyiwe:
Ngokuvamile, sibona ukuthi kumikhiqizo eminingi yezithako ze-GPC, umthamo onconywayo ngu-300-600 mg, kodwa ngezimpawu ezahlukene kanye nabasebenzisi, umthamo wansuku zonke we-400-1200mg nawo ufanelekile.
