Ukwembula Isithako Esiyimfihlo: I-Kojic Acid Dipalmitate Yokukhanyisa Ithoni Yesikhumba Engalingani
Ukwembula Isithako Esiyimfihlo: I-Kojic Acid Dipalmitate Yokukhanyisa Ithoni Yesikhumba Engalingani
Ekuphishekeleni isikhumba esingenasici nesikhazimulayo, abantu abaningi baphendukela ezimangalisweni zezithasiselo ze-skincare. Isithako esinjalo ebesilokhu sigqama eminyakeni yamuva nje i-Kojic Acid Dipalmitate. Lesi sengezo esimhlophe sesizukulwane esisha sivele njengesiguquli segeyimu ngemuva kwe-arbutin ne-kojic acid, ethembisa imiphumela emangalisayo ekukhanyeni ithoni yesikhumba engalingani. Ake sijule ngezinzuzo nokusetshenziswa kwe-Kojic Acid Dipalmitate.
I-Kojic Acid Dipalmitate, eyaziwa nangokuthi i-KAD-15, isiguqule imboni ye-skincare ngezakhiwo zayo ezimangalisayo zokuvuselela isikhumba. Ikhiqizwe futhi yasatshalaliswa ngu-Aogubio, inkampani ekhethekile ezintweni ezisebenza ekhemisi, izinto ezingavuthiwe, nezikhishwe zezitshalo, le nhlanganisela isethwe ukuze ichaze kabusha indlela esibhekana ngayo nokunakekelwa kwesikhumba. I-Aogubio izinikele ekuhlinzekeni ngemikhiqizo yekhwalithi ephezulu yezimboni zemithi, zokudla, ezomsoco, nezimonyo, iqinisekisa ukuthi amakhasimende ayo awatholi lutho ngaphandle kokungcono kakhulu.
Ngakho-ke, yini eyenza i-Kojic Acid Dipalmitate ihluke kwabangaphambi kwayo? Impendulo ilele ekusebenzeni kwayo okungenakuqhathaniswa ekuvimbeleni umsebenzi we-tyrosinase, obhekele ukukhiqizwa kwe-melanin. Ngokuhlanganisa i-Cu2+ futhi ivimbele ukwakheka kwe-melanin, i-KAD-15 ifinyelela izinga elisebenzayo elimangalisayo elingaphezu kwama-80%. Lokhu kuyenza isebenze kahle kakhulu futhi ibe mhlophe esebenza ngokuzinzile, idlule lokho okulindelwe ngabathengi emhlabeni jikelele.
Akukhona nje ukuthi i-Kojic Acid Dipalmitate ihamba phambili ngamakhono ayo okwenza abe mhlophe, kodwa futhi inikeza inqwaba yezinye izinzuzo. Uma ihlanganiswe novithamini C ethyl ether kanye ne-arbutin, yakha ifomula enamandla elwa nokushintsha umbala nokungalingani kwesikhumba. Lezi zinhlanganisela zisebenza ngokubambisana ukuze zinikeze isisombululo esiphelele, siqinisekisa ukuthi isikhumba sihlala sikhazimula futhi silingana.
Imikhiqizo yezimonyo equkethe i-Kojic Acid Dipalmitate ijabulela imiphumela ye-antioxidant ne-sunscreen, okuyenza ibe yinketho ephezulu kubantu abafuna ukuvikela isikhumba sabo ezintweni eziyingozi njengemisebe ye-UV nama-radicals mahhala. Imisebe yelanga nezinto ezingcolisa indawo ezungezile kwaziwa ukuthi kunesandla ekugugeni kwesikhumba, okuholela ekubeni ibala libe buthuntu futhi lintule. Ngokufaka i-KAD-15 ezinhlelweni zokunakekelwa kwesikhumba, abantu banganciphisa inqubo yokuguga, bathuthukise ukuthungwa kwesikhumba sabo nokunwebeka.
Kulabo abazabalaza ne-hyperpigmentation namachashazi amnyama, i-Kojic Acid Dipalmitate iveza isisombululo esisha. Kungakhathaliseki ukuthi kubangelwa izibazi zezinduna, ukulimala kwelanga, noma izinguquko zamahomoni, lokhu kungahambi kahle kwemibala kungase kubangele ukukhungatheka kubantu abaningi. I-KAD-15 ye-Aogubio inikeza umsebe wethemba ngokunciphisa ngokuphumelelayo ukubukeka kwalezi ziphazamiso, ukubuyisela ibala lobusha kanye nebala.
Mhlawumbe esinye sezici ezikhanga kakhulu ze-Kojic Acid Dipalmitate iphrofayili yayo yokuphepha. Ngemithetho eqinile embonini yezimonyo, ukuqinisekisa ukuphepha kanye nenhlalakahle yabathengi kubaluleke kakhulu. I-Aogubio iyasivuma lesi sibopho futhi isihlole ngokuqinile le nhlanganisela ukuze iqinisekise ukuphepha kwayo ukuze isetshenziswe abantu. Ngokunamathela ezinyathelweni eziqinile zokulawula ikhwalithi, i-Aogubio iqinisekisa ukuthi amakhasimende angayithemba imikhiqizo ayithengayo.
Ezweni elihlala livela lokunakekelwa kwesikhumba, i-Kojic Acid Dipalmitate igqama njengesithako sempumelelo ekukhanyiseni ithoni yesikhumba engalingani. Ngekhono layo elimangalisayo lokuvimbela umsebenzi we-tyrosinase, ukuvimbela ukwakheka kwe-melanin, nokuhlinzeka ngemiphumela ye-antioxidant ne-sunscreen, le nhlanganisela inikeza isisombululo esiphelele kubantu abafuna umbala okhanyayo. Ngokuzinikezela kuka-Aogubio ekukhiqizeni imikhiqizo yekhwalithi ephezulu, abathengi bangagcina bedalule imfihlo yokuzuza isikhumba esingenasici nesikhanyayo.
Incazelo Yemikhiqizo
I-Kojic acid dipalmitate i-modified kojic acid derivative, engagcini nje ngokunqoba ukuntengantenga kokukhanya, ukushisa kanye ne-iron eyinsimbi, kodwa futhi igcina umsebenzi ovimbelayo we-tyrosinase futhi ivimbele ukwakheka kwe-melanin. I-Kojic dipalmitate iphethe impahla yamakhemikhali ezinzile. Ngeke ijike ibe phuzi uma isetshenziselwa i-oxidation, i-metallic ion, ukukhanya nokushisa.
Umsebenzi
- I-kojic acid dipalmitate iwuhlobo lwesivimbeli esikhethekile se-melanin. Ingavimbela umsebenzi we-tyrosinase ngokuhlanganisa i-ion yethusi kumaseli ngemva kokungena kumaseli esikhumba. I-Kojic acid nokuphuma kwayo kunomphumela ongcono wokuvimbela i-tyrosinase kunanoma iyiphi enye i-ejenti emhlophe yesikhumba.
- I-kojic acid dipalmitate ingaphinda iqede i-radical yamahhala, iqinise ukusebenza kwamaseli futhi igcine ukudla kukusha.
UKUHLAZIYWA OKUSISEKELO
| UHLAZIYO | INKCAZO | IMIPHUMELA |
| Ukubukeka | Impushana Emhlophe | Iyahambisana |
| Iphunga | Isici | Iyahambisana |
| Kunambithile | Isici | Iyahambisana |
| Isivivinyo | 99% | Iyahambisana |
| Sieve Analysis | I-100% idlula i-80 mesh | Iyahambisana |
| Ukulahlekelwa Ekumisweni | 5% Ubukhulu. | 1.02% |
| Umlotha one-sulphate | 5% Ubukhulu. | 1.3% |
| Khipha i-Solvent | I-Ethanol Namanzi | Iyahambisana |
| Insimbi Enzima | 5 ppm Max | Iyahambisana |
| Njengoba | 2ppm Max | Iyahambisana |
| Izincibilikisi Ezisele | 0.05% Ubukhulu. | Okubi |
| I-Microbiology | ||
| Inani Lepuleti Eliphelele | 1000/g Ubukhulu | Iyahambisana |
| Imvubelo & Isikhunta | 100/g Ubukhulu | Iyahambisana |
| E.Coli | Okubi | Iyahambisana |
| I-Salmonella | Okubi | Iyahambisana |
Izinhlelo zokusebenza
Amathoni okunakekela umzimba/ubuso, izinto zokulwa nokuguga, ukuvikela ilanga, ngemva kokushona kwelanga nokuzishuka, ukucwenga kwesikhumba/ukukhanya, ukwelapha izimo ezihlukahlukene zesikhumba ezishintsha umbala obala noma izinkinga, isb ama-solar lentigene, i-melasma, i-chloasma, izibazi, amabala, ubudala be-pigment nezinye izindawo zesikhumba ezinombala ogqamile
