Uyisebenzisa njani i-Kojic Acid Dipalmitate
Indlela yokusebenzisa i-Kojic Acid Dipalmitate: Isikhokelo esiBanzi
I-Kojic acid dipalmitate sisithako esinamandla esiqhele ukusetyenziswa kushishino lwezithambiso ukwenzela ukukhanyisa ulusu kunye neempawu ezikhanyayo. Ithatyathwe kwi-asidi ye-kojic, le khompawundi iye yanconywa ngokubanzi ngokukwazi kwayo ukunciphisa inkangeleko ye-hyperpigmentation, amabala ebudala, kunye nolunye utshintsho lwesikhumba. Nangona kunjalo, ukubandakanya i-kojic acid i-dipalmitate kwi-cosmetic formulations ingaba ngumngeni ngenxa yokuthambekela kwayo ukwenza iikristali ezihamba phambili. Kweli nqaku, siza kuphonononga ukusetyenziswa okufanelekileyo kwe-kojic acid dipalmitate kwaye sinikeze isikhokelo senyathelo nenyathelo malunga nendlela yokuyifaka ngempumelelo kwindlela yakho yokhathalelo lwesikhumba.
Phambi kokuphonononga kusetyenziso lwe-kojic acid dipalmitate, makhe sijonge ngokufutshane inkampani esemva kwesi sithako sivelisa izinto ezintsha. I-Aogubio yinkampani ekhethekileyo evelisa kwaye isasaze izinto ezisebenzayo ze-pharmacologically, izinto eziluhlaza, i-extracts yezityalo, i-nutraceuticals, kunye nezinye iimveliso kumashishini ahlukeneyo, kubandakanywa amayeza, ukutya, isondlo kunye ne-cosmetic. Ngokugxila ekuhambiseni izithako eziphezulu, i-Aogubio izenzele njengomboneleli othembekileyo kwimarike.
Ngoku, masingene kusetyenziso lwe-kojic acid dipalmitate. Ukuze unqobe umngeni we-crystallization, kucetyiswa ukuba udibanise i-isopropyl palmitate okanye i-isopropyl myristate kwisigaba seoli esiqulethe i-kojic acid dipalmitate. Oku kuya kunceda ukunyibilikisa i-dipalmitate kunye nokukhusela ukubunjwa kweekristale ezingafunekiyo. Nantsi isikhokelo senyathelo nenyathelo sendlela yokusebenzisa ngokufanelekileyo i-kojic acid dipalmitate kuqulunqo lwakho lokhathalelo lwesikhumba:
1. Qokelela izithako kunye nezixhobo ezifunekayo:
- Kojic acid dipalmitate
-Isopropyl palmitate okanye isopropyl myristate
- Izithako zesigaba seoli
- Izithako zesigaba samanzi
- Izikhongozeli ezikwaziyo ukumelana nobushushu
- Izixhobo zokufudumeza
2. Qala ngokulungiselela isigaba seoli:
- Yongeza inani elifunekayo le-kojic acid dipalmitate kwizithako zesigaba seoli.
- Dibanisa isixa esicetyiswayo se-isopropyl palmitate okanye isopropyl myristate.
- Fudumeza umxube wesigaba seoli ukuya kwi-80 ° C kwaye ugcine ubushushu bemizuzu emi-5 ukuqinisekisa ukuchithwa ngokupheleleyo kwe-dipalmitate.
3. Dibanisa izigaba ze-oyile kunye namanzi:
- Yongeza kancinane isigaba seoli kwisigaba samanzi ngelixa uqhubeka uvuselela okanye u-emulsifying.
- Gcina inkqubo ye-emulsification malunga nemizuzu eli-10.
4. Lungisa i-pH yemveliso yokugqibela:
- Ukulinganisa ixabiso le-pH le-emulsion yokugqibela.
- Ukuba kukho imfuneko, lungisa i-pH ukuba iwele phakathi koluhlu olucetyiswayo lwe-5.0-8.0.
Ukulandela la manyathelo kuya kuqinisekisa ukufakwa ngokufanelekileyo kwe-kojic acid dipalmitate kwi-cosmetic formulations yakho. Umthamo ocetyiswayo wokongeza we-kojic acid dipalmitate kwizinto zokuthambisa uqhelekile malunga ne-1-5%. Nangona kunjalo, kwiimveliso ezimhlophe ngokukodwa, umlinganiselo ophakanyisiweyo ngu-3-5%.
I-Kojic acid dipalmitate ibonelela ngeenzuzo ezininzi eluswini. Ivimbela ukuveliswa kwe-melanin, ejongene ne-pigmentation yesikhumba, ekhokelela ekukhanyeni okukhanyayo nangaphezulu. Ukusetyenziswa rhoqo kweemveliso eziqulethe i-kojic acid dipalmitate kunokunceda ukunciphisa ukubonakala kwamabala, amabala, amabala, kunye nezinye iindlela ze-hyperpigmentation. Ukongezelela, esi sithako sineepropathi ze-antioxidant ezikhusela ulusu kwii-radicals zamahhala ezinobungozi, ukunciphisa iimpawu zokuguga kunye nokukhuthaza impilo yonke yolusu.
Kubalulekile ukuqaphela ukuba i-kojic acid dipalmitate kufuneka isetyenziswe ngononophelo, ngakumbi kubantu abanolusu olubuthathaka. Kuhlala kucetyiswa ukuba wenze uvavanyo lwe-patch ngaphambi kokufaka izithako ezintsha zokhathalelo lwesikhumba kwindlela yakho. Ukuba kukho naziphi na iziphumo ezingathandekiyo, yeka ukusetyenziswa ngokukhawuleza kwaye udibane nodermatologist ukuze ufumane izikhokelo ezingaphezulu.
Ukuqukumbela, i-kojic acid i-dipalmitate iyisithako esibalulekileyo kwishishini le-cosmetic, eyaziwayo ngokukhanya kwesikhumba kunye neempawu ezikhanyayo. Xa usebenzisa le khompawundi, kubalulekile ukulandela izikhokelo ezicetyiswayo ezibonelelwa ziingcali kwintsimi, njenge-Aogubio. Ngokubandakanya i-isopropyl palmitate okanye i-isopropyl myristate kwisigaba seoli kwaye ulandele amanyathelo acetyiswayo, unokunyibilikisa ngokufanelekileyo i-kojic acid dipalmitate kwaye wenze iimveliso zokhathalelo oluphezulu. Yamkela amandla e-kojic acid dipalmitate kwaye uvule amandla okuba nebala eliqaqambileyo, eliqaqambileyo.
IiNkcazo zeeMveliso
I-Kojic acid dipalmitate iguqulwe i-kojic acid derivative, engapheleli nje ekoyiseni ukungazinzi kokukhanya, ubushushu kunye ne-ion yensimbi, kodwa igcina umsebenzi we-tyrosinase inhibitory kwaye inqanda ukubunjwa kwe-melanin. I-Kojic dipalmitate inepropati ezinzileyo yekhemikhali. Ayiyi kujika ibe tyheli kwi-oxidation, i-ion yensimbi, ukukhanyisa kunye nokufudumeza.
Umsebenzi
- i-kojic acid dipalmitate luhlobo oluthile lwe-inhibitor ye-melanin. Inokuthintela umsebenzi we-tyrosinase ngokudibanisa i-ion yobhedu kwiiseli emva kokuba ingene kwiiseli zesikhumba. I-asidi ye-Kojic kunye ne-derivative yayo inempembelelo engcono yokuthintela kwi-tyrosinase kunayo nayiphi na enye i-agent emhlophe yolusu.
- i-kojic acid dipalmitate inokuphelisa i-radical yasimahla, yomeleza umsebenzi weseli kwaye igcine ukutya kusitsha.
UPHICOTHO OLUYISISEKO
| UHLALUTYO | INGCACISO | IZIPHUMO |
| Imbonakalo | Umgubo oMhlophe | Iyahambelana |
| Ivumba | Uphawu | Iyahambelana |
| Wangcamla | Uphawu | Iyahambelana |
| Isivavanyi | 99% | Iyahambelana |
| Uhlalutyo lweSieve | I-100% iphumelele i-80 mesh | Iyahambelana |
| Ilahleko ekomisweni | 5% Ubuninzi. | 1.02% |
| Uthuthu lweSulfate | 5% Ubuninzi. | 1.3% |
| Ukukhupha i-Solvent | I-Ethanol kunye naManzi | Iyahambelana |
| Intsimbi enzima | 5ppm max | Iyahambelana |
| Njengoko | 2ppm max | Iyahambelana |
| Izinyibilikisi ezishiyekileyo | 0.05% Ubukhulu. | Ibi |
| IMicrobiology | ||
| Ubalo lwePleti lulonke | 1000/g Ubuninzi | Iyahambelana |
| Igwele kunye noMngundo | 100/g Ubuninzi | Iyahambelana |
| E.Coli | Ibi | Iyahambelana |
| Salmonella | Ibi | Iyahambelana |
Usetyenziso
Iitoni zokunyamekela umzimba/ubuso, amalungiselelo okulwa nokuguga, ukukhuselwa kwelanga, emva kokutshiswa lilanga kunye nokuzitshisa, ukwenza mhlophe ulusu/ukukhanya, unyango lweentlobo ngeentlobo zeemeko zolusu lwe-hyperpigmentation okanye iziphazamiso, umz. i-solar lentigenes, i-melasma, i-chloasma, ama-scars, ama-freckles, ubudala bebala kunye neminye imimandla yesikhumba hyperpigmented
