I-Health Supplement Ursodeoxycholic Acid

I-Ursodeoxycholic acid (i-ursodiol noma i-UDCA) iyinhlanganisela eyinhloko ye-bile bear esetshenziswe kabanzi emithini yendabuko yamaShayina ngenhloso yokukhuthaza ukugeleza kwe-bile (umphumela we-choleretic). I-bile acid yesibili evela ezenzweni zebhaktheriya kukholoni, futhi ivamise ukuba khona njengengxenyana encane yengqikithi ye-bile acid esebantwini. Kodwa-ke, iguqula ukwakheka kwe-bile acid, okuholela ekwehleni kokugcwala kwama-hydrophobic kanye ne-cytotoxic bile acid. Ngaphezu kwalokho, ezinye izifundo ziye zaphakamisa ukuthi i-ursodeoxycholic acid ivikela ama-hepatocyte ngokumelene ne-bile acid-induced apoptosis. Muva nje, i-ursodeoxycholic acid isetshenziswa kakhulu ekwelapheni izifo zesibindi ze-cholestatic.