I-N-Acetylcysteine kanye Nokusebenza Kokuzivocavoca: Ukuthuthukisa Ukukhuthazela Nokubuyisela
I-N-Acetylcysteine (NAC) i-powder ithole ukunakwa okuphawulekayo emkhakheni wokuzivocavoca nokusebenza nokubuyisela. Ucwaningo oluningi luye lwabonisa ukuthi ukwesekwa kwe-NAC kungathuthukisa ukukhuthazela, kuthuthukise ukululama, futhi kungase kunciphise ingozi yokucindezeleka okwenziwe nge-oxidative okuvivinya umzimba.
Abasubathi bokubekezela bahlale befuna izindlela zokuthuthukisa ukusebenza kwabo nokubambezela ukukhathala. I-NAC, isandulela se-antioxidant glutathione, itholakale idlala indima ebalulekile ekulweni nokucindezeleka okwenziwe nge-oxidative ngesikhathi sokuzivocavoca okukhulu. Ukucindezeleka kwe-oxidative kwenzeka lapho kunokungalingani phakathi kokukhiqizwa kwama-molecule ayingozi abizwa ngokuthi ama-radicals mahhala kanye nekhono lomzimba lokubhekana nemiphumela yawo elimazayo. Le nqubo ingabangela ukukhathala kwemisipha futhi iphazamise ukululama.
Ucwaningo lubonisa ukuthi ukwesekwa kwe-NAC kungase kuthuthukise ukukhuthazela ngokunciphisa ukucindezeleka okwenziwe nge-oxidative. Ucwaningo olwanyatheliswa ku-Journal of Sports Medicine and Physical Fitness lwathola ukuthi abagibeli bamabhayisikili abathatha izithasiselo ze-NAC bathola isikhathi esithuthukisiwe sokukhathala kanye nokwanda kokutholwa komoya-mpilo uma kuqhathaniswa nalabo abathatha i-placebo. Lokhu okutholakele kusikisela ukuthi i-NAC ingasiza abasubathi ukuthi baphushe kanzima futhi benze kangcono ngesikhathi semisebenzi yokukhuthazela.
Ngaphezu kwemiphumela engaba khona ekukhuthazeleni, i-NAC iphinde yaboniswa ukuthuthukisa ukululama nokunciphisa ukulimala kwemisipha kulandela ukuvivinya umzimba okukhulu. Ucwaningo olushicilelwe ku-International Journal of Sport Nutrition and Exercise Metabolism lwathola ukuthi ukwesekwa kwe-NAC kunciphisa kakhulu izimpawu zokulimala kwemisipha nokuvuvukala ngemva kokuzivocavoca umzimba. Lokhu kuphakamisa ukuthi i-NAC ingasiza ekululameni ngokushesha futhi inciphise ubuhlungu obungemva kokuzivocavoca, okuvumela abasubathi ukuthi baphinde baqale ukuqeqeshwa ngokushesha okukhulu.
Ngaphezu kwalokho, i-NAC ibonise isithembiso ekwehliseni ingcindezi ye-oxidative ebangelwa ukuzivocavoca. Ocwaningweni olushicilelwe ku-Journal of the International Society of Sports Nutrition, abacwaningi bahlole imiphumela ye-NAC supplementation kumaka wokucindezeleka okwenziwe nge-oxidative kubadlali be-basketball. Ucwaningo luthole ukuthi ukwesekwa kwe-NAC kwehlisa izimpawu zokucindezelwa kwe-oxidative nokuthuthukisa umthamo we-antioxidant, okungenzeka kunciphise ingozi yokulimala kwemisipha kanye nokuthuthukisa ukusebenza okuphelele.
Kubalulekile ukuqaphela ukuthi nakuba i-NAC ibonisa isithembiso njengesithasiselo sokuthuthukisa ukukhuthazela nokululama, izimpendulo ngazinye zingahluka. Kuhlale kunconywa ukuthi uthintane nochwepheshe bezokunakekelwa kwempilo ngaphambi kokuqala noma yiluphi uhlobo lwemithi yokwengeza.
Ekuphetheni, i-N-Acetylcysteine powder iye yathinteka ekuthuthukiseni ukusebenza kokuzivocavoca nokubuyisela. Amandla ayo okuthuthukisa ukukhuthazela, ukunciphisa ukulimala kwemisipha, kanye nokulwa nokucindezeleka kwe-oxidative okubangelwa ukuzivocavoca kwenza kube isengezo esikhangayo kubasubathi. Nakuba ucwaningo olwengeziwe ludingeka ukuze kuqondwe ngokugcwele izindlela zalo nemiphumela, i-NAC ibonisa isithembiso njengokwengezwa okubalulekile ohlelweni lokuqeqesha lomsubathi.
Incazelo Yomkhiqizo
I-N-acetyl cysteine (NAC) ivela ku-amino acid L-cysteine. Ama-amino acid ayizingqimba zokwakha amaprotheni. I-NAC inokusetshenziswa okuningi futhi iwumuthi ogunyazwe yi-FDA.
I-N-acetyl cysteine i-antioxidant engase ibambe iqhaza ekuvimbeleni umdlavuza. Njengomuthi, usetshenziswa abahlinzeki bezempilo ukwelapha ubuthi be-acetaminophen (Tylenol). Isebenza ngokubopha izinhlobo ezinobuthi ze-acetaminophen ezakheka esibindini.
Abantu bavame ukusebenzisa i-N-acetyl cysteine ukukhwehlela nezinye izimo zamaphaphu. Ibuye isetshenziselwe umkhuhlane, iso elomile, nezinye izimo eziningi, kodwa abukho ubufakazi obuhle besayensi obusekela okuningi kwalokhu kusetshenziswa. Abukho futhi ubufakazi obuhle bokusekela ukusebenzisa i-N-acetyl cysteine ye-COVID-19.
I-N-Acetyl-L-Cysteine iyi-amino acid, ingashintshwa isuka emzimbeni we-methionine, i-cystine ingaguqulwa nomunye nomunye. I-N-Acetyl-l-cysteine ingasetshenziswa njenge-ejenti ye-mucilagenic. Ifanele ukuvinjelwa kokuphefumula okubangelwa inani elikhulu lokuvinjelwa kwe-phlegm. Ngaphezu kwalokho, ingasetshenziswa futhi ukuqeda ubuthi obunobuthi be-acetaminophen.
Umsebenzi
I-N-Acetyl-L-Cysteine iyi-amino acid, ingashintshwa isuka emzimbeni we-methionine, i-cystine ingaguqulwa nomunye nomunye. I-N-Acetyl-l-cysteine ingasetshenziswa njenge-ejenti ye-mucilagenic. Ifanele ukuvinjelwa kokuphefumula okubangelwa inani elikhulu lokuvinjelwa kwe-phlegm. Ngaphezu kwalokho, ingasetshenziswa futhi ukuqeda ubuthi obunobuthi be-acetaminophen.
