40% mmiri soluble azelaic acid

Dabere na ọkọlọtọ nhazi ọkwa ọgwụ nke FDA, azelaic acid bụ ọgwụ klaasị B, nke enwere ike iji ya n'enweghị nsogbu n'oge ime na lactation.Ọ nwere ike igbochi mmepụta na omume nke ụdị oxygen na-emeghachi omume, nke bara uru maka mgbochi mkpali na ọgwụgwọ dị iche iche. mmetụta nke ọgwụ ọjọọ. Site n'ibelata njikọ nke keratin filamentous, ọ nwere ike belata oke keratinization nke ntutu isi ma nwee ezigbo permeability na akpụkpọ ahụ.
Ọ nwere ike ịkwalite nnabata nke ngwaahịa ahụ na akpụkpọ ahụ site n'ịgbakwunye azelaic acid na ihe ịchọ mma ude. Tụkwasị na nke ahụ, azelaic acid nwere ike igbochi nje bacteria ma na-edozi ihe nzuzo nke sebum nkịtị, ma ndakọrịta ya dị oke oke n'ihi ntụpọ abụọ nke okike nke mmiri na-adịghị mma na ebe mgbaze dị elu. Ọkwa nke androgen testosterone n'ime ahụ dị oke elu, ọ na-agafe. Afọ 5 na gland sebaceous - α Ọrụ nke reductase na-agbanwe ghọọ dihydrotestosterone, nke na-eduga na hyperfunction nke sebaceous gland, na-akpata oke mmanụ secretion. Azelaic acid nwere ike ịsọ mpi 5- α Ọrụ reductase na-egbochi ntụgharị nke androgen gabigara ókè na dihydrotestosterone, na n'ikpeazụ na-egbochi oke nzuzo nke fatty acids n'efu na gland sebaceous.
Ọ nwere ike igbochi mmepụta oxygen free radicals na-arụ ọrụ mgbochi mkpali. A gbochiri hydroxylation nke ogige aromatic nke otu oxygen na-emeghachi omume na peroxidation nke arachidonic acid na vitro.
40% mmiri soluble azelaic acid mepụtara nke Shandong Binzhou Zhiyuan Biotechnology Co., Ltd. nwere nnukwu ọdịnaya ma tinye ya obere na ngwaahịa nlekọta anụ ahụ. N'ebe okpomọkụ dị n'ime ụlọ, a na-etinye ya na mmiri iji kpalie na igbari, na ngwọta mmiri na-apụta ìhè ma doo anya.
Oke keratosis nke sebaceous ducts na ntutu isi ga-egbochi follicles ntutu, ebe azelaic acid nwere mmetụta mgbochi keratotic na akpụkpọ ahụ nkịtị na acne na-arịa akpụkpọ ahụ, nke nwere ike belata njikọ nke keratin filamentous ma gbochie keratosis nke ntutu isi.