Ukunikezwa Kwefekthri Ikhwalithi Ephezulu ye-DL-Phenylalanine ne-L-Phenylalanine
Incazelo Yomkhiqizo
I-Phenylalanine iyi-amino acid enamakha ebalulekile kubantu (ehlinzekwa ukudla), i-Phenylalanine idlala indima ebalulekile ku-biosynthesis yamanye ama-amino acid futhi ibalulekile ekwakhekeni nasekusebenzeni kwamaprotheni nama-enzyme amaningi. I-Phenylalanine iguqulwa ibe yi-tyrosine, esetshenziswa ku-biosynthesis ye-dopamine ne-norepinephrine neurotransmitters. I-L-form ye-Phenylalanine ifakwe kumaprotheni, kuyilapho i-D-form isebenza njengesidambisi sezinhlungu. Ukumuncwa kwemisebe ye-ultraviolet ngePhenylalanine kusetshenziselwa ukulinganisa amanani amaprotheni.
I-L-phenylalanine iyi-L-enantiomer ye-phenylalanine. Inendima njenge-nutraceutical, i-micronutrient, i-Escherichia coli metabolite, i-Saccharomyces cerevisiae metabolite, isitshalo se-metabolite, i-algal metabolite, i-metabolite yegundane, i-xenobiotic metabolite yomuntu kanye ne-EC 3.1.3.1 inhibiphatase ye-alkali (alkali). Kuyi-erythrose 4-phosphate/phosphoenolpyruvate family amino acid, i-proteinogenic amino acid, i-phenylalanine kanye ne-L-alpha-amino acid. Isisekelo se-conjugate se-L-phenylalaninium. Kuyi-conjugate acid ye-L-phenylalaninate. I-enantiomer ye-D-phenylalanine. Kuyi-tautomer ye-L-phenylalanine zwitterion.
UKUHLAZIYWA OKUSISEKELO
| Ukuhlaziya | Incazelo | Indlela Yokuhlola |
| I-Assay (isisekelo esomile) | 99.0-101.0% | I-HPLC |
| Ukulahlekelwa ekomisweni | Hhayi Ngaphezu kuka-0.20% | Isomisi |
| Izinsalela ekushiseni | Hhayi Ngaphezu kuka-0.10% | I-Ph. Eur. |
| Izinto ezihlobene | Hhayi Ngaphezu kuka-0.5% | I-Ph. Eur. |
| I-Endotoxin* | Ngaphansi kuka-6.0 EU/g | I-Ph. Eur. |
| Isimo sesixazululo(Transmittance) | Hhayi Ngaphansi Ko-98.0% | I-Ph. Eur. |
| PH | 6.5~7.5 | I-Ph. Eur. |
| Ukuzungezisa okuqondile[α]20D | -33.5°-35.0° | I-Ph. Eur. |
| Ukuzungezisa okuqondile[α]25D | -32.7–34.7° | I-Ph. Eur. |
| I-Ammonium (NH4) | Hhayi Ngaphezu kuka-0.020% | I-Ph. Eur. |
| I-Chloride (Cl) | Hhayi Ngaphezu kuka-0.020% | I-Ph. Eur. |
| I-Sulfate (SO4) | Hhayi Ngaphezu kuka-0.020% | I-Ph. Eur. |
| Insimbi (Fe) | Hhayi Ngaphezu kuka-10 ppm | I-ICP-MS/AOAC 993.14 |
| I-Arsenic (As) |
| I-ICP-MS/AOAC 993.14 |
| I-Cadmium (Cd) |
| I-ICP-MS/AOAC 993.14 |
| Izinsimbi ezisindayo (Pb) | Hhayi Ngaphezu kuka-10 ppm | I-ICP-MS/AOAC 993.14 |
| I-Mercury (Hg) |
| I-ICP-MS/AOAC 993.14 |
Ukuhlaziywa kweMicrobial
| Inani Lepuleti Eliphelele | I-AOAC 990.12 | |
| Isamba seYeast & Mold | I-AOAC 997.02 | |
| E. Coli | I-AOAC 991.14 | |
| Ama-Coliforms | I-AOAC 991.14 | |
| I-Salmonella | Okubi | I-ELFA-AOAC |
| I-Staphylococcus | I-AOAC 2003.07 |
Umsebenzi
I-amino acid ebalulekile L-phenylalanine (Phe) iyadingeka ukuze kuhlanganiswe amaprotheni, ama-catecholamine, ne-melanin; futhi iyisandulela esibalulekile se-amino acid L-tyrosine (Tyr).
