I-Salicylic Acid - Izakhiwo
Lo mkhiqizo uyikristalu yenaliti emhlophe noma i-white crystalline powder; engenaphunga noma cishe engenaphunga; Isixazululo se-aqueous sibonisa ukusabela kwe-acidic. Lo mkhiqizo uncibilika kalula ku-ethanol noma ku-ether, uncibilika emanzini abilayo, uncibilika kancane ku-trifluoromethane, uncibilika kancane emanzini.
Isingeniso seSalicylic Acid
I-salicylic acid, eyaziwa nangokuthi i-salicylic acid, iyimpushana eyikristalu emhlophe, engenaphunga, enokunambitheka okubabayo kancane bese kuba ukunambitheka okubabayo. Itholakala ku-willow bark, amaqabunga eparele elimhlophe kanye ne-birch emnandi emvelweni. Ifomula yekhemikhali C6H4(OH)(COOH), indawo encibilikayo engu-157-159℃, kancane kancane ishintsha umbala ngaphansi kokukhanya. Ukuminyana kwesihlobo ngu-1.44. Indawo abilayo icishe ibe ngu-211°C/2.67kPa. I-Sublimation ku-76°C. Ngaphansi kwengcindezi evamile, ingabola ibe yi-phenol ne-carbon dioxide ngokushisa okusheshayo. Incibilika ku-ethanol, ether, chloroform, benzene, acetone, turpentine, ayincibiliki kalula emanzini. I-1g ye-salicylic acid ingancibilika ku-460ml wamanzi, 15ml wamanzi abilayo, 2.7ml we-ethanol, 3ml we-acetone, 3ml we-ether, 42ml we-chloroform, 135ml webenzene, 52ml we-turpentine ye-60ml ne-petroleum ye-8ml, cishe i-8ml ye-turpentine ether. Ukwengeza i-sodium phosphate, i-borax, njll. kungakhuphula ukuncibilika kwe-salicylic acid emanzini. I-pH yesisombululo se-aqueous salicylic acid ingu-2.4. I-salicylic acid ne-ferric chloride aqueous solution ikhiqiza umbala okhethekile onsomi.
Kungenzeka ukuthi awukaze uzwe nge-salicylic acid, kodwa kufanele ujwayelene ne-aspirin. Eqinisweni, i-aspirin iphuma ku-salicylic acid.Ngaphezu kwe-synthetic salicylic acid kwezinye izidakamizwa, i-salicylic acid yemvelo nayo inothile ekudleni okuningi, njengezithelo eziningi, imifino, ikhofi, itiye, amantongomane, izinongo noju. Lawa ma-salicylic acid emvelo ayisitshalo A izindlela zokuzivikela ezinambuzaneni, isikhunta nezifo.Nokho, i-salicylic acid, kungakhathaliseki ukuthi yemvelo noma yokwenziwa, ingabangela ukusabela okubi kwabanye abantu.Ukungabekezelelani kwe-salicylate kuvame ukuhlotshaniswa nemithi oyithathayo, kusukela imithi njenge-aspirin iqukethe amanani aphezulu ama-salicylates uma kuqhathaniswa nokudla. Isibonelo, ukudla okudlayo kwe-salicylic acid kuvamise ukuba ngu-10-200 mg ngosuku, uma kuqhathaniswa no-325-650 mg womthamo we-aspirin.Ucwaningo luthole ukuthi i-aspirin yandisa ingozi yesifo sesisu.
I-Salicylic Acid - Uma iqhathaniswa ne-AHA ye-Cosmetic Effects
I-salicylic acid (BHA) ikhishwa egxolweni le-willow namaqabunga e-holly, eyaziwa nangokuthi i-acid yemifino; i-asidi yesithelo (AHA) ikhishwa kumoba; iyi-asidi ekhishwe ezintweni ezimbili ezihlukene zokusetshenziswa. Zombili zingakwazi ukulawula uwoyela, ukukhipha, ukucwenga izinduna, ukushwabana kwezimbotshana, futhi kuphele amabala. Ikhasi le-asidi yesithelo elinokugxila okungaphezu kuka-50% lingasetshenziswa kuphela udokotela wesikhumba, kuyilapho ikhasi le-salicylic acid lihlukaniswa njengokwelashwa kwezokwelapha kungakhathaliseki ukuthi kugxiliwe kangakanani. Kuyaphawuleka ukuthi abantu abambalwa abafanelekile ukusebenzisa noma yikuphi ukugxila kwamanzi. I-salicylic acid, ngakho-ke ama-salon obuhle ajwayelekile awakwazi ukuyisebenzisa. Kuvunyelwe ngokomthetho ukwenza ukucwecwa kwesikhumba ngokuxutshwa kwe-asidi yesithelo engaphansi kuka-40% kumasaluni wobuhle. Uma kuqhathaniswa, i-asidi yesithelo iphephe kakhulu kune-salicylic acid. Ngokuqondene nomphumela, i-salicylic acid ivaliwe kuphela ku-stratum corneum engaphezulu, idlala indima yokwelashwa okulula nokuvimbela, futhi ukuguqulwa kokuthungwa kwesikhumba kungokwesikhashana, kuyilapho i-asidi yesithelo ingena ku-dermis ukuze iguqule ngokuyisisekelo ukuthungwa kwesikhumba, engelapheka. Yebo, ngokuqondene nemigodi ye-acne eyakhiwe yi-dermis eyonakele, umphumela we-salicylic acid awunamandla, ngakho-ke i-salicylic acid ayikwazi ukubizwa ngokuthi "i-salicylic acid peeling", ingabizwa kuphela ngokuthi "ukwelashwa kwe-salicylic acid". Ukuphepha kanye nomphumela wokucwecwa kwe-salicylic acid nokucwecwa kwe-asidi yesithelo kuhlukile, ngoba i-asidi yesithelo ayinabo ubuthi futhi ingasetshenziswa ukusuka phansi kuye phezulu (8% -15% -20% -30% -40%), ijwayela kancane kancane ngeke kubangele ukushiswa kwesikhumba, ukonakala noma imiphi imiphumela emibi. Futhi i-salicylic acid inobuthi, ukugxila okuphezulu kakhulu akufanelekile ukusetshenziswa ebusweni, kunomkhawulo othile wokuhlushwa, i-salicylic acid ene-concentration ye-3% -6% ingasetshenziswa ekukhipheni, ephakeme kuno-6% Ebola esikhumbeni. , ukuhlushwa okuphezulu kwe-salicylic acid okungama-40% kunezici eziqinile zokubola kwe-keratin.
Yini eyenza i-salicylic acid?
Ngokwemithethonqubo ye-State Food and Drug Administration (CFDA), umkhawulo ophezulu wokugxilwa kwezimonyo ngu-2%. Kufakazelwe ukuthi i-0.5% -2% salicylic acid iphephile uma kuqhathaniswa nokwelashwa kwezinduna. Akunconywa ukuthi ufune imikhiqizo enokugxila okuphezulu. Lokhu kugxila kwanele ukuthi kusebenze.
I-salicylic acid ingancibilikisa usimende phakathi kwama-cuticles futhi yenze ama-cuticles awe, ngakho-ke ingasusa ama-cuticles aminyene futhi ikhuthaze umzimba.
I-Skin metabolism: Umsebenzi oyinhloko we-stratum corneum yesikhumba ukuvikela amangqamuzana ongqimba ngalunye lwesikhumba. I-metabolism yengqimba yamaseli e-epidermal ngongqimba izophumela ngaphandle ngokwemvelo. Imvuthuluka yemvelo. I-keratin endala engawi ngokujwayelekile izokwenza isikhumba sibonakale simahhadlahhadla futhi sibuthuntu, ibambezele izinga lokugayeka kokudla esikhumbeni, futhi yakhe induna ukuze ivimbe izimbotshana.
Umphumela we-exfoliation: I-Salicylic acid ingasusa i-cuticle ngokweqile, futhi ngesikhathi esifanayo ikhuthaze ukuvuselelwa okusheshayo kwamangqamuzana e-epidermal; uma amangqamuzana e-epidermal emasha namaseli amancane agcwele ubungqabavu, ngokwemvelo azobuyisela isikhumba esibushelelezi nesithambile.
I-Shrink pores: I-Salicylic acid i-fat-soluble, futhi ingangena kungqimba olujulile lwezimbotshana ezihambisana nezindlala ze-sebaceous ezikhiqiza uwoyela, okuzuzisa ukuhlakaza ama-cuticles amadala aqoqiwe ezimbotsheni futhi kuthuthukise isimo sezimbotshana ezivinjiwe, ukuze ikwazi ukuvimba. ukwakheka kwezinduna bese shwabanisa Izimbotshana ezinwetshiwe.
Ukuvimbela izinduna: I-salicylic acid isebenza kumaseli odongeni lwezinwele, ezingasiza ekususeni izimpande zezinwele ezivinjiwe futhi kulungiswe ukuchitheka kwamaseli okungavamile. Kungavimbela ukuvaleka kwezimbotshana zezinduna ezincane futhi kusebenza kakhulu kuma-blackheads. Kunganciphisa udonga lwezinwele Ukukhishwa kwesikhumba okungavamile, kuvimbela izilonda ezintsha, kodwa akunawo umthelela ekwehliseni ukukhishwa kwe-sebum nokuqeda i-acne bacilli.
Umsebenzi we-salicylic acid ukuhlanza i-cutin eguga, okwenza isikhumba sibukeke sibucayi, futhi singabangeli induna.
Othintana naye:Yoyo Liu
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Isikhathi sokuthumela: Mar-08-2023
