Arbutin imapezeka pochita glucose ndi hydroquinone yotengedwa m'masamba a bilberry, masamba a kiranberi, masamba a mapeyala, zipatso za zimbalangondo, ndi ma blueberries, omwe amakhala kumapiri. Maselo a arbutin ndi a hydroquinone omwe amamangiriridwa ku glucose. Arbutin imalepheretsa ntchito ya tyrosinase, yomwe imakhudzidwa ndi kaphatikizidwe ka melanin pakhungu, imachepetsa kuchuluka kwa melanin, imachepetsa mtundu wa pigmentation, imathandizira kutulutsa khungu, ndikuletsa mawanga ndi mawanga. Arbutin imagawidwa mumtundu wa α ndi mtundu wa β kutengera momwe shuga ndi hydroquinone zimalumikizirana.
β-Arbutinamapangidwa ndi kaphatikizidwe mankhwala. β-Arbutin ili ndi kukhazikika kwapang'onopang'ono kuposa α-arbutin ndipo imasweka mosavuta ndi kuwala kwa UV ndi kutentha. Chifukwa cha izi, tikulimbikitsidwa kugwiritsa ntchito zinthu zosamalira khungu ndi β-arbutin usiku wokha, ndipo zikagwiritsidwa ntchito masana, tikulimbikitsidwa kuti tigwiritse ntchito limodzi ndi zoteteza ku dzuwa. Imakhalanso ndi vuto lowonongeka mosavuta ndi ma enzymes opangidwa ndi intracellular chifukwa cha kukhazikika kwapakatikati poyerekeza ndi α-arbutin. Ndi α-arbutin yomwe imalipiritsa cholakwika ichi.
- Nambala ya CAS: 497-76-7
- Nambala ya EC: 207-850-3
- Mapangidwe a maselo: C12H16O7
α-Arbutinzitha kupangidwa kudzera mu kaphatikizidwe ka enzymatic (kuwotchera kwa tizilombo). Mosiyana ndi β-arbutin, imagonjetsedwa ndi kuwala ndi kutentha, kotero imatha kugwiritsidwa ntchito usana ndi usiku ndipo imagwira ntchito mokhazikika mkati mwa selo, ndikupangitsa kuti ikhale yogwira mtima komanso yopanda poizoni. Pobwezera zofooka za β-arbutin, imakhala yokhazikika komanso yosasweka mosavuta. α-Arbutin imakhala yamphamvu nthawi 10 kuposa β-arbutin poletsa melanogenesis. α-Arbutin imalepheretsa tyrosinase kutulutsa khungu komanso kuchepetsa mawanga okalamba, ziphuphu zakumaso, zofiira pambuyo pa zilema, ndi zina zambiri. Ilinso ndi antiseptic ndi anti-inflammatory properties.
- Nambala ya CAS: 84380-01-8
- Nambala ya EC: 617-561-8
- EINECS/ELINCS: 440-470-8
- Mapangidwe a maselo: C12H16O7
Kodi Zofanana Ziti Pakati pa Arbutin ndi Alpha Arbutin?
- Arbutin ndi alpha arbutin ndi glycosylated hydroquinones.
- Alpha Arbutin ndi imodzi mwa mitundu iwiri ya arbutin.
- Zonsezi zimachokera ku magwero achilengedwe.
- Amaletsa ntchito ya tyrosinase.
- Choncho, iwo ziletsa mapangidwe melanin.
- Mitundu yonse iwiriyi imachepetsa kusinthika kwa khungu chifukwa cha kuwala kwa dzuwa kochokera kudzuwa.
- Komanso, arbutin ndi alpha arbutin amagwira ntchito ngati zowunikira khungu.
Kodi Kusiyanitsa Pakati pa Arbutin ndi Alpha Arbutin Ndi Chiyani?
Arbutin ndi glycosylated hydroquinone yomwe imalepheretsa tyrosinase, kuteteza mapangidwe a melanin, pamene alpha-arbutin ndi imodzi mwa mitundu iwiri ya arbutin yomwe imagonjetsedwa ndi kutentha, imasonyeza kukhazikika kwa kuwala komanso kusungunuka kwamadzi kwambiri kuposa mawonekedwe ena. Chifukwa chake, uku ndiye kusiyana kwakukulu pakati pa arbutin ndi alpha arbutin. Njira yotetezeka yogwiritsira ntchito arbutin malinga ndi mawonekedwe a alpha ndi 2%, ndipo mawonekedwe a beta ndi 7%.
Infographic ili m'munsiyi ikuwonetsa kusiyana pakati pa arbutin ndi alpha arbutin mu mawonekedwe a tabular kuyerekeza mbali ndi mbali.
Kodi arbutin amagwira ntchito bwanji pakhungu lanu?
Monga tikudziwira, khungu la melanocyte likangolimbikitsidwa ndi kuwala kwa kunja kwa ultraviolet, lidzatulutsa tyrosinase, yomwe imagwirizanitsa ndi tyrosine m'thupi kupanga dopamine, ndipo pamapeto pake imapanga melanin kudzera mu REDOX, kuwonongeka ndi decarboxylation reactions. Melanin, pigment udindo khungu khungu, ndiye amasamutsidwa kwa woyambira wosanjikiza, dermis, epidermis ndi zina khungu dongosolo wosanjikiza, ndiyeno ndi dander kukhetsa kapena magazi dongosolo kutulutsidwa. Komabe, pamene melanin kwambiri, izo sizingakhoze zimapukusidwa ndi thupi adzakhala precipitate mu epidermal wosanjikiza kupanga banga. Zosakaniza zina monga hydroquinone (hydroquinone), arbutin, phenylethylresorcinol, ndi azelaic acid zimatha kuletsa kumangidwa kwa tyrosinase ku tyrosine ndikuletsa melanin.
Arbutin imamanga bwino ndi enzyme tyrosinase yomwe imayambitsa kaphatikizidwe ka melanin. Ndi njira ina yamphamvu kuposa hydroquinone (yoletsedwa ku Europe ndi Australia) koma yofatsa pakhungu. Mosiyana ndi hydroquinone, yomwe ndi chinthu champhamvu chowunikira pakhungu chomwe chingakhale chankhanza kwambiri pakhungu, arbutin ndi njira yotetezeka komanso yachilengedwe. Mwachidule, beta arbutin imagwira ntchito poletsa mpikisano wa tyrosine. Izi zimalepheretsa kupanga melanin, kupangitsa khungu lanu kuwoneka lopepuka komanso lowala - komanso kuchepa kwa pigmentation, mawanga azaka, madontho a dzuwa ndi zipsera.
Nthawi yotumiza: Jul-11-2023
