Arbutin e fumanoa ka ho sebetsana le tsoekere e nang le hydroquinone e ntšitsoeng makhasi a bilberry, makhasi a cranberry, makhasi a pere, monokotšoai oa bere le li-blueberries, tse tsoang libakeng tse lithaba. Sebopeho sa limolek'hule tsa arbutin ke sa hydroquinone e kopantsoeng le tsoekere. Arbutin e thibela ts'ebetso ea tyrosinase, e amehang ts'ebetsong ea tlhahiso ea melanin letlalong, e hatella ho bokellana ho feteletseng ha melanin, e fokotsa mebala, e thusa ho lekanya letlalo le ho thibela matheba le matheba. Arbutin e arotsoe ka mofuta oa α le mofuta oa β ho latela hore na tsoekere le hydroquinone li hokahane joang.
β-Arbutine hlahisoa ke motsoako oa lik'hemik'hale. β-Arbutin e na le botsitso bo tlase ba sebopeho ho feta α-arbutin mme e robeha habonolo ke mahlaseli a UV le mocheso. Ka lebaka la tšobotsi ena, ho kgothaletswa ho sebelisa lihlahisoa tsa skincare tse nang le β-arbutin bosiu feela, 'me ha li sebelisoa motšehare, ho kgothaletswa ho sebelisoa hammoho le sunscreen. E boetse e na le bothata ba ho senyeha habonolo ke li-enzyme tsa intracellular ka lebaka la botsitso bo tlaase ba intracellular ha bo bapisoa le α-arbutin. Ke α-arbutin e lefellang bofokoli bona.
- Nomoro ea CAS: 497-76-7
- EC Nomoro: 207-850-3
- Foromo ea molek'hule: C12H16O7
α-Arbutine ka hlahiswa feela ka enzymatic synthesis (microbial fermentation). Ho fapana le β-arbutin, e hanyetsana le khanya le mocheso, kahoo e ka sebelisoa bosiu le motšehare 'me e sebetsa ka mokhoa o tsitsitseng ka har'a sele, e etsa hore e sebetse haholoanyane hape e se chefo. Ka ho lefella mefokolo ea β-arbutin, e tsitsitse haholoanyane ka sebopeho mme ha e robehe habonolo. α-Arbutin e na le matla ka makhetlo a 10 ho feta β-arbutin ho thibela melanogenesis. α-Arbutin e thibela tyrosinase ho lekanya letlalo le ho fokotsa matheba a botsofali, maqeba a makhopho, bofubelu ka mor'a likoli, le tse ling. E boetse e na le likokoana-hloko le li-anti-inflammatory properties.
- Nomoro ea CAS: 84380-01-8
- EC No. : 617-561-8
- EINECS/ELINCS: 440-470-8
- Foromo ea molek'hule: C12H16O7
Ke Litšoana Life Pakeng tsa Arbutin le Alpha Arbutin?
- Arbutin le alpha arbutin ke glycosylated hydroquinones.
- Alpha Arbutin ke e 'ngoe ea mefuta e' meli ea arbutin.
- Ka bobeli li tsoa mehloling ea tlhaho.
- Li thibela ts'ebetso ea tyrosinase.
- Kahoo, li thibela ho thehoa ha melanin.
- Mefuta ena ka bobeli e fokotsa mebala ea letlalo ka mahlaseli a kotsi a tsoang letsatsing.
- Ho feta moo, arbutin le alpha arbutin li sebetsa joalo ka lisebelisoa tse khantšang letlalo.
Phapang ke efe lipakeng tsa Arbutin le Alpha Arbutin?
Arbutin ke glycosylated hydroquinone e thibelang tyrosinase, e thibelang ho thehoa ha melanin, athe alpha-arbutin ke e 'ngoe ea mefuta e' meli ea arbutin e hanyetsanang le mocheso, e bonts'a botsitso ba leseli le thepa e phahameng ea ho qhibiliha ha metsi ho feta mofuta o mong. Kahoo, ena ke phapang ea bohlokoa lipakeng tsa arbutin le alpha arbutin. Khokahano e bolokehileng bakeng sa ts'ebeliso ea arbutin ho latela mofuta oa alpha ke 2%, 'me mofuta oa beta ke 7%.
Infographic e ka tlase e hlahisa phapang lipakeng tsa arbutin le alpha arbutin ka mokhoa oa tabular bakeng sa papiso ea lehlakore.
Arbutin e sebetsa joang letlalong la hao?
Joalokaha re tseba, hang ha melanocyte ea letlalo e hlohlelletsoa ke khanya ea ultraviolet e ka ntle, e tla hlahisa tyrosinase, e kopanyang le tyrosine 'meleng ho etsa dopamine,' me qetellong e theha melanin ka REDOX, decomposition le decarboxylation reactions. Melanin, pigment e ikarabellang bakeng sa 'mala oa letlalo, e ntan'o isoa lera la basal, dermis, epidermis le lera le leng la sebopeho sa letlalo, ebe ka mor'a ho tšolloa ha dander kapa tsamaiso ea mali e lokolloa. Leha ho le joalo, ha ho na le melanin e ngata haholo, e ke ke ea metabolized ke 'mele o tla precipitate ka epidermal lera ho etsa letheba. Lithako tse ling tse kang hydroquinone (hydroquinone), arbutin, phenylethylresorcinol, le azelaic acid li ka thibela ka nepo ho tlama ha tyrosinase ho tyrosine le ho thibela melanin.
Arbutin e tlama ka katleho le enzyme ea tyrosinase e hlahisang motsoako oa melanin. Ke mofuta o mong o matla ho feta hydroquinone (e thibetsoeng Europe le Australia) empa e boreleli letlalong. Ho fapana le hydroquinone, e leng motsoako o matla oa ho khantša letlalo o ka bang mabifi haholo letlalong, arbutin ke khetho e sireletsehileng le ea tlhaho. Ka bokhutšoanyane, beta arbutin e sebetsa ka ho thibela tyrosine ka tlholisano. Sena se thibela tlhahiso ea melanin, 'me se etsa hore letlalo la hao le bonahale le le bobebe hape le khanya - hammoho le hyperpigmentation e ntseng e fela, matheba a lilemo, matheba a letsatsi le maqeba a makhopho.
Nako ea poso: Jul-11-2023
