Benfotiamine yog ib qho kev noj haus ntxiv uas hloov hauv lub cev mus rau thiamine (vitamin B1). Thiamine pab koj lub cev hloov cov khoom noj rau hauv lub zog thiab yog qhov tseem ceeb rau lub hlwb ua haujlwm. Qee cov neeg siv benfotiamine los nce qib thiamine vim nws suav tias yog bioavailable heev.Qhov no txhais tau hais tias nws ncav cuag cov hlab ntsha sai thiab tsim cov thiamine ntau hauv lub cev.
Vim tias nws muaj cov tshuaj tiv thaiv kab mob antioxidant thiab tiv thaiv kab mob, benfotiamine kuj tseem yuav pab tau rau cov ntshav qab zib neuropathy (ntshav mob) thiab Alzheimer's kab mob.
Cov txiaj ntsig kev noj qab haus huv ntawm benfotiamine
1. Mob ntshav qab zib neuropathy
Benfotiamine therapy zoo nkaus li yog ib lub tswv yim zoo rau kev tiv thaiv kab mob ntshav qab zib nephropathy, muaj teeb meem loj ntawm ntshav qab zib, cuam tshuam nrog kev pheej hmoo siab ntawm kab mob plawv thiab kev tuag. Cov piam thaj ntau ntau ua rau muaj kev sib txuam ntawm triosephosphates; Qhov no ua rau biochemical tsis ua haujlwm thiab qhov kawg ntawm kev txhim kho ntshav qab zib nephropathy.
Cov kev tshawb fawb preclinical hauv nas tau pom tias benfotiamine tiv thaiv kev sib sau ntawm triosephosphates hauv ntshav qab zib thiab yog li inhibit qhov kev loj hlob ntawm nephropathy.
2. Kev paub txog kev txhim kho hauv Alzheimer's disease
Cov kev tshawb fawb ua ntej tau pom tias benfotiamine muab cov txiaj ntsig zoo ntawm kev paub tsis meej hauv Alzheimer's kab mob. Benfotiamine tau pom tias txo qis amyloid deposition hauv tsiaj qauv ntawm Alzheimer's kab mob. Txawm li cas los xij, cov teebmeem no tsis tau muaj pov thawj hauv tib neeg. Ib theem II kev sim tshuaj ntsuam xyuas tam sim no tab tom ntsuas seb benfotiamine tuaj yeem tiv thaiv kev poob qis hauv cov neeg mob uas muaj kev paub tsis meej me ntsis.
3. kov yeej kev haus cawv
Kev haus cawv ntev ntev yog cuam tshuam nrog kev tsis txaus ntawm cov as-ham tseem ceeb thiab cov vitamins. Alcoholism-related thiamine deficiency yog tus cwj pwm los ntawm cov kab mob neurological vim qhov poob ntawm qhov nruab nrab thiab qhov nruab nrab ntawm cov khoom dawb. Txawm hais tias kev hloov thiamine yog ib qho tseem ceeb rau cov neeg mob uas muaj cawv-vim lub hauv nruab nrab lub paj hlwb puas, benfotiamine tsis tau muaj pov thawj zoo hauv kev hla mus rau hauv nruab nrab paj hlwb los ntawm periphery.
4. Benfotiamine rau kev haus luam yeeb
Kev haus luam yeeb ua rau endothelial dysfunction, ib qho tshwm sim thaum ntxov ntawm cov kab mob plawv. Qhov no yog exacerbated los ntawm oxidative kev nyuaj siab thiab o. Hauv kev tshawb fawb ua ntej ntawm nas, benfotiamine tau pom los tiv thaiv nicotine-induced vascular dysfunction. Ib qho kev sim ua rau cov neeg tuaj yeem noj qab haus huv tau ua pov thawj tias kev kho mob luv luv nrog benfotiamine tuaj yeem rov ua haujlwm ntawm macrovascular hauv cov neeg haus luam yeeb noj qab haus huv.
5. Kev tiv thaiv raum
Cov ntaub ntawv los ntawm cov kev tshawb fawb hauv nas qhia tias benfotiamine muab kev tiv thaiv kev tiv thaiv rau cov kab mob peritoneal thiab cov raum uas nyob hauv peritoneal dialysis thiab uremia. Raws li kev tshawb fawb luam tawm nyob rau hauv Phau Ntawv Xov Xwm ntawm American Society of Nephrology, qhov sib ntxiv ntawm benfotiamine rau hauv kev noj haus ua rau muaj zog transketolase kev ua haujlwm thiab txo qis kev qhia ntawm qib siab glycation kawg cov khoom thiab lawv cov receptor.
Kev tshawb fawb los ntawm Ustuner et al. luam tawm nyob rau hauv cov ntaub so ntswg thiab Cell pom tias benfotiamine ntxiv yuav pab tau nyob rau hauv attenuating tshuaj tua kab mob nephrotoxicity ntawm amelioration ntawm oxidative kev nyuaj siab thiab o ntawm lub raum tubular hlwb.
6. Antitumor peev xwm
Cov kev tshawb fawb hauv vitro qhia tias benfotiamine tuaj yeem tiv thaiv kab mob leukemia los ntawm cov txheej txheem hu ua paraptosis cell tuag. Paraptosis yog ib hom kev tuag ntawm tes uas cuam tshuam nrog kev tsim cytoplasmic vacuole. Kev tshawb fawb txog kab lis kev cai ntawm tes los ntawm cov kws tshawb fawb ntawm Kanazawa University hauv Nyij Pooj tau pom tias benfotiamine yog ib tus neeg muaj txiaj ntsig zoo rau cov neeg mob ntshav qab zib mob ntshav qab zib mellitus uas tsis tsim nyog rau kev siv tshuaj khomob. Lawv kuj tau pom tias benfotiamine tau pom muaj kev sib koom ua ke nrog cytarabine, tus kws khomob khomob, txhawm rau tshem tawm myeloid leukemia hlwb.
7. Antioxidant zog
Benfotiamine kuj yog ib qho muaj zog antioxidant nrog cov tshuaj tiv thaiv kab mob uas tsim los ntawm inhibition ntawm prostaglandin thiab leukotriene synthesis.
Dosage: Kuv Yuav Tau Txais Benfotiamine npaum li cas?
Nco ntsoov nrog tus kws kho mob tham ua ntej noj cov tshuaj ntxiv kom paub meej tias cov tshuaj ntxiv thiab cov koob tshuaj yog tsim nyog rau koj tus kheej xav tau.
Tsis muaj kev pom zoo los yog siv tau zoo tau tsim los rau benfotiamine raws li kev kho mob rau txhua yam mob.
Feem ntau cov kev tshawb fawb hauv cov neeg mob ntshav qab zib tau siv ntau npaum li 300 mg ob zaug ib hnub. Lwm qhov kev sim tau siv ntau npaum li 900 mg ib hnub twg yam tsis muaj teeb meem loj.
Yog tias koj xav sim cov tshuaj benfotiamine, tham nrog koj tus kws kho mob. Lawv tuaj yeem qhia koj seb nws puas muaj kev nyab xeeb rau koj thiab pab koj txiav txim siab txog qhov tsim nyog.
Post lub sij hawm: Apr-04-2023
