Benfotiamine ni iki?

1. Indwara ya diabete

Ubuvuzi bwa Benfotiamine busa nkaho ari ingamba zishoboka zo kwirinda indwara ya diabete ya diabete, ingorane zikomeye za diyabete, zifitanye isano n’indwara nyinshi z’umutima n’impfu. Ubwinshi bwa glucose butera kwirundanya kwa triosephosifate; ibi biganisha ku mikorere mibi ya biohimiki kandi amaherezo ikura rya diabete ya nepropatique.

Ubushakashatsi bwibanze ku mbeba bwerekanye ko benfotiamine irinda kwirundanya kwa triosephosifate muri diyabete bityo bikabuza iterambere rya nepropatique.

2. Kumenyekanisha neza indwara ya Alzheimer

Ubushakashatsi bwibanze bwerekanye ko benfotiamine itanga ingaruka nziza kubumuga bwo kutamenya bwindwara ya Alzheimer. Benfotiamine yerekanwe kugabanya amyloide yibitse mubyitegererezo byinyamaswa zindwara ya Alzheimer. Ariko, izo ngaruka ntizagaragaye mubantu. Ikigeragezo cya kabiri cyamavuriro kirimo gusuzuma niba benfotiamine ishobora guhagarika igabanuka ryubwenge kubarwayi bafite ubumuga buke bwubwenge.

3. Gutsinda inzoga

Kunywa inzoga zidakira bifitanye isano no kubura cyane intungamubiri na vitamine. Kubura thiamine kubura inzoga birangwa na syndromes ya neurologiya bitewe no gutakaza buhoro buhoro ibintu byera byo hagati na periferiya. Nubwo gusimbuza thiamine ari ingenzi ku barwayi bafite inzoga zangiza ziterwa na sisitemu yo hagati, benfotiamine ntabwo yagaragaye ko ifite akamaro kanini mu kwinjirira mu mitsi yo hagati iturutse hanze.

4. Benfotiamine yo kunywa itabi

Kunywa itabi biganisha ku gukora nabi kwa endoteliyale, ibintu hakiri kare mu ndwara zifata umutima. Ibi byiyongera kubibazo bya okiside no gutwika. Mu bushakashatsi bwibanze ku mbeba, benfotiamine yabonetse kugira ngo ikumire imikorere mibi y'amaraso iterwa na nikotine. Ubushakashatsi bwakozwe ku bakorerabushake bafite ubuzima bwiza bwerekanye ko kuvura igihe gito hamwe na benfotiamine bishobora kugarura igice cya macrovasculaire ku banywa itabi ryiza.

5. Kurinda impyiko

Imibare yavuye mu bushakashatsi bwakozwe ku mbeba yerekana ko benfotiamine itanga ibikorwa byo gukingira ururenda rwa peritoneal nimpyiko zisigaye muri dialyse ya peritoneal na uremia. Nk’uko ubushakashatsi bwasohotse mu kinyamakuru cy’umuryango w’abanyamerika w’ubuvuzi bwa Neprologiya bubitangaza, kongeramo benfotiamine mu mirire bituma ibikorwa bya transketolase byiyongera ndetse no kugabanuka kw’ibicuruzwa bigezweho bya glycation hamwe na reseptor.

Ubushakashatsi bwakozwe na Ustuner n'abandi. yasohotse muri Tissue na Cell yasanze inyongera ya benfotiamine ishobora gufasha muguhuza antibiyotike iterwa na nephrotoxicity ikoresheje ameliorasiyo ya okiside itera no gutwika ingirabuzimafatizo.

6. Ubushobozi bwa antitumor

Mu bushakashatsi bwa vitro bwerekana ko benfotiamine ishobora guhagarika leukemia hakoreshejwe uburyo bwitwa paraptose selile. Paraptose ni ubwoko bwurupfu rwa selile rurimo gukora cytoplasmeque vacuole. Ubushakashatsi bw’umuco w'akagari bwakozwe n'abashakashatsi bo muri kaminuza ya Kanazawa mu Buyapani bwerekanye ko benfotiamine ari umukozi utanga ikizere ku barwayi ba myeloid leukemia ikaze batemerewe kuvura imiti isanzwe. Babonye kandi ko benfotiamine yerekanye ibikorwa byo gukorana na cytarabine, imiti ya chimiotherapeutique, kugira ngo ikureho selile myeloid leukemia.

7. Imiti igabanya ubukana

Benfotiamine kandi ni antioxydants ikomeye ifite imiti igabanya ubukana ikorwa binyuze mu kubuza prostaglandine na synthesis ya leukotriene.