Kaabsoosha dhirta ee loo isticmaalo alaabtayada la habeeyey waxay ka samaysan yihiin hydroxypropylmethylcellulose (HPMC), oo sidoo kale loo yaqaan hydroxypropylmethylcellulose. Hadda, waagii hore, waxa suurtogal ahayd in lagu liis gareeyo waxyaabahan sumadda:
Waxyaabaha kale:kaabsoosha dhirta (fiberka dhirta iyo biyaha)
Laakiin markaa FDA waxay bedeshay qawaaniinta calaamadaynta si ay ugu baahan tahay koofiyadaha khudradda in lagu taxay sida hydroxypropyl methylcellulose ama hydroxypropyl methylcellulose.
Sidaa darteed, marka hore waa in la ogaadaa in hydroxypropyl methylcellulose phthalate (HPMCP) ay tahay walax ka duwan HPMC tooska ah (hydroxypropyl methylcellulose ama hydroxypropyl methylcellulose). Haa, ereygani wuxuu keenayaa adduunyo kala duwan.
Sida ku cad shaxda qeexan ee soo saaraha koofiyada khudradda:
HPMC waa badeeco dhir ah oo ah nooc la safeeyey oo cellulose ah oo laga soo saaray saxarka alwaax. Marka loo eego Lifaaqa I ee Xeerka Midowga Yurub No. 1169/2011 ee ku saabsan bixinta macluumaadka cuntada ee macaamiisha, HPMC waxaa loo kala saaraa "fiber" waxaana lagu qeexay sida polymer-ka xeryahooda biyaha kaarboon oo leh saddex ama in ka badan oo monomer ah, kaas oo aan dheefshiidin ama aan nuugin xiidmaha yar ee aadanaha.
Si kastaba ha ahaatee, hababka baaritaanka shaybaarka ee hadda jira ee fiber-ka cuntada, sida AOAC 985.29, si sax ah uma oga HPMC inay tahay fiber-cunto. Si kastaba ha ahaatee, HPMC waa polymer-ka karbohaydrayt la cuni karo, fiber cunto leh oo leh saameyn jireed oo faa'iido leh, taas oo si ballaaran loo aqbalay caddaynta sayniska, sidaas darteed si ikhtiyaari ah ayaa loo shaacin karaa.
Kuwa aan wax badan ka baran kimistariga
Cellulose waa silsilad ka kooban kaarboon, hydrogen, iyo ogsijiin, sida caadiga ah ka kooban boqolaal ilaa kun oo kaarboon, hydrogen, iyo silsilado ogsijiin wada jir ah.
Hydroxyl - macnaheedu waa in ay jiraan ogsijiin iyo hydrogen ku xiran meel ku taal silsiladda cellulose, halkii ay ka ahaan lahaayeen hydrogen.
Propyl - waxaa loola jeedaa in uu jiro silsilad dhinac ah oo ku taal meel gaar ah silsiladda, halkaas oo saddex atamka kaarboon ay ku wareegsan yihiin hydrogen.
Methyl - Waxay la mid tahay propyl, laakiin maaha saddex kaarboon, laakiin hal keliya.
Isku soo wada duub afartan shay waxaadna heli doontaa=hydroxypropyl methylcellulose
Si aan si taxadar leh u baaro macluumaadkan oo aan u hubiyo in aan la iska indho-tirin ama la qurxin, waxaan hubiyay in Dr. Joseph Mercola (dhakhtar run ah oo leh cilmi-baarayaal buuxa oo buuxa) uu qoray maqaallo ku saabsan hydroxypropyl methylcellulose. Maya Haa, waxay ku hoos qoran yihiin 'Waxyaabaha Kale: Hydroxypropylmethylcellulose'.
Markaa waxaan u maleynayaa inaan si xaqiiqo ah u dhihi karno in xariiqda hoose ay tahay in hydroxypropyl methylcellulose ay tahay fiber-cunto-cunto oo ku saleysan dhirta.
Hal qayb oo inta badan ka muuqata kaabsooshayada waa hydroxypropyl methylcellulose, taas oo sida caadiga ah loo isticmaalo in lagu sameeyo kaabsal.
Hydroxypropylmethylcellulose waxaa inta badan laga helaa cellulose dhirta, taas oo ah karbohaydrayt laga helo gidaarada unugyada dhirta. Xaruntan gaarka ah waxaa caadi ahaan loo isticmaalaa soo saarista kaabsal khudradeed.
Hydroxypropylmethylcellulose sida caadiga ah waxay u muuqataa qaab hydroxypropylmethylcellulose ama HPMC ee liiska walxaha, oo la mid ah "budada sixirka".
Asal ahaan ka soo jeeda dhirta, marka la isku daro alaabta, waxay ka dhigi kartaa badeecada dhumucdeeda, waxay hubisaa qaab-dhismeed siman, iyo xitaa samaynta saameynteeda mid sii waaraya.
Waa mid hufan oo dhegdheg leh marka qoyan, taas oo ka dhigaysa wax caadi ah warshado badan, gaar ahaan sababtoo ah waxay u jilicsan tahay jirkeena waxaana loo tixgeliyaa deegaan ahaan saaxiibtinimo.
Sidee loo soo saaraa hydroxypropyl methylcellulose?
Si aan u ilaaliyo fudaydka iyo hufnaanta, waxaan si kooban u soo bandhigi doonaa mid kasta oo ka mid ah marxaladaha soo socda:
- Soo saarista alaabta ceeriin: Maaddada ugu muhiimsan ee hydroxypropyl methylcellulose waa cellulose dhirta, oo badanaa laga helo saxarka alwaax ama suufka suufka ah.
- Daawaynta Alkali: Ku daawee cellulose xal alkaline ah oo xooggan (sida sodium hydroxide) si aad ugu beddesho cellulose alkaline.
- Methylation: Tallaabadan, cellulose alkaline waxaa lagu daaweeyaa methyl chloride si loogu soo bandhigo kooxaha methyl unugyada cellulose.
- Hydroxypropylation: Tani waa meesha hydroxypropyl laga soo bilaabo. Methylcellulose waxay la falgashaa epoxy propane, taasoo keentay isku xirka kooxaha hydroxypropyl.
- Nadiifinta: Ka dib nadiifi hydroxypropyl methylcellulose ee la helay si aad uga saarto kiimikooyinka aan la falgelin iyo wasakh kale. Tan badanaa waxaa ku jira dhaqid, shaandhayn, iyo qallajin.
- Shiidida iyo granulation: Ugu dambeyntii, hydroxypropyl methylcellulose ee la qalajiyey waxaa lagu shubaa budo wanaagsan waxaana lagu dari karaa si loo helo cabbirka walxaha loo baahan yahay ee loogu talagalay codsigeeda.
Heerka methylation iyo hydroxypropylation waa la xakameyn karaa inta lagu jiro habka wax soo saarka, taas oo saameyn doonta milanka iyo sifooyinka viscosity ee hydroxypropylmethylcellulose ee la helay.
Habkani wuxuu u oggolaanayaa soo-saareyaasha inay u habeeyaan sifooyinkooda codsiyada gaarka ah si ay u daboolaan baahiyaha badeecadaha kala duwan.
Hydroxypropyl methylcellulose runtii ma yeelan kartaa adeegsiyo badan?
Haa, waa walax aad u kala duwan oo door ku leh warshado badan, waxaana jira tusaalooyin dhowr ah. Dhab ahaantii, mid iyaga ka mid ah ayaa lagu sheegay bilowgii maqaalka.
Aynu ka hadalno warshadaha.
- Warshadaha dawooyinka.
Kiniinada sii daynta joogtada ah: Hydroxypropylmethylcellulose waxaa loo isticmaalaa qaabaynta kiniinka si loo xakameeyo heerka siidaynta maaddooyinka dawooyinka firfircoon iyo in la hubiyo sii daynta daawada daba dheeraatay.
Dhibcaha indhaha: Waxaa loo isticmaalaa sida ilmada macmalka ah ee diyaarinta indhaha si loo yareeyo calaamadaha qallalan ee indhaha.
Wakiilka dahaarka: Alaabooyinka samaynta filimku waxay awood u siinayaan in loo isticmaalo sida wakiilka daahan ee kiniiniyada iyo kaabsal, hagaajinta xasiloonida iyo muuqaalka.
- In warshadaha cuntada.
Dhuxusha iyo xasiliyaha: Hydroxypropylmethylcellulose waxaa lagu daraa cuntooyin kala duwan, sida suugada, macmacaanka, iyo alaabta la dubay, si loo gaaro joogteynta la rabo ama qaabka la rabo.
Beddelka khudradda: Waa beddelka caanka ah ee jelatin ee cuntada khudradda ama khudradda, sababtoo ah waxay bixisaa joogtayn la mid ah jel, oo kuma jiraan maaddooyinka asalka xoolaha.
Xabagta dhoobada dhoobada ah iyo malaasta: Hydroxypropylmethylcellulose waxaa loo isticmaalaa sidii wakiilka biyaha haynta si loo hubiyo qalajinta joogtada ah iyo hagaajinta habsocodka.
- In alaabta la isku qurxiyo.
Dhumucda kareemka iyo kareemka wejiga: Waxay bixisaa qaab-dhismeed siman iyo joogteynta alaabta la isku qurxiyo.
Waxa kale oo ay leedahay codsiyo kale oo gaar ah.
- Wax soo saarka khad: loo isticmaalo sidii dhumuc iyo xasiliye.
- Beeraha: Waxa loo isticmaalaa sida xidhe ee iniinaha granular.
- Warshadaha dharka: waxaa loo isticmaalaa cabbirka dhar-samaynta si kor loogu qaado dunta inta lagu jiro habka todeynta.
Su'aalaha kale ee caadiga ah
- Hydroxypropyl methylcellulose si badbaado leh ma loo isticmaali karaa?
Haa.
- Hydroxypropyl methylcellulose miyuu biyo deg degi karaa?
Haa, derivative cellulose ahaan, hydroxypropylmethylcellulose waa biodegradable, taas oo ka dhigaysa in ka badan deegaanka saaxiibtinimo marka la barbar dhigo qaar ka mid ah polymers synthetic.
- Waa maxay sababta loo isticmaalo hydroxypropyl methylcellulose dhibcaha indhaha?
Hydroxypropylmethylcellulose waxay ku ekaan kartaa sifooyinka ilmada dabiiciga ah, siinta saliidayn iyo nafis indhaha qalalan iyo qallafsan. Waxyaabaha viscous-ka ah waxay ka caawiyaan inay ku sii jirto dusha sare ee indhaha in ka badan biyaha, taasoo bixisa saameyn nasasho oo dheer.
Waqtiga boostada: Oct-30-2023
