Rutin na ndụ anyị

• Na-akwalite ahụike obi

A bịa n'ihe gbasara ahụike obi gị, nchọpụta na-adịbeghị anya na-egosi na rutin nwere ike inye aka ịnọgide na-adịwanye mma nke arịa ọbara, belata mgbaka arịa ọbara, permeability nke capillary dị ala ma gbochie nsogbu ndị na-akpata ọbara mgbali elu.

Nnyocha anụmanụ nke 2018 nke e bipụtara na Experimental and Therapeutic Medicine chọpụtara na ọ na-egbochi ọrịa obi site n'igosi otu protein kinases akpọrọ ERK1/2 na Akt. Usoro rutin kacha dị irè ejiri mee ezì nwere ọrịa obi bụ 45 milligrams kwa kilogram nke arọ ahụ. Ọchịchị Rutin na-arụ ọrụ iji belata nha anụ ahụ nwụrụ anwụ n'ime obi ezì nwere ọrịa obi, na-egbochi ntinye protein mmamịrị ma kwalite mgbasa ọbara.

Nnyocha anụmanụ ọzọ nke 2014 e bipụtara na Human & Experimental Toxicology chọpụtara na ọgwụgwọ na rutin na quercetin belatara mmetụta obi na akwara nke nri nnu dị elu na oke oke. N'ezie, ngwakọta nke bioflavonoids ndị a dị irè karịa ọgwụgwọ nifedipin, ọgwụ a na-eji agwọ ọbara mgbali elu na mgbu obi.

• Na-ebelata mgbaàmà ogbu na nkwonkwo

Ọmụmụ anụmanụ na-egosi na antioxidant a nwere ike igbochi mbufụt na-adịghị ala ala. Nke ahụ na-eme ka ọ bụrụ ọgwụgwọ okike maka ọrịa ogbu na nkwonkwo. Ndị na-eme nchọpụta na Russia chọpụtara na rutin nwere ike ibelata mmepụta nke radicals n'efu na ọrịa ogbu na nkwonkwo. Ha kwubiri na enwere ike iwere ya dị ka onye na-akwado ọgwụ bara uru.

Tụkwasị na nke ahụ, nchọpụta ụlọ nyocha nke 2017 nke e bipụtara na Pharmacology chọpụtara na rutin na-eme ka ọkpụkpụ anụ ahụ dịkwuo elu n'elu nkwonkwo, na-emeziwanye cartilage na ọkpụkpụ ọkpụkpụ, ma belata mbufụt. Nke a na-egosi na ọ nwere mmetụta nchebe megide ọrịa ogbu na nkwonkwo.

• Na-alụso Ọrịa Cancer ọgụ

Rutin nwere ike bụrụ onye na-ahụ maka ọgwụgwọ maka ịlụ ọgụ kansa ọgụ n'ihi mmetụta antioxidant ya na mgbochi mkpali. E gosikwara na ọ na-ebute apoptosis, ma ọ bụ ọnwụ mkpụrụ ndụ kansa, ma gosipụta mmetụta mgbochi tumor. A na-eji Flavonoids mee ka mkpụrụ ndụ kansa mata ọgwụ mgbochi ọrịa kansa yana ịgbagha ọgwụ mgbochi maka ndị ọrịa na-anata ọgwụgwọ ọrịa kansa.

Enwere otutu nyocha nke metụtara ụmụ mmadụ, òké na sel na-atụ aro na antioxidant a na-arụ ọrụ iji belata nha etuto ahụ, mụbaa ọnwụ mkpụrụ ndụ kansa na ịbawanye oge ndụ. Nnyocha sayensị nke na-atụle ikike ọgwụ nke rutin chọpụtara na flavonoid egosipụtawo mmetụta anticancer megide ọtụtụ ọrịa cancer dị iche iche, gụnyere leukemia, cancer colon, cancer colorectal, melanoma, ọrịa imeju na ọrịa cancer akpa ume.

Nnyocha ụlọ nyocha e bipụtara na Phytotherapy Research chọpụtara na phytochemical a na-arụ ọrụ dị ka chemosensitizer n'akụkụ ahịrị mkpụrụ ndụ kansa ara mmadụ abụọ. Rutin mụbara ọrụ anticancer nke ọgwụ ndị a na-eji alụso ọrịa ọgụ nke ukwuu ma nyere aka kwụsị n'ọganihu cell nke ọma.

Nnyocha ụlọ nyocha ọzọ e bipụtara na Scientific World Journal chọpụtara na rutin na-enyere aka ịlụso neuroblastoma ọgụ, ụdị ọrịa kansa nke a na-ahụkarị na gland adrenal nke ụmụaka. Ọ kpalitere cell apoptosis ma na-achịkwa okwu nke mkpụrụ ndụ ihe nketa metụtara apoptosis.

• Na-echebe megide Ọrịa Metabolic

Nnyocha na-egosi na rutin nwere ike ichebe anyị ka anyị ghara ịmalite ịmalite ọrịa metabolic ka anyị na-eme agadi. Nnyocha metụtara oke ndị merela agadi chọpụtara na flavonoid na-egbochi mmụba nke glucose ọbara na-ebu ọnụ, ọkwa insulin na mgbali ọbara.

Ọchịchị Rutin kwalitere ọrịa metabolic metụtara ịka nká na oke site na ibelata mbufụt, mkpokọta lipid, nrụgide oxidative na ọrịa mitochondrial, nsogbu nke kpatara ọdịda nke mitochondria nke a na-ahụ n'ihe fọrọ nke nta ka ọ bụrụ otu sel nke ahụ mmadụ.

• Na-echebe ahụike ụbụrụ

Nnyocha na-egosi na rutin nwere mmetụta nchebe megide mmerụ ahụ ụbụrụ na mmebi metụtara afọ. Ọ na-enyekwa aka kwalite ahụike ụbụrụ n'ihi ihe na-egbochi mkpali na ihe antioxidant.

Na 2018, nchọpụta e bipụtara na Oxidative Medicine na Cellular Longevity na-atụ aro na bioflavonoid a na-eje ozi dị ka ihe na-ekwe nkwa neuroprotective maka ọgwụgwọ nke ọrịa neurodegenerative, gụnyere ọrịa Alzheimer, ọrịa Parkinson na ọrịa Huntington. Ndị nchọpụta kwenyere na ọ na-echebe ahụike ụbụrụ site na ibelata cytokines pro-inflammatory, melite ọrụ enzyme antioxidant na iweghachi ọrụ nke mitochondrial complex enzymes n'ime sel anyị.

• Na-egbochi mkpụkọ ọbara

Ndị na-eme nchọpụta na Harvard-Mgbakwunyere Beth Israel Deaconess Medical Center chọpụtara na rutin nwere ike bụrụ atụmatụ ọhụrụ maka igbochi thrombosis na ụdị anụmanụ. Thrombosis bụ mgbe mkpụkọ ọbara na-etolite na akwara ma ọ bụ vein. Ọkpụkpụ akwara dị omimi dị ize ndụ karịsịa n'ihi na ọ nwere ike ịkpata nsogbu ndị na-eyi ndụ egwu, dị ka ọrịa strok na nkụchi obi.

Ndị nchọpụta chọpụtara na rutin na-egbochi protein disulfide isomerase (PDI), nke a na-ezo ngwa ngwa site na platelet anyị na mkpụrụ ndụ endothelial n'oge thrombosis. Site na igbochi nzuzo nke PDI, antioxidant gosipụtara igbochi thrombosis na ụmụ oke.

Ọ bụghị naanị na ọ na-egbochi PDI, ma ọ na-egbochikwa ogige ahụ ịbanye na sel. Ndị nchọpụta chọpụtara na o nyere aka gbochie mkpụkọ ọbara n'ime akwara òké na veins, ma ekwuru na ọ bụ naanị ihe na-egbochi mkpụkọ abụọ ahụ.

• Na-eme ka mgbasa ozi dịkwuo mma

Na ọgwụ ọdịnala, a maara rutin maka ikike ya ime ka arịa ọbara sie ike ma melite mgbasa. A na-eji ya iji belata ọdịdị nke veins varicose, belata hemorrhoid yana gbochie ọrịa strok nke hemorrhagic nke veins ma ọ bụ akwara agbajiri na-akpata.

Ntụleghachi nke e bipụtara na International Journal of Molecular Sciences na-egosi na a kọrọ na nkwadebe rutin na-ebelata nke ukwuu n'ọzịza ụkwụ, na-ebelata ihe mgbu ụkwụ, ma belata nkwụsị ụkwụ, ịdị arọ na itching. Nke a nwere ike ịbụ n'ihi ikike ya ibelata mbufụt ma melite mgbasa ọbara.

njikọ: Fisetin: Senolytic Antioxidant maka ịka nká & ndị ọzọ